New alternative therapy for orofacial localized scleroderma.
Summary of "New alternative therapy for orofacial localized scleroderma."
No Summary Available
Affiliation
Clinical Associate Professor, Department of Oral Medicine and Traditional Chinese Medicine, Peking University, School and Hospital of Stomatology, Beijing and Hong Kong, China.
Journal Details
This article was published in the following journal.
Name: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
ISSN: 1528-395X
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20634110
- DOI: http://dx.doi.org/10.1016/j.tripleo.2010.04.004
Medical and Biotech [MESH] Definitions
Scleroderma, Localized
A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.
Scleroderma, Limited
The least progressive form of SYSTEMIC SCLERODERMA with skin thickening restricted to the face, neck and areas distal to the elbows and/or knees, sparing the trunk. The CREST SYNDROME is a form of limited scleroderma.
Granulomatosis, Orofacial
A condition characterized by persistent or recurrent labial enlargement, ORAL ULCER, and other orofacial manifestations in the absence of identifiable CROHN DISEASE; or SARCOIDOSIS. There is no consensus on whether orofacial granulomatosis is a distinct clinical disorder or an initial presentation of Crohn disease.
Scleroderma, Diffuse
A rapid onset form of SYSTEMIC SCLERODERMA with progressive widespread SKIN thickening over the arms, the legs and the trunk, resulting in stiffness and disability.
Scleroderma, Systemic
A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
PubMed Articles
Linear localized scleroderma is a variant of localized scleroderma characterized by linear bands and sclerotic plaques of the skin, which can result in contractures, muscle atrophy and debilitating de...
Localized Severe Scleroderma: A Retrospective Study of 26 Pediatric Patients.
Juvenile localized scleroderma includes different conditions characterized by skin hardening with increased collagen deposition. Although juvenile localized scleroderma is considered a relatively beni...
Localized scleroderma (morphea) in childhood.
Localized scleroderma or morphea is a sclerosing connective tissue disease of the skin, which may affect underlying tissues such as subcutis, muscle and bone. Many patients show extracutaneous symptom...
Localized Scleroderma Variants: Pharmacologic Implications.
Abstract Scleroderma, a complex syndrome, is a disease with varied, yet presumably related subtypes. We searched articles relating to localized scleroderma. By detailing these similarities and differe...
Clinical Trials
Efficacy and Safety of Imatinib in Scleroderma
In vitro studies have shown that imatinib 1mM inhibits strongly the growth of cutaneous fibroblasts. The hypothesis is that imatinib inhibits PDGFR which is known to be a potential target...
Scleroderma is an autoimmune disease of unknown origin. Recently, the role of environmental factors, and particularly toxic drug exposure, in the genesis of scleroderma has been suggested....
Orofacial Difficulties in Rooming-in
The purpose of this study is to identify the orofacial difficulties during the maternal breastfeeding in rooming-in.
Scleroderma is likely caused by a combination of factors, including an external trigger (infection or other exposure) and a genetic predisposition. The Scleroderma Registry will conduct ge...
Systemic sclerosis (scleroderma) is an autoimmune connective tissue disease that involves the skin and other internal organs for which there are few effective treatment options. We hypoth...
