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21:22 EST 25th January 2015 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 26–50 of 31,000+

1154648

Functional diversity enhances the resistance of ecosystem multifunctionality to aridity in Mediterranean drylands.

We used a functional trait-based approach to assess the impacts of aridity and shrub encroachment on the functional structure of Mediterranean dryland communities (functional diversity (FD) and community-weighted mean trait values (CWM)), and to evaluate how these functional attributes ultimately affect multifunctionality (i.e. the provision of several ecosystem functions simultaneously). Shrub encroachment (the increase in the abundance/cover of shrubs) is a major land cover change that is taking place in ...

1154635

Flemons, D., & Gralnik, L. M. (2013). Relational suicide assessment: Risks, resources, and possibilities for safety. New York, NY: W.W. Norton & Company, 254 pp. $36.00.

1154631

Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/ABCG2 transcription in human cancer cells.

We report a novel cyclic-AMP (cAMP) response element (CRE) in the human BCRP promoter that is functional in human cancer cell lines of multiple lineages. 8Br-cAMP increased the activity of a BCRP promoter reporter construct and BCRP mRNA in human carcinoma cells. Activation of the epidermal growth factor receptor (EGFR) pathway also led to an increase in BCRP promoter reporter activity and to phosphorylation of the c-AMP response element binding protein (CREB) via two major downstream EGFR signaling pathway...

1154626

Fish Intake and Risk of Liver Cancer: A Meta-Analysis.

Increasing laboratory findings indicate that n-3 fatty acids, mainly derived from fish, inhibit cancer development and progression, but results from epidemiologic studies have been inconsistent and inconclusive.

1154511

F pocket flexibility influences the tapasin dependence of two differentially disease-associated MHC Class I proteins.

The human major histocompatibility complex (MHC) class I protein HLA-B*27:05 is statistically associated with ankylosing spondylitis (AS), unlike HLA-B*27:09, which differs in a single amino acid in the F pocket of the peptide binding groove. To understand how this unique amino acid difference leads to a different behavior of the proteins in the cell, we have investigated the conformational stability of both proteins using a combination of in silico and experimental approaches. Here, we show that the bindin...

1154432

Fatty Infiltration of the Thymus in Response to Illness in the Pediatric Population.

Under physiologic stress, glucocorticoids contribute to thymic involution. While steroids enhance fatty infiltration, this change has not been well studied in the pediatric thymus during illness. Evaluation of 130 thymuses from fetuses, infants and children determined the frequency of thymic fatty infiltration to be low (25%), particularly in fetal thymus (4%). In most cases, fatty infiltration was focal. There was a significant correlation with duration of illness, but not with patient age, gestational age...

1154400

Full genome sequence analysis of a wild, non-MLV-related type 2 Hungarian PRRSV variant isolated in Europe.

Porcine reproductive and respiratory syndrome virus (PRRSV) is a widespread pathogen of pigs causing significant economic losses to the swine industry. The expanding diversity of PRRSV strains makes the diagnosis, control and eradication of the disease more and more difficult. In the present study, the authors report the full genome sequencing of a Type 2 PRRSV strain isolated from piglet carcasses in Hungary. Next generation sequencing was used to determine the complete genome sequence of the isolate (PRRS...

Thursday 29th December 1154

Feasibility of Omitting Cortical Renorrhaphy During Robotic Partial Nephrectomy: A Matched Analysis.

Objective: To assess the safety of omitting cortical renorrhaphy during robotic partial nephrectomy and measure preliminary functional outcomes. Patients and Methods: Fifteen robotic partial nephrectomies were performed with a running, base-layer suture for the collecting system and vessel hemostasis but without cortical renorrhaphy. The non-renorrhaphy group was matched 1:2 by RENAL nephrometry score to a running, sliding-clip cortical renorrhaphy group retrospectively. Intraoperative blood loss, urine lea...

Thursday 1st December 1154

Feasibility of sulfide control in sewers by reuse of iron rich drinking water treatment sludge.

Dosage of iron salt is the most commonly used method for sulfide control in sewer networks but incurs high chemical costs. In this study, we experimentally investigate the feasibility of using iron rich drinking water treatment sludge for sulfide control in sewers. A lab-scale rising main sewer biofilm reactor was used. The sulfide concentration in the effluent decreased from 15.5 to 19.8 mgS/L (without dosing) to below 0.7-2.3 mgS/L at a sludge dosing rate achieving an iron to total dissolved inorganic s...

Tuesday 25th October 1154

Features and predictors of activity limitations and participation restriction 2 years after intensive rehabilitation following first-ever stroke.

Although stroke-related disability has been extensively studied, only few studies have investigated Participation restriction in chronic stroke survivors.

Monday 3rd October 1154

Fornical and non-fornical projections from the rat hippocampal formation to the anterior thalamic nuclei.

The hippocampal formation and anterior thalamic nuclei form part of an interconnected network thought to support memory. A central pathway in this mnemonic network comprises the direct projections from the hippocampal formation to the anterior thalamic nuclei, projections that, in the primate brain, originate in the subicular cortices to reach the anterior thalamic nuclei by way of the fornix. In the rat brain, additional pathways involving the internal capsule have been described, linking the dorsal subicu...

Monday 5th September 1154

Fast Neutron Radiotherapy in the Treatment of Malignant Pleural Mesothelioma.

Malignant pleural mesothelioma (MPM) is a fatal disease lacking standardized treatment. We describe the use of fast neutron radiation therapy in MPM patients referred to the Department of Radiation Oncology at the University of Washington Medical Center.

Sunday 24th July 1154

Formation and characterization of hypermineralized zone beneath dentine lesion body induced by topical fluoride in-vitro.

This in-vitro study aimed to evaluate and characterize the hypermineralized zone (Hyper-zone) formed beneath the remineralized dentine lesion body by transverse microradiography (TMR), scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDS).

Tuesday 5th July 1154

Frontiers in Male Contraception: There are few alternatives now, but several promising avenues of research are under way.

On the female side, when it comes to contraception, there's an arsenal of options. There's the pill, patches, implants, injectable hormones, sponges, spermicides, cervical caps, diaphragms, morning-after pills, and the intrauterine device.

Friday 24th June 1154

From Dissertation Defense to Dissemination: Jump Start Your Academic Career With a Scholar Mentor Group.

The dissertation provides an excellent source of scholarly productivity for new doctoral faculty, yet is often neglected because of the demands inherent in the faculty role.

Friday 22nd April 1154

Functionalization of quantum rods with oligonucleotides for programmable assembly with DNA origami.

The DNA-mediated self-assembly of CdSe/CdS quantum rods (QRs) onto DNA origami is described. Two QR types with unique optical emission and high polarization were synthesized, and then functionalized with oligonucleotides (ssDNA) using a novel protection-deprotection approach, which harnessed ssDNA's tailorable rigidity and denaturation temperature to increase DNA coverage by reducing non-specific coordination and wrapping. The QR assembly was programmable, and occurred at two different assembly zones that h...

Tuesday 1st March 1154

Functional Outcomes of Simultaneous Bilateral Versus Unilateral Total Knee Arthroplasty.

Many patients in need of total knee arthroplasty (TKA) have bilateral symptoms and require surgery to both extremities. Performance of a bilateral procedure under a single anesthetic provides a reduced hospitalization time, an isolated anesthesia risk, a single rehabilitation, and substantial cost savings. While most current research examines postoperative complication rates, the primary purpose of TKA is the alleviation of pain and improved quality of life. The purpose of this study was to assess pain and ...

Tuesday 1st February 1154

From the Literature.

Thursday 20th January 1154

Five new cases of breast cancer in transsexual persons.

Cross-sex hormone treatment of transsexual people may be associated with the induction and growth stimulation of hormone-related malignancies. We report here five cases of breast cancer, three in female-to-male (FtoM) transsexual subjects and two in male-to-female (MtoF) transsexual subjects. In the general population the incidence of breast cancer increases with age and with duration of exposure to sex hormones. This pattern was not recognised in these five transsexual subjects. Tumours occurred at a relat...

1153987

Factors that influence the generation of autobiographical memory conjunction errors.

The constructive nature of memory is generally adaptive, allowing us to efficiently store, process and learn from life events, and simulate future scenarios to prepare ourselves for what may come. However, the cost of a flexibly constructive memory system is the occasional conjunction error, whereby the components of an event are authentic, but the combination of those components is false. Using a novel recombination paradigm, it was demonstrated that details from one autobiographical memory (AM) may be inc...

1153915

Fruit Extract from A Sechium edule Hybrid Induce Apoptosis in Leukaemic Cell Lines but not in Normal Cells.

The antiproliferative potential of a crude extract from the chayote hybrid H-837-07-GISeM® and its potential for apoptosis induction were assessed in leukaemic cell lines and normal mouse bone marrow mononuclear cells (BM-MNCs). The extract strongly inhibited the proliferation of the P388, J774, and WEHI-3 cell lines (with an IC50 below 1.3 μg·mL(-1)), reduced cell viability, and induced apoptotic body production, phosphatidylserine translocation, and DNA fragmentation. However, the extract had no effec...

1153886

Forecasted coral reef decline in marine biodiversity hotspots under climate change.

Coral bleaching events threaten coral reef habitats globally and cause severe declines of local biodiversity and productivity. Related to high sea surface temperatures, bleaching events are expected to increase as a consequence of future global warming. However, response to climate change is still uncertain as future low latitude climatic conditions have no present-day analogue. Sea surface temperatures during the Eocene epoch were warmer than forecasted changes for the coming century, and distributions of ...

1153837

Figuier's Forlorn Figure: Horace Wells and the "Humbug Affair"

1153814

Facile synthesis of zwitterionic polymer-coated core-shell magnetic nanoparticles for highly specific capture of N-linked glycopeptides.

Highly selective and efficient capture of glycosylated proteins and peptides from complex biological samples is of profound significance for the discovery of disease biomarkers in biological systems. Recently, hydrophilic interaction liquid chromatography (HILIC)-based functional materials have been extensively utilized for glycopeptide enrichment. However, the low amount of immobilized hydrophilic groups on the affinity material has limited its specificity, detection sensitivity and binding capacity in the...

1153746

Freestanding polyaniline nanorods grown on graphene for highly capacitive energy storage.

Freestanding polyaniline (PANI) nanorods grown in situ on microwave-expanded graphene oxide (MEGO) sheets were prepared through a facile solution method. The morphological characterization indicates that large quantity of free-standing PANI nanorods with average diameter of 50 nm were uniformly deposited onto the double sides of the MEGO nanosheets to form a sandwich structure. The hybrid of PANI/MEGO (GPANI) exhibit high specific surface area and high electrical conductivity, compared with pristine PANI na...


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