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22:19 EDT 22nd October 2014 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 51–75 of 927


Yield-Enhancing Heterotic QTL Transferred from Wild Species to Cultivated Rice Oryza sativa L.

Utilization of "hidden genes" from wild species has emerged as a novel option for enrichment of genetic diversity for productivity traits. In rice we have generated more than 2000 lines having introgression from 'A' genome-donor wild species of rice in the genetic background of popular varieties PR114 and Pusa44 were developed. Out of these, based on agronomic acceptability, 318 lines were used for developing rice hybrids to assess the effect of introgressions in heterozygous state. These introgression line...

Wednesday 11th March 1034

Young Adults, Social Networks, and Addiction Recovery: Post Treatment Changes in Social Ties and Their Role as a Mediator of 12-Step Participation.

Social factors play a key role in addiction recovery. Research with adults indicates individuals with substance use disorder (SUD) benefit from mutual-help organizations (MHOs), such as Alcoholics Anonymous, via their ability to facilitate adaptive network changes. Given the lower prevalence of sobriety-conducive, and sobriety-supportive, social contexts in the general population during the life-stage of young adulthood, however, 12-step MHOs may play an even more crucial recovery-supportive social role for...


Yanagihara Facial Nerve Grading System as a Prognostic Tool in Bell's Palsy.

The aim of this study was to evaluate the accuracy of the Yanagihara facial nerve grading system in assessing the course of recovery and in determining the probability of a complete recovery of Bell's palsy within 1 week after onset.


Yellowing and bleaching of grey hair caused by photo and thermal degradation.

Yellowing is an undesirable phenomenon that is common in people with white and grey hair. Because white hair has no melanin, the pigment responsible for hair colour, the effects of photodegradation are more visible in this type of hair. The origin of yellowing and its relation to photodegradation processes are not properly established, and many questions remain open in this field. In this work, the photodegradation of grey hair was investigated as a function of the wavelength of incident radiation, and its ...


Yeast cell lysis enhances dimethyl trisulfide formation in sake.

The present study showed that the lysis of yeast cells and subsequent release of cell contents in sake mash accelerated dimethyl trisulfide (DMTS) formation. Among these, heat unstable and relatively high molecular weight compounds were assumed to be enzymes; thus, enzymatic reactions probably contribute to DMTS formation.


You Keep Using That Term.

Monday 22nd August 1030

Yielding to Desire: The Durability of Affective Preferences.

People's expectations about the future are guided not just by the contingencies of situations but also by what they hope or wish will happen next. These preferences can inform predictions that run counter to what should or must occur based on the logic of unfolding events. Effects of this type have been regularly identified in studies of judgment and decision making, with individuals' choices often reflecting emotional rather than rational influences. Encouraging individuals to rely less on their emotional ...


Yes! Sex Matters: Sex, the Brain and Blood Pressure.

The role of the brain in hypertension between the sexes is known to be important especially with regards to the effects of circulating sex hormones. A number of different brain regions important for regulation of sympathetic outflow and blood pressure express estrogen receptors (ERα and ERβ). Estradiol, acting predominantly via the ERα, inhibits angiotensin II activation of the area postrema and subfornical organ neurons and inhibits reactive oxygen generation that is required for the development of Angi...

Saturday 11th January 1028

Younger age at the time of first metastasis in BRAF-mutated compared to BRAF wild-type melanoma patients.

The relationship between BRAF mutations and the patient clinical profile is still under question. The objective of the present study was to correlate the BRAF mutation status in primary and metastatic melanomas with the clinicopathological profile, disease-free (DFS) and overall survival (OS). A total of 367 melanoma samples from 278 patients were screened for their BRAF status using a combination of allele-specific amplification and DNA sequencing. Two or three tissue samples from the same patient were ava...


Yellow/orange emissive heavy-metal complexes as phosphors in monochromatic and white organic light-emitting devices.

Owing to the electron spin-orbit coupling (SOC) and fast intersystem crossing (ISC), heavy-metal complexes (such as iridium(iii), platinum(ii) and osmium(ii) complexes, etc.) are phosphorescent emitters at room temperature. Since 1998, heavy-metal complexes as phosphors have received considerable academic and industrial attention in the field of organic light-emitting diodes (OLEDs), because they can harvest both the singlet (25%) and triplet (75%) excitons for emission during the electro-generated processe...

Monday 18th March 1027

Ytterbium-doped large-mode-area silica fiber fabricated by using chelate precursor doping technique.

We reported on a highly effective chelate precursor doping technique for Yb-doped large-mode-area (LMA) fiber manufacture. By accurately controlling the evaporation temperature and flow rate of carrier gas, the chelate precursor doping technique is capable of making Yb-doped LMA silica fiber with good uniformity free of center dip, low numerical aperture of ∼0.056, large preform core size of 4.46 mm, and appropriate cladding absorption of 1.17  dB/m at 976.4 nm. Based on a single-end-pump all-fiber ...


You are what you eat: Gut microbiota determines kin recognition in Drosophila.

Gut bacteria is now considered as an additional host organ, and it has been shown that they have important influences on host developmental and physiological processes. More recently gut bacteria have additionally been implicated in behavioral processes. We showed that in two species of Drosophila, gut bacteria variation affects behavior, altering partner investment in copulation in relation to whether individuals were familiar (i.e., having developed in the same environment), or were related. This suggests...


YIA1 Early Detection of the Process of Vascular Calcification with Spect-ct and Pet-ct using Novel Bone Seeking Radiopharmaceuticals in Rat Models.

Vascular calcification is considered to be a significant predictor of coronary heart disease. It is also associated with serious clinical complications such as left ventricular hypertrophy and calcific uremic arteriolopathy. Matrix vesicles and apoptotic bodies (AB's) released by calcifying vascular smooth muscle cells (VSMC's) form the nidus for calcification in the vessel wall. Electron beam computed tomography (EBCT), the gold standard for non-invasive imaging and quantitation of vascular calcification f...


YIA2 PMCA1 Deletion Leads to Increased Blood Pressure and Cardiac Hypertrophy.

Heart failure is the common and final end point of cardiovascular disease. Seventy four percent of congestive heart failure patients also suffer from hypertension. Genome wide association studies (GWAS) have recently identified mutations in the ATP2B1 gene as having a strong association with hypertension risk. The ATP2B1 gene encodes the calcium extrusion pump, plasma membrane calcium ATPase (PMCA1), which also functions as a signalling molecule. This project aims to examine the link between PMCA1 and blood...


YIA4 Genetic Risk Markers for Atrial Fibrillation Influence Allelic Expression of Nearby Candidate Genes.

: Genome-wide association studies (GWAS) have identified genetic variants in nine chromosomal regions that are associated with atrial fibrillation (AF). The mechanisms underlying these associations are unknown. To investigate these mechanisms, we mapped associations between single nucleotide polymorphisms (SNPs) and allelic expression of candidate genes in the region of interest.


YIA5 RGS-1 Regulates Leukocyte Trafficking in Atherosclerosis and Aortic Aneurysm Formation through Chemokine Receptor Desensitisation.

: The regulation of macrophage recruitment and retention into the vascular wall is critical in the progression of atherosclerosis and aortic aneurysm formation. This can be mediated by chemokine activation of multiple G-protein coupled receptors. The Regulator of G-Protein Signalling-1 (RGS-1) acts to deactivate the intracellular response to sustained chemokine stimulation. We have found that RGS-1 is up-regulated with atherosclerotic plaque progression and with monocyte-macrophage activation. However littl...

Friday 13th April 1026

Yolk Sac Mesenchymal Progenitor Cells from New World Mice (Necromys lasiurus) with Multipotent Differential Potential.

Fetal membranes are abundant, ethically acceptable and readily accessible sources of stem cells. In particular, the yolk sac is a source of cell lineages that do not express MHCs and are mainly free from immunological incompatibles when transferred to a recipient. Although data are available especially for hematopoietic stem cells in mice and human, whereas other cell types and species are dramatically underrepresented. Here we studied the nature and differentiation potential of yolk sac derived mesenchymal...


Youth Risk Behavior Surveillance - United States, 2013.

Problem: Priority health-risk behaviors contribute to the leading causes of morbidity and mortality among youth and adults. Population-based data on these behaviors at the national, state, and local levels can help monitor the effectiveness of public health interventions designed to protect and promote the health of youth nationwide. Reporting Period Covered: September 2012-December 2013. Description of the System: The Youth Risk Behavior Surveillance System (YRBSS) monitors six categories of priority healt...

Tuesday 28th March 1025

Youth marijuana use: state of the science for the practicing clinician.

Despite widespread marijuana use among adolescents, accurate information on known health effects is poorly disseminated to clinicians and their patients. Amidst rapidly evolving drug policy in the United States and elsewhere, it is imperative that providers understand the short-term and long-term consequences of marijuana use.


Yacon (Smallanthus Sonchifolius): a food with multiple functions.

Abstract Functional foods are the focus of many studies worldwide. This is justified by the effects they have on public health and thus interest in elucidation of the mechanisms involved in their actions. The present review aims to broaden the discussions of the functional properties attributed to yacon (Smallanthus sonchifolius), considered a food with multiple functions since it possesses bioactive compounds (antimicrobial, antioxidant and probiotic substances) that exert beneficial effects on the body. A...


Young Children's Understanding of Denial.

Although a fair amount is known about young children's production of negation, little is known about their comprehension. Here, we focus on arguably the most complex basic form, denial, and how young children understand denial, when it is expressed in response to a question with gesture, single word, or sentence. One hundred twenty-six children in 3 age groups (Ms = 1 year 9 months, 2 years 0 months, and 2 years 4 months) witnessed an adult look into 1 of 2 buckets and then, in response to a question about ...


Young Workers' Abilities to Self-report Agricultural Work Experience and Occupational Injuries Using Daily Diaries.

Tuesday 15th December 1023

Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis.

Organogenesis of the testis is initiated when expression of Sry in pre-Sertoli cells directs the gonad toward a male-specific fate. The cells in the early bipotential gonad undergo de novo organization to form testis cords that enclose germ cells inside tubules lined by epithelial Sertoli cells. Although Sertoli cells are a driving force in the de novo formation of testis cords, recent studies in mouse showed that reorganization of the vasculature and of interstitial cells also play critical roles in testis...

Thursday 30th April 1023

Youth varicocele and varicocele treatment: a meta-analysis of semen outcomes.

To study youth who have a varicocele or are undergoing varicocele treatment, in relation to changes in semen, as measured by semen analysis (SA).


Yeast Two-Hybrid System for Dissecting the Rice MAPK Interactome.

Protein-protein interactions are a preliminary but fundamental key to many biological systems. Identification of proteins that interact with particular bait not only contributes to a deeper understanding of bait protein function but also provides much information for the discovery of larger-scale interaction networks (interactome). Therefore, protein-protein interaction mapping is regarded as a widely accepted standardized functional genomics technique that provides comprehensive functional interpretation o...

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