Advertisement
Advertise here Publish your press releases here Sponsor BioPortfolio
Follow us on Twitter Sign up for daily news and research emails Contributors wanted

Idiopathic Orbital Inflammation Leading to Unilateral Blindness Over a 2-Day Presentation in a Child.

19:05 EDT 23rd April 2014 | BioPortfolio

Summary of "Idiopathic Orbital Inflammation Leading to Unilateral Blindness Over a 2-Day Presentation in a Child."

An 8-year-old boy developed vision loss to no light perception on the left side over a 2-day period. He initially presented with unilateral eyelid swelling, which progressed to bilateral edema and an eventual left-sided orbital apex syndrome. Orbital imaging revealed enlarged extraocular muscles, and biopsy confirmed idiopathic orbital inflammation. Despite subsequent orbital decompression, high-dose steroids, and additional steroid-sparing therapy, he did not regain vision after 9 months of follow up.

Affiliation

*Scheie Eye Institute, University of Pennsylvania School of Medicine; †Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia; and ‡Department of Ophthalmology, Children's Hospital of Philadelphia, University of Pennsylva

Journal Details

This article was published in the following journal.

Name: Ophthalmic plastic and reconstructive surgery
ISSN: 1537-2677
Pages:

Links

PubMed Articles [8602 Associated PubMed Articles listed on BioPortfolio]

Idiopathic orbital inflammation associated with panuveitis in an adult and a review of the literature.

To report an unusual case of idiopathic orbital inflammation associated with panuveitis.

Complete Resolution of Idiopathic Sclerosing Orbital Inflammation after Treatment with Rituximab.

Invisibility of moving objects: a core symptom of motion blindness.

Although the higher brain mechanisms of seeing moving objects have been deeply investigated, motion blindness remains a rare and enigmatic symptom. Very few case reports well describe the detailed sym...

Idiopathic sclerosing orbital inflammation and active graves' orbitopathy.

Bilateral orbital complications of paediatric rhinosinusitis.

The spread of infection from the ethmoid sinuses to the orbit occurs directly through a congenital dehiscence of the lamina papyracea or via haematogenous spread through ophthalmic venous system. Henc...

Clinical Trials [2032 Associated Clinical Trials listed on BioPortfolio]

Survey of Patients With Idiopathic Orbital Inflammation Syndrome

The purpose of this study is to characterise the clinical features, histopathology and the treatment outcomes of patients with idiopathic orbital inflammation syndrome.

Unilateral Blindness/ Unilateral Deafness-Relation to Neck Pain

Neck pain is a common complaint in the general population affecting 10-15% of the general population. females more than men. Known risk factors are: Trauma, Repetitive lifting of heavy obj...

Prospective Multicenter Trial to Compare Preformed vs Non Preformed Orbital Implants

Accuracy of posttraumatic orbital reconstruction of the meidal orbital wall and/or floor is better with preoperatively preformed orbital implants than with non-preformed orbital implants.

The Role of TSH Receptor, PPAR-r, IGF-1R, IGF and Cytokines in Different Stages of Graves’Ophthalmopathy

The exact mechanism of the pathogenesis of Graves’ ophthalmopathy is still unknown. Histopathologically, extraocular muscle inflammation and orbital fat inflammation are two prominent ch...

Rituximab in the Treatment of Scleritis and Non-Infectious Orbital Inflammation

The purpose of this study is to assess the safety and tolerability of Rituximab in refractory scleritis and non-infectious orbital inflammation.

Medical and Biotech [MESH] Definitions

A nonspecific tumor-like inflammatory lesion in the ORBIT of the eye. It is usually composed of mature LYMPHOCYTES; PLASMA CELLS; MACROPHAGES; LEUKOCYTES with varying degrees of FIBROSIS. Orbital pseudotumors are often associated with inflammation of the extraocular muscles (ORBITAL MYOSITIS) or inflammation of the lacrimal glands (DACRYOADENITIS).

Inflammation of the extraocular muscle of the eye. It is characterized by swelling which can lead to ischemia, fibrosis, or ORBITAL PSEUDOTUMOR.

A group of interstitial lung diseases with no known etiology. There are several entities with varying patterns of inflammation and fibrosis. They are classified by their distinct clinical-radiological-pathological features and prognosis. They include IDIOPATHIC PULMONARY FIBROSIS; CRYPTOGENIC ORGANIZING PNEUMONIA; and others.

A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change.

An idiopathic syndrome characterized by the formation of granulation tissue in the anterior cavernous sinus or superior orbital fissure, producing a painful ophthalmoplegia. (Adams et al., Principles of Neurology, 6th ed, p271)

Search BioPortfolio: