Clinical trials in interventional pain management: Optimizing chances for success?

11:44 EDT 18th September 2014 | BioPortfolio

Summary of "Clinical trials in interventional pain management: Optimizing chances for success?"

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Affiliation

Department of Anesthesiology, Critical Care and Multidisciplinary Pain Centre, Ziekenhuis Oost-Limburg, Genk, Belgium; Department of Anesthesiology and Pain Management, Maastricht University Medical Centre, Maastricht, The Netherlands.

Journal Details

This article was published in the following journal.

Name: Pain
ISSN: 1872-6623
Pages:

Links

PubMed Articles [31258 Associated PubMed Articles listed on BioPortfolio]

Development of an interventional pain management specific instrument for methodologic quality assessment of nonrandomized studies of interventional techniques.

The major component of a systematic review is assessment of the methodologic quality and bias of randomized and nonrandomized trials. While there are multiple instruments available to assess the metho...

Interventional Spine Procedures for Management of Chronic Low Back Pain-A Primer.

Chronic low back pain is a common clinical condition. Percutaneous fluoroscopic-guided interventions are safe and effective procedures for the management of chronic low back pain, which can be perform...

Assessment of methodologic quality of randomized trials of interventional techniques: development of an interventional pain management specific instrument.

A major component of a systematic review is an assessment of the methodological quality and bias of randomized trials. The most commonly utilized methodological quality assessment and bias assessment ...

Development and implementation of PROgmatic: A clinical trial management system for pragmatic multi-centre trials, optimised for electronic data capture and patient-reported outcomes.

Many clinical trials are conducted as explanatory trials, but the applicability of results from explanatory trials to clinical practice may be questioned. Pragmatic trials elucidate both benefits and ...

Pharmacogenetics of Chronic Pain Management.

The experience of chronic pain is one of the commonest reasons individuals seek medical attention, making the management of chronic pain a major issue in clinical practice. Drug metabolism and respons...

Clinical Trials [5150 Associated Clinical Trials listed on BioPortfolio]

Improving Pain Management in Patients With Nonhematologic Cancer

RATIONALE: A pain assessment and management system for people with cancer may help doctors accurately assess and plan more effective pain treatment for patients who have cancer. PURPOSE: ...

Gabapentin for Postoperative Pain Management After Cardiac Surgery With Median Sternotomy

In this study we will focus on the postoperative recovery. A successful postoperative recovery should bring the patient to at least to the pre-surgical level. This can probably be achieved...

Pain Quantification and Pain Management in Interventional Radiology (IR)

Primary Objectives: - To measure and record patients' pain levels before, during, and after standard procedures performed in IR. - To compare different procedures to res...

Laser Acupuncture for Pain Prevention in Neonates

Pain prevention and/or therapy in neonates is still a challenge. It is widely accepted that early pain experience can have a tremendous impact on the pain memory. We want to investigate if...

Instanyl® Non-Interventional Study

The aim of this study is to describe the use of Instanyl® (Intranasal fentanyl spray) in the treatment of breakthrough pain (BTP) in cancer patients by success of dose titration and distr...

Medical and Biotech [MESH] Definitions

The application of industrial management practice to systematically maintain and improve organization-wide performance. Effectiveness and success are determined and assessed by quantitative quality measures.

Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.

Work that is the report of a pre-planned clinical study of the safety, efficacy, or optimum dosage schedule of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques in humans selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. While most clinical trials concern humans, this publication type may be used for clinical veterinary articles meeting the requisites for humans. Specific headings for specific types and phases of clinical trials are also available.

Earlier than planned termination of clinical trials.

The influence of study results on the chances of publication and the tendency of investigators, reviewers, and editors to submit or accept manuscripts for publication based on the direction or strength of the study findings. Publication bias has an impact on the interpretation of clinical trials and meta-analyses. Bias can be minimized by insistence by editors on high-quality research, thorough literature reviews, acknowledgement of conflicts of interest, modification of peer review practices, etc.

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