Idiopathic Orbital Inflammation Leading to Unilateral Blindness Over a 2-Day Presentation in a Child.

09:13 EDT 24th May 2015 | BioPortfolio

Summary of "Idiopathic Orbital Inflammation Leading to Unilateral Blindness Over a 2-Day Presentation in a Child."

An 8-year-old boy developed vision loss to no light perception on the left side over a 2-day period. He initially presented with unilateral eyelid swelling, which progressed to bilateral edema and an eventual left-sided orbital apex syndrome. Orbital imaging revealed enlarged extraocular muscles, and biopsy confirmed idiopathic orbital inflammation. Despite subsequent orbital decompression, high-dose steroids, and additional steroid-sparing therapy, he did not regain vision after 9 months of follow up.

Affiliation

*Scheie Eye Institute, University of Pennsylvania School of Medicine; †Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia; and ‡Department of Ophthalmology, Children's Hospital of Philadelphia, University of Pennsylva

Journal Details

This article was published in the following journal.

Name: Ophthalmic plastic and reconstructive surgery
ISSN: 1537-2677
Pages:

Links

PubMed Articles [11871 Associated PubMed Articles listed on BioPortfolio]

Idiopathic Inflammatory Orbital Myositis Presenting with Vision Loss.

Abstract We present a first case of 58-year-old man with vision loss in a biopsy-proven idiopathic inflammatory orbital tendon sparing myositis. Tests for thyroid autoantibodies were negative at the i...

An analysis of IgG4-related disease (IgG4-RD) among idiopathic orbital inflammations and benign lymphoid hyperplasias using two consensus-based diagnostic criteria for IgG4-RD.

To determine the proportion of idiopathic orbital inflammation (IOI) and orbital benign lymphoid hyperplasia (OBLH) accounted for by immunoglobulin (Ig)G4-related orbital disease (IgG4-ROD) using the ...

Re: "Local Steroid Injection for Management of Different Types of Acute Idiopathic Orbital Inflammation: An 8-Year Study"

Unusual presentation of an orbital cavernous hemangioma.

An orbital cavernous hemangioma is composed of large, ectatic, endothelium-lined, blood-filled spaces. Inflammatory cells, such as lymphocytes, are rarely found in the interstitium. In this case repor...

Prepubertal unilateral gynecomastia in the absence of endocrine abnormalities.

Gynecomastia is defined as the excessive development of breast tissue in males, which can occur as unilateral or bilateral. Although the overall prevalence of gynecomastia is 40%-65%, the prepubertal ...

Clinical Trials [2301 Associated Clinical Trials listed on BioPortfolio]

Survey of Patients With Idiopathic Orbital Inflammation Syndrome

The purpose of this study is to characterise the clinical features, histopathology and the treatment outcomes of patients with idiopathic orbital inflammation syndrome.

Unilateral Blindness/ Unilateral Deafness-Relation to Neck Pain

Neck pain is a common complaint in the general population affecting 10-15% of the general population. females more than men. Known risk factors are: Trauma, Repetitive lifting of heavy obj...

Prospective Multicenter Trial to Compare Preformed vs Non Preformed Orbital Implants

Accuracy of posttraumatic orbital reconstruction of the meidal orbital wall and/or floor is better with preoperatively preformed orbital implants than with non-preformed orbital implants.

MRI Perfusion Curves Typology and Orbital Tumors (PERFORM)

Orbital masses develop at the expense of the orbital structures lacrimal glands, oculomotor muscles, optic nerve, meningeal spaces, peripheral nerves, bone wall, orbital fat, lymphoid stru...

The Role of TSH Receptor, PPAR-r, IGF-1R, IGF and Cytokines in Different Stages of Graves’Ophthalmopathy

The exact mechanism of the pathogenesis of Graves’ ophthalmopathy is still unknown. Histopathologically, extraocular muscle inflammation and orbital fat inflammation are two prominent ch...

Medical and Biotech [MESH] Definitions

A nonspecific tumor-like inflammatory lesion in the ORBIT of the eye. It is usually composed of mature LYMPHOCYTES; PLASMA CELLS; MACROPHAGES; LEUKOCYTES with varying degrees of FIBROSIS. Orbital pseudotumors are often associated with inflammation of the extraocular muscles (ORBITAL MYOSITIS) or inflammation of the lacrimal glands (DACRYOADENITIS).

Inflammation of the extraocular muscle of the eye. It is characterized by swelling which can lead to ischemia, fibrosis, or ORBITAL PSEUDOTUMOR.

A group of interstitial lung diseases with no known etiology. There are several entities with varying patterns of inflammation and fibrosis. They are classified by their distinct clinical-radiological-pathological features and prognosis. They include IDIOPATHIC PULMONARY FIBROSIS; CRYPTOGENIC ORGANIZING PNEUMONIA; and others.

A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change.

An idiopathic syndrome characterized by the formation of granulation tissue in the anterior cavernous sinus or superior orbital fissure, producing a painful ophthalmoplegia. (Adams et al., Principles of Neurology, 6th ed, p271)

Search BioPortfolio:
Loading
Advertisement

Relevant Topic

Pediatrics
Latest News Clinical Trials Research Drugs Reports Corporate
Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...

Advertisement

Searches Linking to this Article