Mode of Delivery and Outcomes in Very Low-Birth-Weight Infants in the Vertex Presentation.

23:48 EDT 3rd September 2015 | BioPortfolio

Summary of "Mode of Delivery and Outcomes in Very Low-Birth-Weight Infants in the Vertex Presentation."

We sought to determine the relationship between mode of delivery and neonatal outcomes in infants <1500 g in a vertex presentation. This was a retrospective cohort study of singleton, vertex-presenting infants weighing <1500 g in a level III neonatal intensive care unit between July 1993 and July 2006. Infants were divided into vaginal or cesarean delivery, and outcomes were compared with univariable and multivariable analysis. Of the 937 infants that met inclusion criteria, 402 (42.9%) underwent cesarean delivery. After controlling for potential confounding variables, there was no increased odds of death (odds ratio [OR] = 1.6: 95% confidence interval [CI] 0.8 to 3.0), severe intraventricular hemorrhage (IVH; OR = 1.2: 95% CI 0.7 to 1.2), necrotizing enterocolitis (OR = 0.82: 95% CI 0.35 to 1.9), or sepsis (OR = 0.79: 95% CI 0.44 to 13) in the vaginally delivered group compared with the cesarean group. In a post hoc analysis, this study had 80% power to detect an absolute difference in death or severe IVH of 6% between study groups, with an alpha of 0.05. In our population of very low-birth-weight infants, there was no association between mode of delivery and neonatal outcomes.


Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York.

Journal Details

This article was published in the following journal.

Name: American journal of perinatology
ISSN: 1098-8785


PubMed Articles [12136 Associated PubMed Articles listed on BioPortfolio]

Salivary and serum cortisol and relation to blood pressure in infancy and early childhood in very-low-birth-weight infants.

Programming of the HPA axis possibly explains the relation between IUGR and/or preterm birth and elevated blood pressure in later life. Very-low-birth-weight infants (birth weight

A large head circumference is more strongly associated with unplanned cesarean or instrumental delivery and neonatal complications than a high birth weight.

Fetal size impacts on perinatal outcomes. We queried whether the fetal head, as the fetal part interfacing with the birth canal, might impact on obstetric outcomes more than birth weight. We examined ...

Preterm Prelabor Rupture of Membranes and Outcome of Very-Low-Birth-Weight Infants in the German Neonatal Network.

It was the aim of our study to evaluate the independent effect of preterm prelabor rupture of membranes (PPROM) as a cause of preterm delivery on mortality during primary hospital stay and significant...

Long-chain polyunsaturated fatty acids supplementation in preterm infants.

Extremely low birth weight and very low birth weight infants are born immature and are commonly sick and are, therefore, not able to receive appropriate enteral or sufficient parenteral nutrition to m...

The ProPre-Save Study: Effects of Probiotics and Prebiotics Alone or Combined on Necrotizing Enterocolitis in Very Low Birth Weight Infants.

To test the efficacy of probiotic and prebiotic, alone or combined (synbiotic), on the prevention of necrotizing enterocolitis (NEC) in very low birth weight (VLBW) infants.

Clinical Trials [3797 Associated Clinical Trials listed on BioPortfolio]

Probiotics-Supplemented Feeding in Extremely Low Birth Weight Infants

The overall purpose of this research is to test whether adding a supplement to the feeding of extremely low birth weight infant (infants weighing less than 2 pound 2 oz at birth) will help...

Effects of Volume Guarantee With Pressure Supported vs. Synchronized Intermittent Mandatory Ventilation in VLBW Infants

Studies in preterm infants have shown that adding volume guarantee (VG) to synchronized modes of ventilation is not only feasible but also advantageous for providing more constant and desi...

Erythropoietin Treatment in Extremely Low Birth Weight Infants

Objective: To investigate whether recombinant EPO reduces the need for transfusion in extremely low birth weight (ELBW) infants and to determine the optimal time for treatment. The concen...

Iron Supplementation of Marginally Low Birth Weight Infants

Iron is essential for brain development and there is a well established association between iron deficiency in infants and poor neurological development. In Sweden, about 5% of newborns ha...

Effect of Tactile and Kinesthetic Stimulation on Very Low Birth Weight Preterm Infants

Two groups of preterm infants with birth weight equal to or less than 1500 grams will be studied. One group will receive the standard care and the other will receive standard care plus mat...

Medical and Biotech [MESH] Definitions

An infant having a birth weight of 2500 gm. (5.5 lb.) or less but INFANT, VERY LOW BIRTH WEIGHT is available for infants having a birth weight of 1500 grams (3.3 lb.) or less.

An infant whose weight at birth is less than 1000 grams (2.2 lbs), regardless of gestational age.

An infant whose weight at birth is less than 1500 grams (3.3 lbs), regardless of gestational age.

The position or orientation of the FETUS at near term or during OBSTETRIC LABOR, determined by its relation to the SPINE of the mother and the birth canal. The normal position is a vertical, cephalic presentation with the fetal vertex flexed on the NECK.

The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.


Relevant Topics

Latest News Clinical Trials Research Drugs Reports Corporate
Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...

Latest News Clinical Trials Research Drugs Reports Corporate
Antiretroviral Therapy Clostridium Difficile Ebola HIV & AIDS Infectious Diseases Influenza Malaria Measles Sepsis Swine Flu Tropical Medicine Tuberculosis Infectious diseases are caused by pathogenic...


Searches Linking to this Article