Gastric neuroendocrine tumors in a woman with systemic lupus erythematosus.

03:06 EDT 6th July 2015 | BioPortfolio

Summary of "Gastric neuroendocrine tumors in a woman with systemic lupus erythematosus."

HISTORY AND CLINICAL
FINDINGS:
A 56-year-old woman presented with pronounced petechia. She complained about recurrent fever and night sweat for two weeks, having felt unwell during the past years.
INVESTIGATIONS:
Laboratory examinations showed thrombocytopenia, leukopenia and considerably elevated liver enzymes. Antinuclear antibodies and antibodies against double-stranded DNA were positive. Sonography showed a slightly enlarged liver with multiple surrounding lymph nodes, splenomegaly and chronic-atrophic thyroiditis. Gastroscopy revealed several polypes which were immunohistochemically classified as neuroendocrine tumors (NET). DIAGNOSIS, TREATMENT AND
COURSE:
Systemic lupus erythematosus (SLE) with involvement of several organs was diagnosed and high doses of steroids were given. The steroid was then gradually reduced and changed to azathioprine. The NET were removed endoscopically.
CONCLUSION:
Neuroendocrine tumors are rare and localised to the stomach in only 2 - 4 %. Only three cases of gastric NET in the context of SLE with autoimmune gastritis have been reported so far in the literature.

Affiliation

Medizinische Klinik I, Klinikum am Steinenberg, Kreiskliniken Reutlingen gGmbH.

Journal Details

This article was published in the following journal.

Name: Deutsche medizinische Wochenschrift (1946)
ISSN: 1439-4413
Pages: 1723-1726

Links

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Autoantibodies directed against phospholipids. These antibodies are characteristically found in patients with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; related autoimmune diseases, some non-autoimmune diseases, and also in healthy individuals.


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