PubMed Journal Database - Page: 5 RSS

13:47 EDT 5th July 2015 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 101–125 of 35,000+

Monday 30th November 1282

Functional Neuroimaging Distinguishes Posttraumatic Stress Disorder from Traumatic Brain Injury in Focused and Large Community Datasets.

Traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD) are highly heterogeneous and often present with overlapping symptomology, providing challenges in reliable classification and treatment. Single photon emission computed tomography (SPECT) may be advantageous in the diagnostic separation of these disorders when comorbid or clinically indistinct.

Sunday 8th November 1282

Five-year results of a randomized clinical trial of conventional surgery, endovenous laser ablation and ultrasound-guided foam sclerotherapy in patients with great saphenous varicose veins.

A variety of techniques exist for the treatment of patients with great saphenous vein (GSV) varicosities. Few data exist on the long-term outcomes of these interventions.

Sunday 25th October 1282

Fungal Serotype-Specific Differences in Bacterial-Yeast Interactions.

Cryptococcus neoformans (Cn) causes meningoencephalitis in immunocompromised individuals. This encapsulated fungus can be found interacting with environmental microbes in soil contaminated with pigeon excrement. Cn survival within polymicrobial and other challenging communities has been shown to affect the evolution of its virulence factors. We compared the survival of ten serotype A and D strains after interaction with the soil bacterium, Acinetobacter baumannii (Ab). Although co-incubation with Ab stimula...

Sunday 27th September 1282

fMRI Validation of fNIRS Measurements During a Naturalistic Task.

We present a method to compare brain activity recorded with near-infrared spectroscopy (fNIRS) in a dance video game task to that recorded in a reduced version of the task using fMRI (functional magnetic resonance imaging). Recently, it has been shown that fNIRS can accurately record functional brain activities equivalent to those concurrently recorded with functional magnetic resonance imaging for classic psychophysical tasks and simple finger tapping paradigms. However, an often quoted benefit of fNIRS is...

Sunday 26th July 1282

Free Energy Landscapes of Alanine Oligopeptides in Rigid-Body and Hybrid Water Models.

Replica exchange molecular dynamics is used to study the effect of different rigid-body (mTIP3P, TIP4P, SPC/E) and hybrid (H1.56, H3.00) water models on the conformational free energy landscape of the alanine oligopeptides (acAnme and acA5nme), in conjunction with the CHARMM22 force-field. The free energy landscape is mapped out as a function of the Ramachandran angles. In addition, various secondary structure metrics, solvation shell properties and the number of peptide-solvent hydrogen bonds are monitored...

Thursday 11th June 1282

Frequency and characteristics of circulating CD4(+) CD28(null) T cells in patients with psoriasis.

Psoriasis is a chronic inflammatory disease that affects the skin. CD4(+) CD28(null) cells are a subset of T lymphocytes associated with systemic inflammation and increased cardiovascular disease (CVD) risk, and may be involved in the pathogenesis of psoriasis.

Tuesday 9th June 1282

First report of Rhodnius montenegrensis (Hemiptera, Reduviidae, Triatominae) in the State of Acre, Brazil.

This paper reports, for the first time, the presence of Rhodnius montenegrensis in the State of Acre, Brazil.

Wednesday 20th May 1282

Formative Evaluation of a Text Messaging Intervention to Promote Varenicline Adherence Among Tobacco-Dependent Persons with HIV.

Few published studies describe processes in the development of mobile health interventions. This study reports data from a formative evaluation of a text messaging intervention being developed to increase adherence to smoking cessation medication (varenicline) among tobacco-dependent persons with HIV/AIDS. Four focus groups were conducted (N = 29) using a mixed-methods approach to assess: (a) beliefs and preferences regarding the use of varenicline, (b) preferences for receiving tobacco-related texts, and...

Friday 1st May 1282

Family composition and symptom severity among Veterans with comorbid PTSD and substance use disorders.

Posttraumatic stress disorder (PTSD) and substance use disorders (SUD) frequently co-occur and affect a substantial proportion of military Veterans. Although the impact of parental PTSD and SUD on child development is well-documented, little is known about the influence of family composition on PTSD/SUD symptom severity. The present study investigated children in the home as an independent risk factor for symptom severity in a sample of treatment-seeking Veterans (N=94; 92% male) with comorbid PTSD/SUD. Twe...

Tuesday 21st April 1282

Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality.

Viruses often encode proteins with multiple functions due to their compact genomes. Existing approaches to identify functional residues largely rely on sequence conservation analysis. Inferring functional residues from sequence conservation can produce false positives, in which the conserved residues are functionally silent, or false negatives, where functional residues are not identified since they are species-specific and therefore non-conserved. Furthermore, the tedious process of constructing and analyz...

Thursday 16th April 1282

Functional BCL-2 regulatory genetic variants contribute to susceptibility of esophageal squamous cell carcinoma.

B-cell lymphoma-2 (BCL-2) prevents apoptosis and its overexpression could promote cancer cell survival. Multiple functional BCL-2 genetic polymorphisms, such as rs2279115, rs1801018 and rs1564483, have been identified previously and might be involved in cancer development through deregulating BCL-2 expression. Therefore, we examined associations between these three polymorphisms and esophageal squamous cell carcinoma (ESCC) susceptibility as well as its biological function in vivo. Genotypes were determined...

Friday 3rd April 1282

Front cover.

Saturday 21st March 1282

Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization.

Synthetic glycopolymers are instrumental and versatile tools used in various biochemical and biomedical research fields. An example of a facile and efficient synthesis of well-controlled fluorescent statistical glycopolymers using reversible addition-fragmentation chain-transfer (RAFT)-based polymerization is demonstrated. The synthesis starts with the preparation of β-galactose-containing glycomonomer 2-lactobionamidoethyl methacrylamide obtained by reaction of lactobionolactone and N-(2-aminoethyl) metha...

Wednesday 4th March 1282

Fatal Neuroleptic Malignant Syndrome Associated With Quetiapine.

Acute psychosis developed in an elderly patient with Parkinson disease and she was admitted and treated with quetiapine (Seroquel). One day later, high fever unexplained by infection appeared associated with restlessness, confusion, convulsion, leukocytosis, and extreme serum creatine kinase levels. She died of neuroleptic malignant syndrome (NMS) despite intensive treatment. Quetiapine is an atypical neuroleptic agent, rarely associated with NMS in the absence of other contributing drugs. Our case strongly...

Friday 13th February 1282

Far-lateral transcondylar approach for microsurgical trapping of an anterior inferior cerebellar artery aneurysm.

Aneurysms of the posterior circulation remain challenging lesions given their proximity to the brainstem and cranial nerves. Many of these aneurysms may best be approached through a retrosigmoid-suboccipital craniectomy with a far-lateral transcondylar extension. In this narrated video illustration, we present the case of a 37-year-old man with an incidentally discovered right-sided anterior inferior cerebellar artery (AICA) aneurysm. Diagnostic studies included CT angiography and cerebral angiography. A su...

1281995

Functional versus syndromal recovery in patients with major depressive disorder and bipolar disorder.

Many patients with major depressive disorder (MDD) or bipolar disorder (BD) experience impairments in daily life. We investigated whether patients with single-episode MDD (MDD-s), recurrent MDD (MDD-r), and BD differ in functional impairments, whether time since last episode (syndromal state, in 4 categories) contributes to impairment, whether this association is moderated by diagnosis, and the role of depressive symptoms.

1281891

FT overexpression induces precocious flowering and normal reproductive development in Eucalyptus.

Eucalyptus trees are among the most important species for industrial forestry worldwide. However, as with most forest trees, flowering does not begin for one to several years after planting which can limit the rate of conventional and molecular breeding. To speed flowering, we transformed a Eucalyptus grandis × urophylla hybrid (SP7) with a variety of constructs that enable overexpression of FLOWERING LOCUS T (FT). We found that FT expression led to very early flowering, with events showing floral buds w...

1281874

Functional repair of rat corticospinal tract lesions does not require permanent survival of an immuno-incompatible transplant.

Cell transplantation is one of the most promising strategies for repair of human spinal cord injuries. Animal studies from a number of laboratories have shown that transplantation of olfactory ensheathing cells cultured from biopsies of the olfactory bulb mediate axonal regeneration and re-myelination, and restore lost functions in spinal cord injuries. For translation from small laboratory experimental injuries to the large spinal cord injuries encountered in human patients the numbers of cells which can b...

1281853

Four-component relativistic DFT calculations of (77) Se NMR chemical shifts: A gateway to a reliable computational scheme for the medium-sized organoselenium molecules.

A versatile high-accuracy computational scheme for the (77) Se nuclear magnetic resonance (NMR) chemical shifts of the medium-sized organoselenium compounds is suggested within a framework of a full four-component relativistic density functional theory (DFT). The main accuracy factors (DFT functionals, relativistic geometry, vibrational corrections, and solvent effects) are addressed. The best result is achieved with NMR-oriented KT2 functional of Keal-Tozer characterized by a fairly small error of only 30 ...

1281747

Fibrosis - A Common Pathway to Organ Injury and Failure.

To the Editor: In their review, Rockey et al. (March 19 issue)(1) do not include drugs as a possible trigger of lung and cardiac fibrosis. A well-recognized cause of pulmonary fibrosis is drugs - in particular, antineoplastic agents such as bleomycin, busulfan, cyclophosphamide, and carmustine.(2) Other drugs, such as nitrofurantoin, amiodarone, procainamide, flecainide, and penicillamine, have also been implicated. The prognosis in patients with fibrosis induced by alkylating agents is often poor, and the ...

1281746

Fibrosis - A Common Pathway to Organ Injury and Failure.

To the Editor: In their review, Rockey et al. (March 19 issue)(1) do not include drugs as a possible trigger of lung and cardiac fibrosis. A well-recognized cause of pulmonary fibrosis is drugs - in particular, antineoplastic agents such as bleomycin, busulfan, cyclophosphamide, and carmustine.(2) Other drugs, such as nitrofurantoin, amiodarone, procainamide, flecainide, and penicillamine, have also been implicated. The prognosis in patients with fibrosis induced by alkylating agents is often poor, and the ...

1281745

Fibrosis - A Common Pathway to Organ Injury and Failure.

To the Editor: In their review, Rockey et al. (March 19 issue)(1) do not include drugs as a possible trigger of lung and cardiac fibrosis. A well-recognized cause of pulmonary fibrosis is drugs - in particular, antineoplastic agents such as bleomycin, busulfan, cyclophosphamide, and carmustine.(2) Other drugs, such as nitrofurantoin, amiodarone, procainamide, flecainide, and penicillamine, have also been implicated. The prognosis in patients with fibrosis induced by alkylating agents is often poor, and the ...

1281732

FLAMSA reduced-intensity conditioning is equally effective in AML patients with primary induction failure as well as in first or second complete remission.

Reduced intensity conditioning regimens have demonstrated lower toxicity but increased relapse rates in the context of allogeneic haematopoietic stem cell transplantation (aSCT) for patients with acute myelogenous leukaemia (AML). The FLAMSA-RIC regimen, combining a cytoreductive and a transplant-conditioning part, has been described to be efficacious in patients with refractory disease. We retrospectively analysed clinical data of 130 patients with AML after aSCT following FLAMSA conditioning at our center...

1281727

Failure of sugammadex to reverse rocuronium-induced neuromuscular blockade: Simply an outlier or are we missing something?

1281713

Factors Associated with Incomplete Bladder Emptying in Older Women with Overactive Bladder Symptoms.

To identify factors associated with incomplete bladder emptying in older women with overactive bladder (OAB) symptoms.



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