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21:02 EDT 24th August 2016 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 1–25 of 1,500,000+

How Can the Health System Retain Women in HIV Treatment for a Lifetime? A Discrete Choice Experiment in Ethiopia and Mozambique.

Option B+, an approach that involves provision of antiretroviral therapy (ART) to all HIV-infected pregnant women for life, is the preferred strategy for prevention of mother to child transmission of HIV. Lifelong retention in care is essential to its success. We conducted a discrete choice experiment in Ethiopia and Mozambique to identify health system characteristics preferred by HIV-infected women to promote continuity of care.

Mineralocorticoid receptor antagonists: a patent evaluation of US20150284376A1.

Recent clinical studies showed that mineralocorticoid receptor antagonists (MRAs) are able to markedly reduce the overall and cardiovascular mortality in patients with left ventricular systolic dysfunction and mild or severe symptoms of chronic heart failure (HF). Beyond cardiac diseases, new indications of MRAs increase exponentially, especially in patients with impaired renal function. Most of the developed mineralocorticoid receptor antagonists are now non-steroidal. Identifying so-called "kidney friendl...

Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma.

Both yaws and trachoma are endemic in the Pacific. Mass treatment with azithromycin is the mainstay of the WHO strategy for both the eradication of yaws and the elimination of trachoma as a public health problem, but the dose recommended for trachoma is lower than that for yaws. In countries where both diseases are endemic, there is a potential for synergy between yaws and trachoma control programs if mass treatment with the lower dose of azithromycin was shown to be effective for the treatment of yaws. In ...

In this issue.

An oral-gavage dosing method for zebrafish.

Dynamic graphs for clear reporting.

News updates.

The transgenerational impacts of hypoxia.

Illuminating melanoma at the molecular level.

Super-sniffer mice put their noses to the grindstone.


Methods in microbiome research.

Response to Protocol Review Scenario: Leave the research presentations to the principal investigators.

What are the limits of confidentiality for IACUC members?

Response to Protocol Review Scenario: Loose lips can sink ships-and potentially careers and institutions.

Response to Protocol Review Scenario: A word from USDA and OLAW.

Response to Protocol Review Scenario: A matter of interpretation.

The tuberculin skin test in monkeys.

Passive narcosis for anesthesia induction in cotton rats (Sigmodon hispidus).

Cotton rats (Sigmodon hispidus) are widely used as animal models for infectious disease and immunological research. They emulate many aspects of human disease pathogenesis, and the introduction of cotton rat-specific immunological reagents, cell lines and sequencing of relevant genes have all helped to increase the popularity of this disease model. However, the use of cotton rats is problematic owing to their propensity for aggressive responses when handled, which can lead to escape, increased stress to the...

Tools for organizing training, part 3.

The enrichment club.

September Updates: People &Places.

Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.

Harlequin Ichthyosis is a severe skin disease caused by mutations in the human gene encoding ABCA12. Here, we characterize a novel mutation in intron 29 of the mouse Abca12 gene that leads to the loss of a 5' splice donor site and truncation of the Abca12 RNA transcript. Homozygous mutants of this smooth skin or smsk allele die perinatally with shiny translucent skin, typical of animal models of Harlequin Ichthyosis. Characterization of smsk mutant skin showed that the delivery of glucosylceramides and CORN...

Vaccine adjuvants: why and how.

Novel vaccine strategies include the so-called subunit vaccines, which encompass only the part of the pathogen to which immune recognition results in protection. The high purity of these vaccines make adverse events less likely, but it also makes the vaccines less immunogenic and therefore potentially less effective. Vaccine adjuvants that increase and modulate the immunogenicity of the vaccine are therefore added to solve this problem. Besides aluminium salts, which have been used in vaccines for 90 years...

Genome sequencing identifies a non-coding variant in the MCDR1 locus as a cause of macular dystrophy.

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