Periprosthetic joint infection: the economic impact of methicillin-resistant infections.
Summary of "Periprosthetic joint infection: the economic impact of methicillin-resistant infections."
The orthopedic community has begun to witness a worrisome rise in the incidence of periprosthetic joint infections (PJIs) caused by resistant organisms. Besides other challenges associated with treating these infections, it appears that these infections may pose a higher cost compared to infections caused by sensitive organisms. Significantly higher cost of care for treatment of infections due to methicillin-resistant organisms were seen at a mean of $107,264 per case compared to $68,053 for treating PJI caused by sensitive strains (P < .0001). More effective strategies for preventing the spread of infections caused by resistant organisms need to be implemented to ease the social and economic strains facing the orthopedic community due to resistant organisms.
Affiliation
Rothman Institute of Orthopedics at Thomas Jefferson University, Philadelphia, PA 19107, USA.
Journal Details
This article was published in the following journal.
Name: The Journal of arthroplasty
ISSN: 1532-8406
Pages: 103-7
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20570103
- DOI: http://dx.doi.org/10.1016/j.arth.2010.04.011
Medical and Biotech [MESH] Definitions
Methicillin-resistant Staphylococcus Aureus
A strain of Staphylococcus aureus that is non-susceptible to the action of METHICILLIN. The mechanism of resistance usually involves modification of normal or the presence of acquired PENICILLIN BINDING PROTEINS.
Economics, Medical
Economic aspects of the field of medicine, the medical profession, and health care. It includes the economic and financial impact of disease in general on the patient, the physician, society, or government.
Methicillin
One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Periprosthetic Fractures
Fractures around joint replacement prosthetics or implants. They can occur intraoperatively or postoperatively.
Methicillin Resistance
Non-susceptibility of a microbe to the action of METHICILLIN, a semi-synthetic penicillin derivative.
PubMed Articles
Novel Biomarkers to Detect Infection in Revision Hip and Knee Arthroplasties.
BACKGROUND: A periprosthetic joint infection is one of the most challenging complications associated with THA and TKA. In the diagnostic process for detecting a periprosthetic joint infection, one of...
Breast implant infections: is cefazolin enough?
BACKGROUND:: Bacterial infection is a well-known risk of breast implant surgery, occurring in 2.0 to 2.5 percent of cosmetic cases and up to 20 percent of reconstructive cases. The Centers for Disease...
Diagnosis of periprosthetic joint infections of the hip and knee.
No preferred test for diagnosis of periprosthetic joint infection exists, and the algorithm for the workup of patients suspected of infection remains unclear. The work group evaluated the available li...
Objective-To compare methicillin-resistant Staphylococcus pseudintermedius (MRSP) and methicillin-susceptible S pseudintermedius (MSSP) infections in dogs. Design-Multicenter case-control study. Anima...
INTRODUCTION: It is unknown whether intraoperative subcutaneous wound closing culture samples (WCCS) are useful to predict periprosthetic joint infection (PJI). METHOD: Here we prospectively followed...
Clinical Trials
Daptomycin With Rifampin for Treatment of Staphylococcal Prosthetic Joint Infection
To determine the outcome and safety of a combined antimicrobial treatment involving daptomycin and surgical approach involving retention or short-interval two-stage exchange of the implant...
This clinical trial tests the hypothesis that body decolonization of patients with recurrent community-associated (CA) MRSA infections will significantly reduce the likelihood of recurrent...
Nosocomial infections is a major problem in intensive care units due to both growing incidence and pathogens implicated which become increasingly resistant to antibiotics. According to the...
The goal of this study is to further the investigators' understanding of community acquired methicillin-resistant Staph Aureus (CA-MRSA) and treatment of it by developing real-world sustai...
The purpose of this study is to evaluate the prevalence of pre-surgical patients who are MRSA carriers. From an evidence-based practice perspective, findings from this study can be conside...