Hormonal contraception and HIV acquisition: reanalysis using marginal structural modeling.

02:32 EDT 2nd April 2015 | BioPortfolio

Summary of "Hormonal contraception and HIV acquisition: reanalysis using marginal structural modeling."

Hormonal contraceptives are used widely worldwide; their effect on HIV acquisition remains unresolved. We reanalyzed data from the Hormonal Contraception and HIV Study using marginal structural modeling to reduce selection bias due to time-dependent confounding. Replicating our original analysis closely, we found that depo-medroxyprogesterone acetate (DMPA) but not combined oral contraceptive (COC) was associated with increased HIV acquisition. Also, young (18-24 years) but not older women who used DMPA and COCs were at increased HIV risk.

Affiliation

Behavioral and Biomedical Research Division, Family Health International, Research Triangle Park, North Carolina 27709, USA. cmorrison@fhi.org

Journal Details

This article was published in the following journal.

Name: AIDS (London, England)
ISSN: 1473-5571
Pages: 1778-81

Links

PubMed Articles [9641 Associated PubMed Articles listed on BioPortfolio]

Hormonal Contraception and Risk of Psychiatric and Other Noncommunicable Diseases in HIV-Infected Women.

Background: Hormonal contraception use is common among human immunodeficiency virus (HIV)-infected women. Risk of psychiatric and other noninfectious complications of hormonal contraception use has no...

Hormonal Contraception and the Risk of HIV Acquisition: An Individual Participant Data Meta-analysis.

Observational studies of a putative association between hormonal contraception (HC) and HIV acquisition have produced conflicting results. We conducted an individual participant data (IPD) meta-analys...

Repeated use of pre- and postcoital hormonal contraception for prevention of pregnancy.

Repeated use of postcoital hormonal contraception is not currently recommended due to the higher risk of side effects and lower contraceptive effectiveness compared to other modern methods of contrace...

Effect of Hormonal Contraception on the Function of Plasmacytoid Dendritic Cells and Distribution of Immune Cell Populations in the Female Reproductive Tract.

Epidemiological evidence suggests an association between the use of hormonal contraception and an increased risk of acquiring sexually transmitted diseases including HIV-1. We sought to elucidate the ...

Combined hormonal versus nonhormonal versus progestin-only contraception in lactation.

Postpartum contraception improves the health of mothers and children by lengthening birth intervals. For lactating women, contraception choices are limited by concerns about hormonal effects on milk q...

Clinical Trials [805 Associated Clinical Trials listed on BioPortfolio]

Computer-Assisted Provision of Reproductive Health Care

This project seeks to demonstrate that computer kiosks in a clinic waiting room can improve access to hormonal contraception and screening for sexually transmitted infections. The study wi...

A Randomized Trial of IUD Versus Hormonal Contraception in HIV-infected Women in Zambia

A randomized trial of the intrauterine contraceptive device (IUD) versus user's choice hormonal contraception (injectable progestins or oral contraceptive pills) among HIV-infected, recent...

Substrate Utilization and Hormonal Status in Women

Women sexual hormones (i.e. estrogen) are involved in the regulation of substrate utilization and storage. Being under oral contraception (OC) may conduct to metabolic and hormonal modific...

Impact of Different Contraceptives on the Immune System of HIV Infected Women in Zambia

In this study, 66 HIV-infected women who desire contraception will be randomly assigned to use either an IUD or Depo Provera, and will be followed for six months. The study is intended to...

Trial of Immediate Versus Delayed Initiation of Transdermal Hormonal Contraception After Therapeutic Abortion

This is a randomized, controlled trial investigating whether immediate versus standard, “Sunday Start”, initiation of transdermal hormonal contraception (the patch) in post-abortion su...

Medical and Biotech [MESH] Definitions

Methods of contraception in which physical, chemical, or biological means are used to prevent the SPERM from reaching the fertilizable OVUM.

The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS, marginal PERIODONTITIS, injury, and ASCORBIC ACID DEFICIENCY.

Behavior patterns of those practicing CONTRACEPTION.

Prevention of CONCEPTION by blocking fertility temporarily, or permanently (STERILIZATION, REPRODUCTIVE). Common means of reversible contraception include NATURAL FAMILY PLANNING METHODS; CONTRACEPTIVE AGENTS; or CONTRACEPTIVE DEVICES.

The degree of approximation or fit of filling material or dental prosthetic to the tooth surface. A close marginal adaptation and seal at the interface is important for successful dental restorations.

Search BioPortfolio:
Loading
Advertisement

Relevant Topic

The top 5 most promising drugs (February 2014)
Latest News Clinical Trials Research Drugs Reports Corporate
THE FIVE MOST PROMISING DRUGS LAUNCHED OR RECEIVING APPROVAL February 2014 Drug Disease Company Gazyva™ Chronic lymphocytic leukemia Biogen Idec/Genentech/ F. Hoffman-La Roche ...

Advertisement

Searches Linking to this Article