PubMed Journal Database - Page: 5 RSS

23:29 EDT 24th May 2015 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 101–125 of 34,000+

Friday 21st June 1241

Feasibility and Efficacy of a Self-Management Intervention for Insomnia in Stable Heart Failure.

Chronic insomnia is common among patients with heart failure (HF) and may contribute to fatigue and poor function. However, to date there have been no randomized controlled trials focused on treatment of insomnia or daytime symptoms in this population.

Tuesday 28th May 1241

Filling the Knowledge Gaps.

Monday 27th May 1241

Filling a niche market: administering drugs by injection or infusion.

There is greater incentive than ever to keep individuals requiring injectable or infusion therapy in the nursing facility-and not transfer them to a hospital-to receive those services. There is a demand for pharmacists with the skills, knowledge, and training to provide these services. To make that possible, pharmacies and pharmacists with the proper equipment, supplies, knowledge, training, and expertise are needed to work closely with physicians and nurses to provide sterile, properly compounded products ...

Saturday 20th April 1241

Feasibility of Measuring Ventilatory Threshold in Adults with Stroke-Induced Hemiparesis: Implications for Exercise Prescription.

Assess the feasibility of measuring ventilatory threshold (VT) in adults with walking impairments due to stroke. Secondary objectives: assess reliability of VT over trials; assess whether participants could sustain treadmill walking at VT; compare mean heart rate (HR) during sustained treadmill walking to estimated heart rate reserve (HRR).

Friday 15th March 1241

Frenulectomy of the tongue and the influence of rehabilitation exercises on the sEMG activity of masticatory muscles.

This study aimed to assess by surface electromyography (sEMG) the changes in sub-mental, orbicularis oris, and masticatory muscle activity after a lingual frenulectomy. Rehabilitation exercises in subjects with ankyloglossia, characterized by Class I malocclusion, were assessed as well. A total of 24 subjects were selected. Thirteen subjects (mean age 7±2.5years) with Class I malocclusion and ankyloglossia were treated with lingual frenulectomy and rehabilitation exercises, while 11 subjects (mean age 7±0...

Sunday 17th February 1241

Factors facilitating patient satisfaction among women with medically unexplained long-term fatigue: A relational perspective.

Bodily conditions that are difficult to identify, explain and treat with the aid of medical knowledge and technology appear to be particularly challenging to medical encounters. Patients are often dissatisfied with the help they receive, and they often experience that their medical needs are not met. To explore factors facilitating patient satisfaction among patients with a medically unexplained condition, we ask: what is the importance of individual versus relational factors in facilitating patient satisfa...

Wednesday 16th January 1241

Functional gait outcomes for idiopathic normal pressure hydrocephalus after primary endoscopic third ventriculostomy.

We evaluated if patients with idiopathic normal pressure hydrocephalus (iNPH) showed functional improvement after primary endoscopic third ventriculostomy (ETV). The efficacy of ETV for iNPH remains controversial. We retrospectively reviewed 10 consecutive patients treated between 2009 and 2011 with ETV for iNPH. Seven patients with a median age of 73years (range: 60-80) who underwent a primary ETV for iNPH were included for analysis. Median follow-up was 39months (range: 26-46). Post-ETV stoma and aqueduct...


Field approach to mining-dump revegetation by application of sewage sludge co-compost and a commercial biofertilizer.

An approach was devised for revegetation of a mining dump soil, sited in a semiarid region, with basic pH as well as Fe and Mn enrichment. A field experiment was conducted involving the use of co-compost (a mixture of urban sewage sludge and plant remains) along with a commercial biofertilizer (a gel suspension which contains arbuscular mycorrhizal fungus) to reinforce the benefits of the former. Four treatments were studied: unamended soil; application of conditioners separately and in combination. Pistach...


Freestanding EDs and the Emergency Medicine Resident: A Valuable Part of Resident Education?


Formaldehyde Cross-linking and Structural Proteomics: Bridging the Gap.

Proteins are dynamic entities constantly moving and altering their structures based on their functions and interactions inside and outside the cell. Formaldehyde cross-linking combined with mass spectrometry can accurately captureinteractions of these rapidly changing biomolecules while maintaining their physiological surroundings. Even with its numerous established uses in biology and compatibility with mass spectrometry, formaldehyde has not yet been applied in structural proteomics. However, formaldehyde...


Focal nodular hyperplasia: A diagnosis to consider in a hepatic mass.


From the Editor.


FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production.

The mechanistic links between genetic variation and autoantibody production in autoimmune disease remain obscure. Autoimmune lymphoproliferative syndrome (ALPS) is caused by inactivating mutations in FAS or FASL, with autoantibodies thought to arise through failure of FAS-mediated removal of self-reactive germinal center (GC) B cells. Here we show that FAS is in fact not required for this process. Instead, FAS inactivation led to accumulation of a population of unconventional GC B cells that underwent soma...


Fibrinolysis shutdown phenotype masks changes in rodent coagulation in tissue injury versus hemorrhagic shock.

Systemic hyperfibrinolysis (accelerated clot degradation) and fibrinolysis shutdown (impaired clot degradation) are associated with increased mortality compared with physiologic fibrinolysis after trauma. Animal models have not reproduced these changes. We hypothesize rodents have a shutdown phenotype that require an exogenous profibrinolytic to differentiate mechanisms that promote or inhibit fibrinolysis.


Facial lesions and acute hepatitis in an Human Immunodeficiency Virus infected patient from Paraguay.


Fronto-parietal and cingulo-opercular network integrity and cognition in health and schizophrenia.

Growing evidence suggests that coordinated activity within specific functional brain networks supports cognitive ability, and that abnormalities in brain connectivity may underlie cognitive deficits observed in neuropsychiatric diseases, such as schizophrenia. Two functional networks, the fronto-parietal network (FPN) and cingulo-opercular network (CON), are hypothesized to support top-down control of executive functioning, and have therefore emerged as potential drivers of cognitive impairment in disease-s...


Forecasting carbapenem resistance from antimicrobial consumption surveillance: Lessons learnt from an OXA-48-producing Klebsiella pneumoniae outbreak in a West London renal unit.

This study aimed to forecast the incidence rate of carbapenem resistance and to assess the impact of an antimicrobial stewardship intervention using routine antimicrobial consumption surveillance data. Following an outbreak of OXA-48-producing Klebsiella pneumoniae (January 2008-April 2010) in a renal cohort in London, a forecasting ARIMA model was derived using meropenem consumption data [defined daily dose per 100 occupied bed-days (DDD/100OBD)] from 2005-2014 as a predictor of the incidence rate of OXA-4...


Factor H-related proteins determine complement-activating surfaces.

Complement factor H-related proteins (FHRs) are strongly associated with different diseases involving complement dysregulation, which suggests a major role for these proteins regulating complement activation. Because FHRs are evolutionarily and structurally related to complement inhibitor factor H (FH), the initial assumption was that the FHRs are also negative complement regulators. Whereas weak complement inhibiting activities were originally reported for these molecules, recent developments indicate that...


Foods related to the novel 'don quixote de la mancha'. did they follow the healthy nutritional recommendations which are advised nowadays?

It is known that Miguel de Cervantes's novel 'Don Quixote de La Mancha' has done and is still doing a great contribution to the universal literature. A book that has reached such category and grows in number of its readers, shows multiple dimensions for its study. One of them is nutrition. One of the aims of this study has been to value and expound, according to their own nutrients, the kinds of food cited in 'The Quixote' and in the times of Cervantes. This has allowed the comparison made between ways of n...


Functional pyruvate formate lyase pathway expressed with two different electron donors in Saccharomyces cerevisiae at aerobic growth.

Pyruvate formate lyase (PFL) is characterized as an enzyme functional at anaerobic conditions, since the radical in the enzyme's active form is sensitive to oxygen. In this study, pyruvate formate lyase and its activating enzyme from Escherichia coli were expressed in a Saccharomyces cerevisiae strain lacking pyruvate decarboxylase and having a reduced glucose uptake rate due to a mutation in the transcriptional regulator Mth1, IMI076 (Pdc(-) MTH1-ΔT ura3-52). PFL was expressed with two different electron ...


False positive in the measurement of Thyroglobulin induced by Rheumatoid Factor.

We report a case of interference in thyroglobulin (Tg) measurement in a woman with differentiated thyroid cancer and rheumatoid arthritis history. Due to discordant Tg in relation to TSH concentrations and negative images, we investigated possible interference in the measurement of Tg.


False localizing sign of cervico-thoracic CSF leak in spontaneous intracranial hypotension.

Spontaneous spinal CSF leaks are an important cause of new-onset headaches. Such leaks are reported to be particularly common at the cervico-thoracic junction. The authors undertook a study to determine the significance of these cervico-thoracic CSF leaks.


Fibromyalgia and the Risk of a Subsequent Motor Vehicle Crash.

Motor vehicle crashes are a widespread contributor to mortality and morbidity, sometimes related to medically unfit motorists. We tested whether patients diagnosed with fibromyalgia (FM) have an increased risk of a subsequent serious motor vehicle crash.


FGF2 alleviates PTSD symptoms in rats by restoring GLAST function in astrocytes via the JAK/STAT pathway.

In our previous study, we demonstrated that fibroblast growth factor 2 (FGF2) administration alleviated posttraumatic stress disorder (PTSD) symptoms via an "astrocyte-related" mechanism. We further investigated the changes in the astrocytic glutamate transporters GLAST and GLT-1 and in JAK/STAT3 signaling (which is involved in astrocyte activation and GLAST/GLT-1 function) in single prolonged stress (SPS) model rats. High-performance liquid chromatography (HPLC), Western blot and immunohistochemistry analy...


Fractionation and release behaviors of metals (In, Mo, Sr) from industrial sludge.

Little is known on the fate of rare metals in the environment and the associated risks. The fractionation and release of three metals of an industrial sludge were assessed. The average concentration ranges from 39.3 to 41.5 mg/kg for indium (In), 43.1-77.8 mg/kg for molybdenum (Mo), and 131.1-376.4 mg/kg for strontium (Sr). Sequential extraction results implied that In was mobile, while Mo and Sr were immobile. However, experimental results from effects of Eh/pH revealed that In was slightly mobile under...

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