Design of and technical challenges involved in a framework for multicentric radiotherapy treatment planning studies.
Summary of "Design of and technical challenges involved in a framework for multicentric radiotherapy treatment planning studies."
This report introduces a framework for comparing radiotherapy treatment planning in multicentric in silico clinical trials. Quality assurance, data incompatibility, transfer and storage issues, and uniform analysis of results are discussed. The solutions that are given provide a useful guide for the set-up of future multicentric planning studies or public repositories of high quality data.
Affiliation
Department of Radiation Oncology (MAASTRO), Maastricht University Medical Centre, The Netherlands.
Journal Details
This article was published in the following journal.
Name: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
ISSN: 1879-0887
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20864198
- DOI: http://dx.doi.org/10.1016/j.radonc.2010.08.009
Medical and Biotech [MESH] Definitions
Radiotherapy, Adjuvant
Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
Denture Design
The plan, delineation, and location of actual structural elements of dentures. The design can relate to retainers, stress-breakers, occlusal rests, flanges, framework, lingual or palatal bars, reciprocal arms, etc.
Dental Prosthesis Design
The plan and delineation of dental prostheses in general or a specific dental prosthesis. It does not include DENTURE DESIGN. The framework usually consists of metal.
Radiotherapy Dosage
The total amount of radiation absorbed by tissues as a result of radiotherapy.
Adaptation, Physiological
The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.
PubMed Articles
Monte Carlo role in radiobiological modelling of radiotherapy outcomes.
Radiobiological models are essential components of modern radiotherapy. They are increasingly applied to optimize and evaluate the quality of different treatment planning modalities. They are frequent...
Castleman disease (CD) is a rare lymphoproliferative disorder. Two clinical entities are described: a unicentric form with disease confined to a single lymph node region and a multicentric form charac...
Adjuvant and Definitive Radiotherapy for Adrenocortical Carcinoma.
PURPOSE: To evaluate the impact of both adjuvant and definitive radiotherapy on local control of adrenocortical carcinoma. METHODS AND MATERIALS: Outcomes were analyzed from 58 patients with 64 instan...
Radiotherapy of brain tumors : New techniques and treatment strategies for.
Through a variety of technical enhancements modern radiotherapy offers the possibility to apply a high dose to an exactly defined target volume while the surrounding normal tissue is optimally spared....
Our case illustrates the difficulties involved in diagnosing multicentric Castleman's disease (MCD) in a human immunodeficiency virus-infected man with febrile episodes and malaise. In the absence of...
Clinical Trials
Multicentric Cohort of Melanoma Patients in Ile de France Area
This is a multicentric prospective cohort of all stage melanoma patients from AP-HP ,the largest consortium of University hospitals over Europe. 7 investigation sites (7 dermatological ser...
This trial is aimed to study the efficacy of 4 weekly cycles of rituximab in HIV-infected patients with multicentric Castleman disease (giant lymph node hyperplasia) dependent on chemother...
An Adaptive Design Trial Of GW274150 In The Treatment Of Acute Migraine
Nitric oxide (NO) is likely to be involved in the development of migraine headache. Nitric oxide synthase (NOS) is an important chemical involved in the production of NO. Reduction of NOS,...
Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial
To determine the maximum tolerated dose (MTD) of AZD6244 or AZD2171 when combined with pre-operative capecitabine and radiotherapy in patients with locally advanced rectal cancer.
Optimizing an Online Motivational Tobacco Cessation Program
The current study will test the effectiveness of five potentially important tailoring factors (decisional framework, message framing, self-efficacy, navigation autonomy, and proactive outr...
