Compositionally Graded Hydroxyapatite/Tricalcium Phosphate Coating on Ti by Laser and Induction Plasma.
Summary of "Compositionally Graded Hydroxyapatite/Tricalcium Phosphate Coating on Ti by Laser and Induction Plasma."
In this study, we report fabrication of compositionally graded HA coatings on Ti by combining Laser Engineering Net Shaping (LENSâ„¢) and radio frequency (RF) induction plasma spraying processes. Initially, HA powder was embedded into the Ti substrates using LENSâ„¢ forming a Ti-HA composite layer. Later, RF induction plasma spraying was used to deposit HA on these Ti substrates with Ti-HA composite layer on top. Phase analysis by X-ray diffraction (XRD) indicated phase transformation of HA to Î²-tricalcium phosphate (TCP) in the laser processed coating. Laser processed coatings showed the formation of a metallurgically sound and diffused substrate-coating interface, which significantly increased the coating hardness to 922Â±183 Hvfrom that of the base metal hardness of 189Â±22 Hv. In laser processed multilayer coating, the compositionally graded nature was successfully achieved, however with severe cracking and consequent decrease in the flexural strength of the coating. To obtain a structurally stable coating with composition gradient across the coating thickness, a phase pure HA layer was sprayed on top of the laser processed single layer coatings using an induction plasma spray. The plasma sprayed HA coatings were strongly adherent to the LENSâ„¢-TCP coatings with adhesive bond strength of 21 MPa. In vitro biocompatibility of these coatings, using human fetal osteoblast cells (hFOB), showed clear improvement in cellular activity from uncoated Ti to LENSâ„¢-TCP coated Ti and reached maximum in plasma sprayed HA coating.
W. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, WashingtonStateUniversity, Pullman, WA99164, USA.
This article was published in the following journal.
Name: Acta biomaterialia
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20854939
- DOI: http://dx.doi.org/10.1016/j.actbio.2010.09.016
Medical and Biotech [MESH] Definitions
Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue.
Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.
A technique utilizing a laser coupled to a catheter which is used in the dilatation of occluded blood vessels. This includes laser thermal angioplasty where the laser energy heats up a metal tip, and direct laser angioplasty where the laser energy directly ablates the occlusion. One form of the latter approach uses an EXCIMER LASER which creates microscopically precise cuts without thermal injury. When laser angioplasty is performed in combination with balloon angioplasty it is called laser-assisted balloon angioplasty (ANGIOPLASTY, BALLOON, LASER-ASSISTED).
Angioplasty, Balloon, Laser-assisted
Techniques using laser energy in combination with a balloon catheter to perform angioplasty. These procedures can take several forms including: 1, laser fiber delivering the energy while the inflated balloon centers the fiber and occludes the blood flow; 2, balloon angioplasty immediately following laser angioplasty; or 3, laser energy transmitted through angioplasty balloons that contain an internal fiber.
Laser Therapy, Low-level
Treatment using irradiation with LASER light of low power intensity so that the effects are not due to heat, as in LASER THERAPY. These non-thermal effects are thought to be mediated by a photochemical reaction that alters CELL MEMBRANE PERMEABILITY, leading to increased mRNA synthesis and CELL PROLIFERATION. Low-level laser therapy has been used for a wide variety of conditions, but most frequently for wound healing and pain control.
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