Mantoux test reactions among children managed for tuberculosis in Maiduguri, Nigeria.
Summary of "Mantoux test reactions among children managed for tuberculosis in Maiduguri, Nigeria."
Abstract We conducted a study of Mantoux reactions in children managed for tuberculosis (TB) at the University of Maiduguri Teaching Hospital (UMTH) over a period of 4 y. Of the 97 eligible children managed for various forms of TB on whom a Mantoux test was conducted, 82 (84.5%) had a negative Mantoux reaction and 15 (15.5%) had a positive reaction. No statistically significant difference was found in relation to age groups and sex between the patients with positive and negative Mantoux reactions (p = 0.602 and p = 0.484, respectively). No significant difference in Mantoux reaction was observed among BCG-vaccinated and non-vaccinated children (p = 0.321). Although malnutrition and HIV infection were significantly associated with a negative Mantoux reaction, disseminated TB was not associated. We therefore recommend proper clinical assessment and other investigations for the diagnosis of TB in children in settings with a high prevalence of HIV infection and malnutrition, as Mantoux reaction results may be unreliable.
Affiliation
From the Department of Paediatrics, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria.
Journal Details
This article was published in the following journal.
Name: Scandinavian journal of infectious diseases
ISSN: 1651-1980
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20849365
- DOI: http://dx.doi.org/10.3109/00365548.2010.515606
Medical and Biotech [MESH] Definitions
Latent Tuberculosis
The dormant form of TUBERCULOSIS where the person shows no obvious symptoms and no sign of the causative agent (Mycobacterium tuberculosis) in the SPUTUM despite being positive for tuberculosis infection skin test.
Tuberculin
A protein extracted from boiled culture of tubercle bacilli (MYCOBACTERIUM TUBERCULOSIS). It is used in the tuberculin skin test (TUBERCULIN TEST) for the diagnosis of tuberculosis infection in asymptomatic persons.
Stanford-binet Test
An individual intelligence test designed primarily for school children to predict school performance and the ability to adjust to everyday demands.
False Negative Reactions
Negative test results in subjects who possess the attribute for which the test is conducted. The labeling of diseased persons as healthy when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)
False Positive Reactions
Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)
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