The Effect of Age and Gender on 59 Trace-Element Contents in Human Rib Bone Investigated by Inductively Coupled Plasma Mass Spectrometry.
Summary of "The Effect of Age and Gender on 59 Trace-Element Contents in Human Rib Bone Investigated by Inductively Coupled Plasma Mass Spectrometry."
The effect of age and gender on 59 trace-element contents in rib bone of 80 apparently healthy 15-55-year-old women (n = 38) and men (n = 42) was investigated by inductively coupled plasma mass spectrometry. Mean values (M ± SΕΜ) for the mass fraction (milligrams per kilogram, on dry-weight basis) of Ba, Bi, Cd, Ce, Cu, Dy, Er, Gd, La, Li, Mn, Mo, Nd, Pb, Pr, Rb, Sm, Sr, Tb, Tl, U, Yb, and Zn for both female and male taken together were: Ba 2.5 ± 0.2, Bi 0.015 ± 0.002, Cd 0.044 ± 0.005, Ce 0.029 ± 0.002, Cu 1.05 ± 0.06, Dy 0.0020 ± 0.0003, Er 0.0011 ± 0.0002, Gd 0.0015 ± 0.0001, La 0.020 ± 0.002, Li 0.040 ± 0.002, Mn 0.354 ± 0.004, Mo 0.052 ± 0.006, Nd 0.011 ± 0.001, Pb 2.24 ± 0.14, Pr 0.0032 ± 0.0004, Rb 1.51 ± 0.06, Sm 0.0014 ± 0.0001, Sr 291 ± 20, Tb 0.00041 ± 0.00005, Tl 0.00050 ± 0.00003, U 0.0013 ± 0.0001, Yb 0.00072 ± 0.00007, and Zn 92.8 ± 1.5, respectively. The upper limit of mean contents of Ag, Al, B, Be, Br, Cr, Cs, Hg, Ho, Lu, Ni, Sb, Te, Th, Ti, Tm, and Y were: Ag ≤ 0.011, Al ≤ 7.2, B ≤ 0.65, Be ≤ 0.0032, Br ≤ 3.9, Cr ≤ 0.25, Cs ≤ 0.0077, Hg ≤ 0.018, Ho ≤ 0.00053, Lu ≤ 0.00024, Ni ≤ 1.05, Sb ≤ 0.0096, Te ≤ 0.0057, Th ≤ 0.0030, Ti ≤ 2.8, Tm ≤ 0.00006, and Y ≤ 0.0047, respectively. In all bone samples, the contents of As, Au, Co, Eu, Ga, Hf, Ir, Nb, Pd, Pt, Re, Rh, Sc, Se, Sn, Ta, V, W, and Zr were under detection limits. The Ce, Dy, Er, Gd, La, Nd, Pr, Sm, Tb, and Yb contents increase with age. Higher Sr mass fraction is typical of female rib as compared to those in male bone.
Affiliation
Northwestern University, Chicago, IL, 60611, USA.
Journal Details
This article was published in the following journal.
Name: Biological trace element research
ISSN: 1559-0720
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20838924
- DOI: http://dx.doi.org/10.1007/s12011-010-8837-4
Medical and Biotech [MESH] Definitions
Tin
A trace element that is required in bone formation. It has the atomic symbol Sn, atomic number 50, and atomic weight 118.71.
Molybdenum
A metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.94. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase. (From Dorland, 27th ed)
Zinc
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Manganese
A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Sodium Selenite
Selenious acid, disodium salt. It is used therapeutically to supply the trace element selenium.
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