Task specific fixation behaviour in macular disease.
Summary of "Task specific fixation behaviour in macular disease."
Purpose: People with central scotomas frequently use a preferred retinal locus (PRL) in place of the damaged fovea in order to fixate a target. Here we use a novel statistical technique to determine whether the retinal locus used for fixating a point target is the same as that used for reading words. Methods: Nine subjects with established macular disease and bilateral central scotomas were recruited. The retinal area used for fixating a point target and words of text was measured using a microperimeter (MP-1, Nidek Technologies, Italy). A nonparametric spatial statistical technique was used to identify whether fixation points were the same for each of these two tasks. Results: The spatial distribution of fixation points was different for point fixation and word reading in all subjects with macular disease (p<0.01). Fixation stability was also poorer for the word reading task than the fixation task (p<0.05). For control subjects without macular disease, the distribution of fixation was the same for each task (p>0.3). Conclusions: Fixation behaviour in people with macular disease is not the same for fixating a point target and for fixating words in a reading task. It can not be assumed that measuring a patient's fixation to a discrete point target accurately simulates their fixation performance on other tasks.
Affiliation
UCL Institute of Ophthalmology, London, United Kingdom.
Journal Details
This article was published in the following journal.
Name: Investigative ophthalmology & visual science
ISSN: 1552-5783
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20811056
- DOI: http://dx.doi.org/10.1167/iovs.10-5473
Medical and Biotech [MESH] Definitions
Macular Edema
Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)
Vitreoretinal Surgery
Specialized ophthalmic technique used in the surgical repair and or treatment of disorders that include retinal tears or detachment; MACULAR HOLES; hereditary retinal disease; AIDS-related retinal infections; ocular tumors; MACULAR DEGENERATION; DIABETIC RETINOPATHY; and UVEITIS.
Geographic Atrophy
A form of MACULAR DEGENERATION also known as dry macular degeneration marked by occurrence of a well-defined progressive lesion or atrophy in the central part of the RETINA called the MACULA LUTEA. It is distinguishable from WET MACULAR DEGENERATION in that the latter involves neovascular exudates.
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Analyses for a specific enzyme activity, or of the level of a specific enzyme that is used to assess health and disease risk, for early detection of disease or disease prediction, diagnosis, and change in disease status.
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