End-Stage Liver Disease: Challenges and Practice Implications.
Summary of "End-Stage Liver Disease: Challenges and Practice Implications."
As the seventh leading cause of death among people aged 25 to 64 years, end-stage liver disease (ESLD) affects many Americans in the most productive years of their lives. Despite the increasing number of individuals who are dying of ESLD, little is documented about their end of life challenges as the disease progresses. The purpose of this article is to highlight specific challenges for people with ESLD, their families, and their implications for health care providers: ascites, spontaneous bacterial peritonitis, hepatic encephalopathy, malnutrition, altered drug metabolism, renal insufficiency and hyponatremia, hepatocellular carcinoma, and pain. The authors also present a case study to illustrate disease progression and difficulties facing patients, family members, and providers.
Affiliation
School of Nursing, Oregon Health & Science University, SN 6S, 3455 South West US Veterans Hospital Road, Portland, OR 97239, USA.
Journal Details
This article was published in the following journal.
Name: The Nursing clinics of North America
ISSN: 1558-1357
Pages: 411-426
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20804886
- DOI: http://dx.doi.org/10.1016/j.cnur.2010.03.005
Medical and Biotech [MESH] Definitions
End Stage Liver Disease
Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed.
Disease Management
A broad approach to appropriate coordination of the entire disease treatment process that often involves shifting away from more expensive inpatient and acute care to areas such as preventive medicine, patient counseling and education, and outpatient care. This concept includes implications of appropriate versus inappropriate therapy on the overall cost and clinical outcome of a particular disease. (From Hosp Pharm 1995 Jul;30(7):596)
Disease Progression
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Pachytene Stage
The stage in the first meiotic prophase, following ZYGOTENE STAGE, when CROSSING OVER between homologous CHROMOSOMES begins.
Adaptation, Physiological
The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.
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