Daptomycin as successful treatment for a refractory case of prosthetic valve endocarditis because of methicillin-sensitive Staphylococcus aureus.
Summary of "Daptomycin as successful treatment for a refractory case of prosthetic valve endocarditis because of methicillin-sensitive Staphylococcus aureus."
We report on an intravenous drug user who presented with methicillin-sensitive Staphylococcus aureus bacteremia and endocarditis of a prosthetic tricuspid valve, with a 4-cm vegetation refractory to standard antibiotic treatment. The patient responded to intravenous daptomycin therapy clinically and microbiologically, despite an absence of surgical intervention.
Division of Cardiology, United Christian Hospital, Kwun Tong, Hong Kong.
This article was published in the following journal.
Name: Heart & lung : the journal of critical care
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20800283
- DOI: http://dx.doi.org/10.1016/j.hrtlng.2010.06.002
Medical and Biotech [MESH] Definitions
Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
Mitral Valve Annuloplasty
A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annulus of the MITRAL VALVE. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs.
Dental Marginal Adaptation
The degree of approximation or fit of filling material or dental prosthetic to the tooth surface. A close marginal adaptation and seal at the interface is important for successful dental restorations.
Cardiac Valve Annuloplasty
A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annuli of HEART VALVES. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs.
Tricuspid Valve Prolapse
Abnormal protrusion of one or more of the leaflets of TRICUSPID VALVE into the RIGHT ATRIUM during SYSTOLE. This allows the backflow of blood into right atrium leading to TRICUSPID VALVE INSUFFICIENCY; SYSTOLIC MURMURS. Its most common cause is not primary valve abnormality but rather the dilation of the RIGHT VENTRICLE and the tricuspid annulus.
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