PubMed Journal Database - Page: 3 RSS

21:52 EDT 24th April 2015 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 51–75 of 1,000+


Young Adult Kidney Transplant Recipients: Nonadherent and Happy.

The aim of this study was to investigate (a) the extent to which age at first renal replacement therapy, achievement of developmental milestones, satisfaction of psychological needs, and coping were related to subjective well-being and medication adherence among young adult kidney transplant recipients; and (b) the relationship between subjective well-being and immunosuppressive medication adherence.


Yinghao Sun: leader of research on prostate cancer in China.


Youth and Parent Measures of Self-Efficacy for Continuous Glucose Monitoring: Survey Psychometric Properties.

Background: This study aimed to describe the development and psychometric evaluation of novel youth and parent measures of self-efficacy related to continuous glucose monitoring (CGM) in pediatric patients with type 1 diabetes. This evaluation also assessed the predictive validity of the CGM Self-Efficacy (CGM-SE) surveys on CGM use and hemoglobin A1c (HbA1c) levels. Subjects and Methods: Study participants included 120 youth with type 1 diabetes for ≥1 year enrolled in a 2-year randomized clinical trial ...

Monday 20th January 1174

Yacon-Based Product in the Modulation of Intestinal Constipation.

This study aimed to assess the effects of a yacon-based product (YBP) on constipation in adults, including the elderly. Forty-eight individuals were recruited and divided into equal intervention groups named the test and control groups. The YBP (test) and the control (maltodextrin) were dissolved in commercial orange juice. The volunteers for the YBP/test group consumed, on a daily basis, orange juice containing 10 g fructooligosaccharide (FOS)/inulin per day. The control group consumed, on a daily basis,...


Yaws Eradication - A Goal Finally within Reach.

Sustained implementation of mass treatment with oral azithromycin followed by active surveillance and targeted treatment of symptomatic and latent yaws, particularly in children, should lead to yaws eradication - though several challenges remain.


Yap/Taz gets under your skin.

During development, neurulation results in formation of both the neural tube and a population of neural crest cells that contribute to a variety of organs including the formation of pigment cells. This emergence of melanocytes from the neural crest involves Pax3-mediated regulation of Mitf and may be similar to the roles these transcriptional regulators play in growth and migration of melanoma cells. Recently, Manderfield et al (2014) have uncovered that Mitf expression is also dependent on the hippo tumou...


Young woman with a four-year history of epilepsy and progressive focal cortical atrophy - What is the diagnosis?

The pathogenesis of disease progression in drug-refractory epilepsy is poorly understood. We report the case of a young woman with a four-year history of epilepsy that progressed rapidly as evidenced by the development of progressive focal cortical atrophy. She underwent biopsy that showed perinatal ischemia and a prominent inflammatory response, including T-cell infiltration and microglial activation. There was no consensus reached on the final diagnosis although the hypothesis of dual pathology (adult var...


Yet Another Empty Forest: Considering the Conservation Value of a Recently Established Tropical Nature Reserve.

The primary approach used to conserve tropical biodiversity is in the establishment of protected areas. However, many tropical nature reserves are performing poorly and interventions in the broader landscape may be essential for conserving biodiversity both within reserves and at large. Between October 2010 and 2012, we conducted bird surveys in and around a recently established nature reserve in Xishuangbanna, China. We constructed a checklist of observed species, previously recorded species, and species i...

Monday 20th February 1166

Yeast Phenomics: An Experimental Approach for Modeling Gene Interaction Networks that Buffer Disease.

The genome project increased appreciation of genetic complexity underlying disease phenotypes: many genes contribute each phenotype and each gene contributes multiple phenotypes. The aspiration of predicting common disease in individuals has evolved from seeking primary loci to marginal risk assignments based on many genes. Genetic interaction, defined as contributions to a phenotype that are dependent upon particular digenic allele combinations, could improve prediction of phenotype from complex genotype, ...

Friday 3rd June 1165

Youden's Index and the Weight of Evidence.

By means of Shannon's relationship between information and probability, Youden's index for rating diagnostic tests is shown to be a probability-scale analogue of the log-likelihood ratio of a positive test outcome.

Wednesday 22nd September 1164

Yeast Prions: Proteins Templating Conformation and an Anti-prion System.


Your Diabetes Care Provider in the Future Is Probably an NP or PA!

Wednesday 29th May 1162

Youth Tobacco Product Use in the United States.

Noncigarette tobacco products are increasingly popular among youth, especially cigarette smokers. Understanding multiple tobacco product use is necessary to assess the effects of tobacco products on population health. This study examines multiple tobacco product use and associated risk factors among US youth.

Monday 7th December 1158

YAP Regulates S-Phase Entry in Endothelial Cells.

The Hippo pathway regulates cell proliferation and apoptosis through the Yes-associated protein (YAP) transcriptional activator. YAP has a well-described role in promoting cell proliferation and survival, but the precise mechanisms and transcriptional targets that underlie these properties are still unclear and likely context-dependent. We found, using siRNA-mediated knockdown, that YAP is required for proliferation in endothelial cells but not HeLa cells. Specifically, YAP is required for S-phase entry and...


Yeast population dynamics during prefermentative cold soak of Cabernet Sauvignon and Malbec wines.

Prefermentative cold soak is a widely used technique in red wine production, but the impact on the development of native yeast species is hardly described. The aim of this work was to analyse the dynamics and diversity of yeast populations during prefermentative cold soak in red wines. Three different temperatures (14±1°C; 8±1°C and 2.5±1°C) were used for prefermentative cold soak in Cabernet Sauvignon and Malbec grape musts. Saccharomyces and non-Saccharomyces populations during cold soak and alcohol...


Youth offspring of mothers with posttraumatic stress disorder have altered stress reactivity in response to a laboratory stressor.

Parental Posttraumatic Stress Disorder (PTSD), particularly maternal PTSD, confers risk for stress-related psychopathology among offspring. Altered hypothalamic-pituitary-adrenal (HPA) axis functioning is one mechanism proposed to explain transmission of this intergenerational risk. Investigation of this mechanism has been largely limited to general stress response (e.g., diurnal cortisol), rather than reactivity in response to an acute stressor. We examined cortisol reactivity in response to a laboratory s...


Yield of Urinary Tract Cancer Diagnosis With Repeat CT Urography in Patients With Hematuria.

OBJECTIVE. The purpose of this study was to evaluate the yield of repeat CT urography (CTU) in detecting urinary tract malignancies in patients with hematuria. MATERIALS AND METHODS. A review of 5525 patients who underwent CTU between 2000 and 2011 revealed 751 (13.6%) patients who underwent repeat CTU. We excluded 127 patients with more than 3 years between examinations, 409 with nonhematuria indications, and 13 with less than 1 year of follow-up from a negative repeat examination. An additional 54 patient...


Yes-associated protein regulates the growth of human non-small cell lung cancer in response to matrix stiffness.

The Yes‑associated protein (YAP) transcriptional coactivator is recognized as a crucial regulator of human cancer. However, its involvement in human non‑small cell lung cancer (NSCLC) in response to physical cues remains unclear. In this study, substrates with different rigidity were generated in order to evaluate the role of YAP, and its upstream regulators in the Hippo pathway, in the regulation of growth of an NSCLC cell line within particular environments. It was shown that the expression of the YAP...

Thursday 18th July 1151

YAF2 promotes TP53-mediated genotoxic stress response via stabilization of PDCD5.

Programmed cell death 5 (PDCD5) plays a crucial role in TP53-mediated apoptosis, but the regulatory mechanism of PDCD5 itself during apoptosis remains obscure. We identified YY1-associated factor 2 (YAF2) as a novel PDCD5-interacting protein in a yeast two-hybrid screen for PDCD5-interacting proteins. We found that YY1-associated factor 2 (YAF2) binds to and increases PDCD5 stability by inhibiting the ubiquitin-dependent proteosomal degradation pathway. However, knocking-down of YAF2 diminishes the levels o...


YAP as oncotarget in uveal melanoma.

Wednesday 8th July 1147

Yogurt Containing the Probacteria Lactobacillus acidophilus Combined with Natural Antioxidants Mitigates Doxorubicin-Induced Cardiomyopathy in Rats.

Probiotics and antioxidants have a definite improving effect in cardiovascular diseases. This study aims at mitigating doxorubicin toxicity on cardiac function through consuming a functional food. Five groups of adult male Sprague-Dawley rats were used along 22 weeks. Group I received 30 g/kg/day food enriched with yogurt, green tea extract, and carrots (80, 0.84, and 100 g/kg diet, respectively) from the first week, group II received carvedilol 30 mg/kg/day orally from week 17, group III received bot...

Sunday 1st March 1147

Young driver licensing: Examination of population-level rates using New Jersey's state licensing database.

Recent surveys have provided insight on the primary reasons why US teens delay licensure but are limited in their ability to estimate licensing rates and trends. State administrative licensing data are the ideal source to provide this information but have not yet been analyzed for this purpose. Our objective was to analyze New Jersey's (NJ) licensing database to: (1) describe population-based rates of licensure among 17- to 20-year-olds, overall and by gender and zip code level indicators of household incom...

Sunday 30th November 1146

You can't say that: using social media in the healthcare setting requires sound judgment.


Young and Midlife Stroke Survivors' Experiences With the Health Services and Long-Term Follow-Up Needs.

The aim of this qualitative study was to explore young and midlife stroke survivors' experiences with the health services and to identify long-term follow-up needs. Sixteen participants from two cohorts were interviewed in-depth. The interviews were analyzed applying a hermeneutic-phenomenological analysis. The participants struggled to gain access to follow-up health services. They felt that whether they were systematically followed up was more coincidental than planned. Young and midlife stroke survivors ...

Sunday 9th October 1143

Your body, my body, our coupling moves our bodies.

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