Management of metabolic acidosis: does correction with sodium bicarbonate do more harm than good?

19:49 EDT 2nd September 2014 | BioPortfolio

Summary of "Management of metabolic acidosis: does correction with sodium bicarbonate do more harm than good?"

Metabolic acidosis is a very common finding in critically ill patients and is associated with increased morbidity and mortality. Metabolic acidosis in critical care patients is commonly the result of either anaerobic metabolism or failure of excretion of endogenous acid. Other causes include renal or gastrointestinal loss of bicarbonate and the intake of exogenous acids.

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Journal Details

This article was published in the following journal.

Name: British journal of hospital medicine (London, England : 2005)
ISSN: 1750-8460
Pages: 417-Unknown

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Proteins that cotransport sodium ions and bicarbonate ions across cellular membranes.

A congenital or acquired condition of insufficient production of ALDOSTERONE by the ADRENAL CORTEX leading to diminished aldosterone-mediated synthesis of Na(+)-K(+)-EXCHANGING ATPASE in renal tubular cells. Clinical symptoms include HYPERKALEMIA, sodium-wasting, HYPOTENSION, and sometimes metabolic ACIDOSIS.

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