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Randomized clinical trial of co-amoxiclav versus no antibiotic prophylaxis in varicose vein surgery (Br J Surg 2010; 97: 29-36).

13:46 EDT 19th May 2013 | BioPortfolio

Summary of "Randomized clinical trial of co-amoxiclav versus no antibiotic prophylaxis in varicose vein surgery (Br J Surg 2010; 97: 29-36)."

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Affiliation

Vascular Unit, University Hospital of Wales, Cardiff, UK.

Journal Details

This article was published in the following journal.

Name: The British journal of surgery
ISSN: 1365-2168
Pages: 1148

Links

Medical and Biotech [MESH] Definitions

Controlled Clinical Trial

Work consisting of a clinical trial involving one or more test treatments, at least one control treatment, specified outcome measures for evaluating the studied intervention, and a bias-free method for assigning patients to the test treatment. The treatment may be drugs, devices, or procedures studied for diagnostic, therapeutic, or prophylactic effectiveness. Control measures include placebos, active medicine, no-treatment, dosage forms and regimens, historical comparisons, etc. When randomization using mathematical techniques, such as the use of a random numbers table, is employed to assign patients to test or control treatments, the trial is characterized as a RANDOMIZED CONTROLLED TRIAL.

Randomized Controlled Trial

Work consisting of a clinical trial that involves at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.

Compassionate Use Trials

Providing an investigational therapy to a patient who is not eligible to receive that therapy in a clinical trial, but who has a serious or life-threatening illness for which other treatments are not available. Compassionate use trials allow patients to receive promising but not yet fully studied or approved therapies when no other treatment option exists. Also called expanded access trial.

Antibiotic Prophylaxis

Use of antibiotics before, during, or after a diagnostic, therapeutic, or surgical procedure to prevent infectious complications.

Clinical Trial

Work that is the report of a pre-planned clinical study of the safety, efficacy, or optimum dosage schedule of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques in humans selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. While most clinical trials concern humans, this publication type may be used for clinical veterinary articles meeting the requisites for humans. Specific headings for specific types and phases of clinical trials are also available.

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Author's reply: Randomized clinical trial of co-amoxiclav versus no antibiotic prophylaxis in varicose vein surgery (Br J Surg 2010; 97: 29-36).

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