Isolated Hypersomnia Due to Bilateral Thalamic Infarcts.
Summary of "Isolated Hypersomnia Due to Bilateral Thalamic Infarcts."
We describe a unique patient who developed hypersomnia as the sole presenting symptom of bilateral thalamic infarcts.
Affiliation
Department of Neurology, University of Missouri School of Medicine, Columbia, Missouri.
Journal Details
This article was published in the following journal.
Name: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
ISSN: 1532-8511
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20851635
- DOI: http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2010.05.013
Medical and Biotech [MESH] Definitions
Mediodorsal Thalamic Nucleus
The largest of the medial nuclei of the thalamus. It makes extensive connections with most of the other thalamic nuclei.
Disorders Of Excessive Somnolence
Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
Cadasil
A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)
Thalamic Nuclei
Several groups of nuclei in the thalamus that serve as the major relay centers for sensory impulses in the brain.
Ticlopidine
Ticlopidine is an effective inhibitor of platelet aggregation. The drug has been found to significantly reduce infarction size in acute myocardial infarcts and is an effective antithrombotic agent in arteriovenous fistulas, aorto-coronary bypass grafts, ischemic heart disease, venous thrombosis, and arteriosclerosis.
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