Track topics on Twitter Track topics that are important to you
The mammalian hair follicle (HF) is a complex structure composed of several distinct cell layers. The HF is an ectodermal appendage that resides in the skin, and unlike other tissues and organs, it possesses the remarkable ability to self-renew and undergoes a hair cycle that persists in adult life. Stem cells in the bulge region of the HF, as well as dermal papilla cells, play key roles in the regulation of successive hair cycles. Recent advances in molecular genetics have enabled the identification of many genes and pathways that are involved in HF morphogenesis and cycling. Furthermore, mutations in some of these genes are associated with hereditary hair diseases in humans. Identification of causative genes for hair diseases has provided a better understanding of the crucial roles of these genes in HF morphogenesis, development, and hair growth in humans.
Department of Dermatology, Columbia University, New York, NY 10032, USA.
This article was published in the following journal.
Name: Annual review of genomics and human genetics
Woolly hair (WH) is a hair abnormality that is primarily characterised by tightly curled hair with abnormal growth.
Hereditary hair loss in human is a group of clinically and genetically heterogeneous disorders. It is characterized by sparse to complete absence of hair on the scalp and other parts of the body. In f...
Hair abnormalities in ectodermal dysplasia may be difficult to identify. Among 16 patients with ectodermal dysplasia trichoscopy (hair dermoscopy) revealed predominance of pilosebaceous units with 1 h...
Hair loss is a common cause of morbidity for many women. As a key member of the woman's health care team, the obstetrician/gynecologist may be the first person to evaluate the complaint of hair loss. ...
The Yangtze River Delta white goat is a goat breed that can produce high quality brush hair (Type III hair) around the world. This study aimed to compare Type III hair and non-Type III hair goat skin ...
The purpose of this study is to learn more about how hair removal with lasers achieves, what appears to be, permanent hair reduction. Laser hair removal has become one of the most popular...
The purpose of this research study is to better understand African American hair and scalp, its biologic appearance and how this relates to African Americans' perceptions of their hair and...
This study examines the best way to teach genetics to family medicine residents. First year family medicine residents at the University of Toronto will be taught basic clinical genetics as...
The purpose of the study is to create a Nephrology Tissue Biobank enabling the study of kidney disease from the perspectives of epidemiology, genetics and molecular biology.
We hope to learn more about the biology of psychiatric illness with the hope of improving the diagnosis and treatment of such psychiatric conditions as major depression.
Hair grooming and cleansing aids or other products meant for topical application to hair, usually human. They include sprays, bleaches, conditioners, rinses, shampoos, nutrient lotions, etc.
Auditory sensory cells of organ of Corti, usually placed in one row medially to the core of spongy bone (the modiolus). Inner hair cells are in fewer numbers than the OUTER AUDITORY HAIR CELLS, and their stereocilia are approximately twice as thick as those of the outer hair cells.
Sensory cells in the organ of Corti, characterized by their apical stereocilia (hair-like projections). The inner and outer hair cells, as defined by their proximity to the core of spongy bone (the modiolus), change morphologically along the cochlea. Towards the cochlear apex, the length of hair cell bodies and their apical stereocilia increase, allowing differential responses to various frequencies of sound.
Chemicals that are used to oxidize pigments in HAIR.
A tube-like invagination of the EPIDERMIS from which the hair shaft develops and into which SEBACEOUS GLANDS open. The hair follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (Stedman, 26th ed) Follicles of very long hairs extend into the subcutaneous layer of tissue under the SKIN.
Latest News Clinical Trials Research Drugs Reports Corporate
Acne Dermatology Eczema Psoriasis Wound Care Dermatology is the medical specialty concerned with the diagnosis and treatment of skin disorders (Oxford Medical Dictionary). As well as studying how the skin works, dermatology covers...