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The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and books. BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.
For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.
In order to promote imaging-guided chemotherapy for preclinical and clinical applications, endogenous nanosystems with both contrast and drug-delivery properties are highly desired. Here, the simple use of melanin is first reported, and this biopolymer with good biocompatibility and biodegradability, binding ability to drugs and ions, and intrinsic photoacoustic properties, can serve as an efficient endogenous nanosystem for imaging-guided tumor chemotherapy in living mice.
Ultrathin and dense metal oxide gate di-electric layers are reported by a simple printing of AlOx and HfOx sol-gel precursors. Large-area printed indium gallium zinc oxide (IGZO) thin-film transistor arrays, which exhibit mobilities >5 cm(2) V(-1) s(-1) and gate leakage current of 10(-9) A cm(-2) at a very low operation voltage of 2 V, are demonstrated by continuous simple bar-coated processes.
Freestanding ultrathin metallic nanosheets (FUMNSs) with atomic thickness attract extensive attention because they display remarkable advantages over their bulk counterparts by virtue of their large specific area, high aspect ratio, and unsaturated surface coordination. The state of the art of research on FUMNSs is reviewed here, wherein the important progress from the aspects of material category, synthetic strategy, and practical application are introduced, and it is demonstrated that FUMNSs will play an ...
Their chemical stability, high specific surface area, and electric conductivity enable porous carbon materials to be the most commonly used electrode materials for electrochemical capacitors (also known as supercapacitors). To further increase the energy and power density, engineering of the pore structures with a higher electrochemical accessible surface area, faster ion-transport path and a more-robust interface with the electrolyte is widely investigated. Compared with traditional porous carbons, two-dim...
By introducing a capping step and controlling reaction parameters, the assembly of metallic nanoparticle aggregates can be achieved using a small molecule crosslinker. Aggregates can be assembled from particles of varied size and composition and the size of the aggregates can be systematically adjusted. Following cell uptake of 60 nm aggregates, the aggregates are stable and nontoxic to macrophage cells up to 55 × 10(-3) m Au.
Diisobutylammonium bromide is found to be a unique improper ferroelastic in which the elastic degrees of freedom seem to play the essential role, giving a rise to a domain pattern resembling that of martensitic phase transitions. A weak canted ferroelectricity turns out switchable by an electric field.
Hemiaminal poly(ethylene glycol) (PEG)-based organogels are formulated in polymerizable solvents. The dynamic-covalent nature of the solvent-H-bonded hemiaminal crosslinks, together with the modification of the crosslinking density of the organogels allows for temperature-dependent viscoelastic control. The shape of uncured gels can be permanently retained by templated UV-curing of the solvent, offering great promise for complex manufacturing, printing, sealants, and materials repair.
Cd(2+) causes deep traps on the surface of CdTe quantum dots (QDs) often leading to a long response time for a photodetector. Poly(3-hexylthiophene) (P3HT) can be used to selectively passivate the Cd(2+) related deep traps by forming a Cd-S bond, while maintaining the shallow traps. By tailoring the trap depth of CdTe QDs, a high gain, fast response, and low noise P3HT:CdTe nanocomposite photodetector is achieved.
Bimetallic metal-organic frameworks are rationally synthesized as templates and employed for porous carbons with retained morphology, high graphitization degree, hierarchical porosity, high surface area, CoN x moiety and uniform N/Co dopant by pyrolysis. The optimized carbon with additional phosphorus dopant exhibits excellent electrocatalytic performance for oxygen reduction reaction, which is much better than the benchamark Pt/C in alkaline media.
A new hydrothermally stable Al polycarboxylate metal-organic framework (MOF) based on a heteroatom bio-derived aromatic spacer has been designed through a template-free green synthesis process. It appears that in some test conditions this MOF outperforms the heat reallocation performances of the commercial SAPO-34.
The filament in aAu/Ta2 O5 /Au system is analyzed and determined to be a nanoscaled TaO2-x filament. A shrunken anode localizes the filament formation and the defect boundary leads to faster accumulation of oxygen vacancies. The defect changes the switching domination between electron transport and oxygen vacancy migration. The migration of oxygen vacancies limits the filament dynamics, indicating the crucial role played by oxygen defects.
A superfast actuator based on bilayer fibrous mat shows folding/unfolding and formation of 3D structures in a fraction of a second. The actuation is reversible for many cycles without losing its form and size with unfolding at room temperature and folding above 35 °C. The system is promising for making 3D bioscaffolds, electrodes, and micro-/macroactuators.
Guided growth of horizontally aligned semiconductor nano-wires is a proven promising approach for their large-scale integration into electronic and optoelectronic devices. However, this approach has so far only been demonstrated for semiconductors with bandgap energies in the UV and IR ranges. On page 3999, E. Joselevich and co-workers demonstrate the guided growth of ZnSe nanowires with controlled structure and orientation, and their integration into visible light detectors.
Single-crystalline grains and grain boundaries in an as-grown molybdenum disulfide monolayer are visualized by second-harmonic-generation microscopy. Further statistical analysis reveals that the boundary formation is driven by kinetics, rather than energetics. The method and derived growth mechanism described on page 4069 by S. W. Wu and co-workers can be extended to many other 2D materials and help guide the tailoring or utilization of grain boundaries.
X. Zhao and co-workers develop on page 4035 a new biocompatible hydrogel system that is extremely tough and stretchable and can be 3D printed into complex structures, such as the multilayer mesh shown. Cells encapsulated in the tough and printable hydrogel maintain high viability. 3D-printed structures of the tough hydrogel can sustain high mechanical loads and deformations.
A pure-copper pillar with a height of 860 μm and a width of ca. 5 μm is shown in the inside back cover image. The pillar is printed by C. W. Visser, R. Pohl, and co-workers as described on page 4087, using laser-induced forward transfer (LIFT), in which droplets with a diameter of around 1 μm are ejected and can be stacked to yield pillars, lines, or more-complex shapes. The results show that LIFT allows pure-metal 3D printing in the micrometer-size range, which has been a long-standing challenge. The ed...
Light-Emitting Diodes: Highly Efficient Orange and Red Phosphorescent Organic Light-Emitting Diodes with Low Roll-Off of Efficiency using a Novel Thermally Activated Delayed Fluorescence Material as Host (Adv. Mater. 27/2015).
A novel host material, MTXSFCz, with the thermally actived delayed fluorescent property is reported by Y. Wang, P. Wang, and co-workers on page 4041 for the construction of red and orange phosphorescent organic light-emitting diodes (PHOLEDs) with low efficiency roll-off. The efficient reverse intersystem crossing of the MTXSFCz host from triplet to singlet facilitates the reduction of the triplet density on the host and then diminished triplet-triplet annihilation and triplet-photon annihilation, leading t...
The miniaturization of metal-organic-framework (MOF) crystals to the nanoscale brings enhanced or novel properties and fulfils specific application needs. The focus here is on a kind of nanoMOF with special configurations and outstanding properties - the hollow structure. Firstly recent advances on the synthesis of MOF hollow nanostructures are introduced. Then, a novel approach based on a heterometallic system is highlighted, by which the facile synthesis of well-defined hollow MOF structures with high com...
A plasmonic hybrid having Pd nanoparticles on plasmonic MoO3 -x is developed by a facile solution process, and its plasmonic resonance displays reversible tunability upon oxidation/reduction. Under visible-light irradiation, the Pd/MoO3-x hybrid exhibits plasmon-enhanced catalysis toward H2 evolution from ammonia borane hydrolysis and the Suzuki-Miyaura coupling reaction relative to dark conditions.
The oxygen inhibition of UV curable polymers is exploited in novel technology for the fabrication of patterns and closed devices. Multiscale structures with thicknesses ranging from few micro-meters to millimeters are rapidly fabricated. Multipoly-meric and multifunctional structures are also prepared: adequately choosing the material of each layer, a set of different properties is arranged in the same device.
A new copolymer PM6 based on fluorothienyl-substituted benzodithiophene is synthesized and characterized. The inverted polymer solar cells based on PM6 exhibit excellent performance with Voc of 0.98 V and power conversion efficiency (PCE) of 9.2% for a thin-film thickness of 75 nm. Furthermore, the single-junction semitransparent device shows a high PCE of 5.7%.
Here the direct synthesis of monolayer and multilayer ReS2 by chemical vapor deposition at a low temperature of 450 °C is reported. Detailed characterization of this material is performed using various spectroscopy and microscopy methods. Furthermore initial field effect transistor characteristics are evaluated which highlight the potential in being used as an n-type semiconductor.
Hydrogel microfish featuring biomimetic structures, locomotive capabilities, and functionalized nanoparticles are engineered using a rapid 3D printing platform: microscale continuous -optical printing (μCOP). The 3D-printed -microfish exhibit chemically powered and magnetically guided propulsion, as well as highly efficient detoxification capabilities that highlight the technical versatility of this platform for engineering advanced functional microswimmers for diverse biomedical applications.