PubMed Journal Database | Clinical orthopaedics and related research 
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Showing PubMed Articles 1–25 of 952 from Clinical orthopaedics and related research
Safety in Surgery: The Role for Registries.
Constitutional Varus Does Not Affect Joint Line Orientation in the Coronal Plane.
BACKGROUND: In a previous study, we described the distribution of coronal alignment in a normal asymptomatic population and recognized the occurrence of constitutional varus in one of four individuals. It is important to further investigate the influence of this condition on the joint line orientation and how the latter is affected by the onset and progression of arthritis. QUESTIONS/PURPOSES: The purposes of this study are (1) to describe the distribution of joint line orientation in the coronal plane in t...
Erratum to: Duplicate Submission and Dual Publication: What Is So Wrong With Them?
CORR Insights(®): Is Premorbid Glenoid Anatomy Altered in Patients with Glenohumeral Osteoarthritis?
BACKGROUND: Surgeons have several implant choices when managing Vancouver B2 and B3 periprosthetic fractures about the hip. Few long-term studies have reported outcomes for tapered fluted titanium stems. QUESTIONS/PURPOSES: We determined (1) survival, with femoral revision as the end point, of distal taper stems in the treatment of Vancouver B2 and B3 periprosthetic fractures at our institution, (2) radiographic outcomes, and (3) quality of life and hip function after revision. METHODS: Of the 200 patients...
Loss of SS18-SSX1 Inhibits Viability and Induces Apoptosis in Synovial Sarcoma.
BACKGROUND: Most synovial sarcomas contain a chromosomal translocation t(X;18), which results in the formation of an oncoprotein SS18-SSX critical to the viability of synovial sarcoma. QUESTIONS/PURPOSES: We (1) established and characterized three novel synovial sarcoma cell lines and asked (2) whether inhibition of SS18-SSX1 decreases cell viability in these cell lines; and (3) whether reduction in viability after SS18-SSX1 knockdown is caused by apoptosis. After identifying a specific posttranscriptional...
Everyone (Else) is Conflicted.
How Long Should We Follow Patients With Soft Tissue Sarcomas?
BACKGROUND: Guidelines suggest that followup for low-grade soft tissue sarcomas should be every 3 to 6 months for 2 to 3 years and then annually, and for high-grade sarcomas every 3 to 6 months for 2 to 5 years, then every 6 months for the next 2 years, and then annually. However, there is only very limited evidence to support these strategies. QUESTIONS/PURPOSES: In a population of patients treated surgically for soft tissue sarcomas, we evaluated the (1) timing of diagnosis of local recurrences after sarc...
Risk Factors for Early Revision After Primary Total Hip Arthroplasty in Medicare Patients.
BACKGROUND: Patient, surgeon, health system, and device factors are all known to influence outcomes in THA. However, patient-related factors associated with an increased risk of early failure are poorly understood, particularly in elderly patients. QUESTIONS/PURPOSES: We identified specific demographic and clinical characteristics associated with increased risk of early revision in Medicare patients with THA. METHODS: The Medicare 5% national sample administrative database was used to calculate the relative...
Giants of Orthopaedic Surgery: Masaki Watanabe MD.
BACKGROUND: Acetabular protrusio is an uncommon finding in hip arthritis. Several reconstructive approaches have been used; however the best approach remains undefined. QUESTIONS/PURPOSES: Our purposes in this study were to (1) describe the THA survivorship for protrusio as a function of the acetabular component, (2) evaluate survivorship of the cup as a function of restoration of radiographic hip mechanics and offset, and (3) report the long-term clinical results. METHODS: One hundred twenty-seven patients...
Retrograde Versus Antegrade Intramedullary Nailing of Gunshot Diaphyseal Femur Fractures.
BACKGROUND: The use of retrograde nailing for gunshot wound femur fractures is controversial due to concerns of knee sepsis after this procedure since the knee is entered to introduce the nail into the canal. QUESTIONS/PURPOSES: We compared retrograde and antegrade nailing for gunshot femur fractures to determine whether (1) knee sepsis or other adverse events were more likely to complicate procedures using retrograde nails, (2) there were differences in surgical time or blood loss, and (3) there were diffe...
Emerging Concepts in Slipped Capital Femoral Epiphysis: Editorial Comment.
BACKGROUND: The treatment of displaced, intraarticular calcaneal fractures (DIACFs) remains challenging and the best treatment choices remain controversial. The majority of patients will have some lasting functional restrictions. However, it is unclear which patient- or surgeon-related factors predict long-term function. QUESTIONS/PURPOSES: We determined (1) the impact of patient- and surgeon-related factors on function of patients after internal fixation of DIACFs and (2) whether severity of injury correla...
In Vivo Pilot Study Evaluating the Thumb Carpometacarpal Joint During Circumduction.
BACKGROUND: Analysis of arthrokinematics may have clinical use in the diagnosis of dynamic instability of the thumb and wrist. Recent technological advances allow noninvasive, high-resolution imaging of skeletal (thumb and carpal bones) structures during motion. QUESTIONS/PURPOSES: The primary purpose of this study is to define the arthrokinematics, estimated joint contact patterns, and distribution ratios of the carpometacarpal joint of the thumb using four-dimensional CT (three-dimensional CT + time) and...
BACKGROUND: The use of a highly conforming, anterior-stabilized bearing has been associated with clinical success in a limited number of studies. QUESTIONS/PURPOSES: We compared Knee Society scores, radiographic results, complication rates, and revision rates with the use of anterior-stabilized bearings compared with cruciate-retaining (CR) bearings. METHODS: A series of 382 patients with 468 primary total knee arthroplasties (TKAs) between 2003 and 2008 with minimum 2-year followup were reviewed. Anterior-...
Diagnosis of Periprosthetic Joint Infection: The Threshold for Serological Markers.
BACKGROUND: Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) have recently been suggested as diagnostic criteria for periprosthetic joint infection (PJI) diagnosis. Thresholds for these markers should be reexamined since they have been determined arbitrarily. QUESTIONS/PURPOSES: Based on recently defined criteria for PJI, we determined (1) whether there is a difference in the threshold value of ESR and CRP between hips and knees, (2) whether the threshold value for ESR and CRP should be dif...
Incidence and Risk Factors for Pulmonary Embolism After Primary Musculoskeletal Tumor Surgery.
BACKGROUND: Limited information is available regarding the incidence, risk factors, and optimal prophylaxis in orthopaedic oncology patients, although malignancy and major orthopaedic surgery are associated with an increased pulmonary embolism (PE) risk. QUESTIONS/PURPOSES: We aimed to investigate the incidence of PE after musculoskeletal tumor surgery in Japanese patients and analyze the potential risk factors for PE. METHODS: We retrospectively identified 3750 patients (1981 males, 1769 females) who under...
Does Femoral Neck to Cup Impingement Affect Metal Ion Levels in Hip Resurfacing?
BACKGROUND: Impingement of the femoral neck with the acetabular component after metal-on-metal hip resurfacing arthroplasty (HRA) is a possible cause of edge loading and accelerated bearing wear. No attempt has been made to correlate radiographic impingement signs and blood metal ion levels. QUESTIONS/PURPOSES: We (1) compared serum cobalt (CoS) and chromium (CrS) concentrations between patients with and without radiographic impingement signs treated with unilateral HRA, (2) determined whether divot depth o...
Care of the Professional Athlete: What Standard of Care?
BACKGROUND: Acetabular fractures are rare in children and can be complicated by premature fusion of the triradiate cartilage resulting in secondary acetabular dysplasia. Early recognition and treatment of a physeal bar in this location can be difficult. The purpose of this case report was to investigate whether early intervention could restore acetabular growth and prevent secondary acetabular dysplasia as measured on plain radiographs. CASE DESCRIPTION: We report a series of three patients (3, 4, and 5 yea...
Guest Editorial: Patriots' Day at the Boston Marathon.
Surgical Technique: Tscherne-Johnson Extensile Approach for Tibial Plateau Fractures.
BACKGROUND: The standard approach to lateral tibial plateau fractures involves elevation of the iliotibial band (IT) and anterior tibialis origin in continuity from Gerdy's tubercle and metaphyseal flare. We describe an alternative approach to increase lateral plateau joint exposure and maintain iliotibial band insertion to Gerdy's tubercle. DESCRIPTION OF TECHNIQUE: The approach entails a partial tenotomy of the anterior half of the IT band leaving the posterior IT band insertion attached to Gerdy's tuberc...
