Predicting factors of unexpected peritoneal seeding in locally advanced gastric cancer: Indications for staging laparoscopy.
Summary of "Predicting factors of unexpected peritoneal seeding in locally advanced gastric cancer: Indications for staging laparoscopy."
The aim of this study is to investigate predictive factors for unexpected peritoneal seeding from clinically resectable advanced gastric cancers to suggest the indications for staging laparoscopy (SL).
A total of consecutive 589 gastric cancer patients who were clinically diagnosed with advanced gastric cancer with no metastatic disease underwent operations at Seoul St. Mary's Hospital.
A total of 72 patients (including 35 patients with seeding to distant peritoneum) were surgically diagnosed with peritoneal seeding. Borrmann type 3 (
4.475) or type 4 (
8.243) cancer, tumor invasion of T3 (
2.794) or T4 (
6.841) and tumor size (4 cm = tumor size < 8 cm;
3.723 and 8 cm = tumor size;
6.971) were predictive factors for overall peritoneal seeding. Borrmann type 3 (
3.524) or 4 (
4.695) cancer, tumor invasion of T3 (
4.378) or T4 (
15.817), and tumors involving the anterior wall (
2.762) also turned out to be predictive factors for distant peritoneal seeding.
If SL were performed by these predictive factors, this should have been performed in 42.4% of advanced gastric cancers and the detection rates for overall peritoneal seeding would have been 24.0%. J. Surg. Oncol. (c) 2010 Wiley-Liss, Inc.
Department of Surgery, Ajou University, School of Medicine, Suwon, Korea.
This article was published in the following journal.
Name: Journal of surgical oncology
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Medical and Biotech [MESH] Definitions
Portable peritoneal dialysis using the continuous (24 hours a day, 7 days a week) presence of peritoneal dialysis solution in the peritoneal cavity except for periods of drainage and instillation of fresh solution.
Disorder characterized by a wide range of structural changes in PERITONEUM, resulting from fibrogenic or inflammatory processes. Peritoneal fibrosis is a common complication in patients receiving PERITONEAL DIALYSIS and contributes to its gradual decrease in efficiency.
Natural openings in the subdiaphragmatic lymphatic plexus in the PERITONEUM, delimited by adjacent mesothelial cells. Peritoneal stomata constitute the principal pathways for the drainage of intraperitoneal contents from the PERITONEAL CAVITY to the LYMPHATIC SYSTEM.
Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.
Washing out of the peritoneal cavity. The procedure is a diagnostic as well as a therapeutic technique following abdominal trauma or inflammation.