Does the Oxford Knee Score Complement, Concur, or Contradict the American Knee Society Score?
Summary of "Does the Oxford Knee Score Complement, Concur, or Contradict the American Knee Society Score?"
The American Knee Society Score (AKSS) and the Oxford Knee Score (OKS) are commonly used outcome assessment tools following total knee arthroplasty. The literature is sparse with regard to direct correlation between the AKSS and the OKS. The present study aimed to elucidate any direct correlation between these two scoring systems. Preoperative and 1-year postoperative AKSS and OKS from 379 patients were analyzed statistically. Regression equations were developed based on curve fit models. The study found a good correlation between the two scoring systems. The OKS can be used as a screening tool to identify which patients need to be assessed clinically in the short term (<2 years) following total knee arthroplasty (TKA). This will have significant cost-benefit implications. It is also possible to predict the AKSS from OKS using mathematical equations developed for this study. This method of predicting the AKSS from the OKS has not previously been described.
Manor Hospital, Walsall, West Midlands, UK.
This article was published in the following journal.
Name: The Journal of arthroplasty
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20817390
- DOI: http://dx.doi.org/10.1016/j.arth.2010.05.032
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Medical and Biotech [MESH] Definitions
Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A and COMPLEMENT C5B. These include the different forms of C3/C5 convertases in the classical and the alternative pathways of COMPLEMENT ACTIVATION. Both cleavages take place at the C-terminal of an ARGININE residue.
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Complement activation initiated by the binding of COMPLEMENT C1 to ANTIGEN-ANTIBODY COMPLEXES at the COMPLEMENT C1Q subunit. This leads to the sequential activation of COMPLEMENT C1R and COMPLEMENT C1S subunits. Activated C1s cleaves COMPLEMENT C4 and COMPLEMENT C2 forming the membrane-bound classical C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and the assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.
A serine protease that is the complex of COMPLEMENT C3B and COMPLEMENT FACTOR BB. It cleaves multiple COMPLEMENT C3 into COMPLEMENT C3A (anaphylatoxin) and COMPLEMENT C3B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY.