The Chemistry of Caries: Remineralization and Demineralization Events with Direct Clinical Relevance.
Summary of "The Chemistry of Caries: Remineralization and Demineralization Events with Direct Clinical Relevance."
Dental caries is a site-specific disease that undergoes many cycles of demineralization and remineralization during lesion development. Because of its developmental characteristics dynamics, the caries lesion can be arrested and even repaired at its early stages without operative intervention by increasing the net mineral gain during the demineralization and remineralization cycles. This result can be accomplished by reducing the effect of etiological factors such as cariogenic biofilms and diet, and increasing the efficacy of remineralizing agents such as saliva and fluoride.
Department of Cariology, Restorative Sciences, and Endodontics, School of Dentistry, University of Michigan, 1011 North University B305, Ann Arbor, MI 48109-1078, USA.
This article was published in the following journal.
Name: Dental clinics of North America
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20630190
- DOI: http://dx.doi.org/10.1016/j.cden.2010.03.004
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Medical and Biotech [MESH] Definitions
A tooth's loss of minerals, such as calcium in hydroxyapatite from the tooth matrix, caused by acidic exposure. An example of the occurrence of demineralization is in the formation of dental caries.
Removal of mineral constituents or salts from bone or bone tissue. Demineralization is used as a method of studying bone strength and bone chemistry.
The specialty of ANALYTIC CHEMISTRY applied to assays of physiologically important substances found in blood, urine, tissues, and other biological fluids for the purpose of aiding the physician in making a diagnosis or following therapy.
The predisposition to tooth decay (DENTAL CARIES).
Investigative techniques used in pre-clinical and clinical research, epidemiology, chemistry, immunology, genetics, etc. They do not include techniques specifically applied to DIAGNOSIS; THERAPEUTICS; anesthesia and analgesia; SURGICAL PROCEDURES, OPERATIVE; and DENTISTRY.