PubMed Journal Database | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment RSS

19:14 EST 4th March 2015 | BioPortfolio

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Showing PubMed Articles 1–25 of 225 from Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment


Set-up of a multivariate approach based on serum biomarkers as an alternative strategy for the screening evaluation of the potential abuse of growth promoters in veal calves.

A chemometric class modelling strategy (unequal dispersed classes - UNEQ) was applied for the first time as a possible screening method to monitor the abuse of growth promoters in veal calves. Five serum biomarkers, known to reflect the exposure to classes of compounds illegally used as growth promoters, were determined from 50 untreated animals in order to design a model of controls, representing veal calves reared under good, safe and highly standardised breeding conditions. The class modelling was applie...


Synthesis, characterization and analytical application of Fe3O4@SiO2@polyaminoquinoline magnetic nanocomposite for the extraction and pre-concentration of Cd(II) and Pb(II) in food samples.

This work describes a novel Fe3O4@SiO2@polyaminoquinoline magnetic nanocomposite and its application in the pre-concentration of Cd(II) and Pb(II) ions. The parameters affecting the pre-concentration procedure were optimised by a Box-Behnken design through response surface methodology. Three variables (extraction time, magnetic sorbent amount, and pH value) were selected as the main factors affecting the sorption step, while four variables (type, volume and concentration of the eluent; and elution time) wer...


Determination of anabolic agents in dietary supplements by liquid chromatography-high resolution mass spectrometry.

A sensitive method for the identification and quantification of anabolic steroids and clenbuterol at trace levels in dietary supplements by liquid chromatography high resolution mass spectrometry (LC-HRMS) in APCI mode using a single stage Orbitrap analyser operating at a resolution power of 100,000 FWHM was developed and validated. One gram of dietary supplement was added with testosterone-d3 as internal standard, dissolved in methanol, evaporated to dryness, diluted in sodium hydroxide solution and extrac...


A rapid liquid chromatography determination of free formaldehyde in cod.

A rapid method for the determination of free formaldehyde in cod is described. It uses a simple water extraction of formaldehyde which is then derivatised with 2,4-dinitrophenylhydrazine (DNPH) to form a sensitive and specific chromophore for HPLC detection. Although this formaldehyde derivative has been widely used in past tissue analysis, this paper describes an improved derivatisation procedure. The formation of the DNPH formaldehyde derivative has been shortened to 2 min and a stabilising buffer has be...

Friday 23rd November 1172

Migration of epoxidised soybean oil from PVC gaskets of commercial lids: simulation of migration under various conditions and screening of food products from Czech markets.

Previous studies have shown that a large number of polyvinylchloride (PVC) lid gaskets exceed the existing migration limits for epoxidised soybean oil (ESBO) and correct prediction of ESBO release into food therefore appears to be a difficult issue. ESBO migration from PVC gaskets of metal closures into food simulants and food products from the Czech market is evaluated during a survey in 2009 and subsequently one in 2012 to assess progress in lid manufacturing and official testing conditions. ESBO migratio...

Monday 20th August 1172

Dietary intake of trace elements by the population of Catalonia (Spain): results from a total diet study.

This study aimed at analysing the concentrations of Al, Ba, Bi, Cu, Cr, Ge, Mn, Mo, Ni, Sb, Se, Sr and Zn in food samples collected in 2008 in Catalonia (Spain). The dietary intake of these 13 trace elements was subsequently estimated by different age-gender groups of the population: children, adolescents, adults, and seniors. In general terms, fish and shellfish, cereals, and pulses were the food groups showing the highest levels for most elements. Higher dietary intakes were associated to male groups (ado...

Tuesday 3rd July 1172

Dietary exposure to organochlorine pesticide residues of the Hong Kong adult population from a total diet study.

Dietary exposure of the Hong Kong adult population to organochlorine pesticide (OCP) residues was estimated using a total diet study (TDS) approach. OCPs listed under the Stockholm Convention as persistent organic pollutants (POPs) including, aldrin, dieldrin, chlordane, chlordecone, dichlorodiphenyltricholroethane (DDT), endosulfan, endrin, heptachlor, hexachlorobenzene (HCB), α-hexachlorocyclohexanes (HCH), β-HCH, lindane, mirex, pentachlorobenzene and toxaphene, were studied. Out of 600 composite sampl...


Determination of quinolones and fluoroquinolones, tetracyclines and sulfonamides in bovine, swine and poultry liver using LC-MS/MS.

Antibacterials are widely used in veterinary medicine. Residues of these drugs can remain in food of animal origin, including bovine liver. This paper describes a fast and simple analytical method for the determination of quinolones and fluoroquinolones, tetracyclines and sulfonamides in bovine liver samples. Deuterated enrofloxacin, sulfapyridine and demeclocycline were used as internal standards. The homogenised liver samples were extracted with acidified acetonitrile. Steps of non-solid-phase extraction ...


Dietary exposure to benzoates (E210-E213), parabens (E214-E219), nitrites (E249-E250), nitrates (E251-E252), BHA (E320), BHT (E321) and aspartame (E951) in children less than 3 years old in France.

This study aimed to estimate the exposure to seven additives (benzoates, parabens, nitrites, nitrates, BHA, BHT and aspartame) in children aged less than 3 years old in France. A conservative approach, combining individual consumption data with maximum permitted levels, was carried out for all the additives. More refined estimates using occurrence data obtained from products' labels (collected by the French Observatory of Food Quality) were conducted for those additives that exceeded the acceptable daily i...


Isolation and full characterization of a potentially allergenic lipid transfer protein (LTP) protein in almond.

Non-specific Lipid Transfer Proteins (nsLTP) were shown to be among the most significant allergens, in particular in several fruit belonging to the Rosaceae family. The molecular features of LTPs, such as the presence of eight cysteine residues forming four disulfide bridges, confer a compact structure, decreasing the probability of degradation due to cooking or digestion, thereby increasing the chance of systemic absorption and severe allergic reactions. Few studies on LTP-induced allergies regarding almon...


Occurrence of biogenic amines in beers produced with malted organic Emmer wheat (Triticum dicoccum).

Because several groups of microorganisms are able to decarboxylate amino acids, the presence of biogenic amines (BA) can be seen as an index of the microbiological quality of the brewing process. BA were quantified for the first time in the intermediate products and in craft beers produced with malted organic Emmer wheat in a small size brewery, in order to assess the possible presence of critical control points related to biological hazard in the brewing process. BA levels in beers produced exclusively fro...

Tuesday 24th February 1164

Photoinitiators: a food safety review.

UV printing inks are considered safer than the classical inks; however, despite being on the outer surface of the packaging material, their components can migrate into foodstuffs and can give rise to contamination. Photoinitiators are a part of the formulation of printing inks, being an important class of migrant, for which there have been more than 100 incidents of contamination of packaged food with photoinitiators reported through RASFF (Rapid Alert System for Food and Feed) alerts in the EU. In this rev...

Thursday 29th February 1156

Determination of heavy metal ions in vegetable samples using a magnetic metal-organic framework nanocomposite sorbent.

This work describes the synthesis and application of a novel magnetic metal-organic framework (MOF) [(Fe3O4-benzoyl isothiocyanate)/Cu3(benzene-1,3,5-tricarboxylate)2] to pre-concentrate trace amounts of Cd(II), Pb(II), Zn(II) and Cr(III) ions and their determination by flame atomic absorption spectrometry. A Box-Behnken design was used to find the parameters affecting the pre-concentration procedure through response surface methodology. Three factors including uptake time, amount of the magnetic sorbent, a...

Friday 28th July 1155

Determination of synthetic phenolic antioxidants in soft drinks by stir bar sorptive extraction coupled to gas chromatography-mass spectrometry.

The synthetic phenolic antioxidants, butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and tert-butyl hydroquinone (TBHQ), have been pre-concentrated by stir bar sorptive extraction and thermally desorbed (SBSE-TD) before analysis by GC-MS. Several parameters affecting the derivatisation step and both SBSE extraction and thermal desorption were carefully optimised. When the analyses of BHA and TBHQ in their acetylated, silylated and underivatised forms were compared, the best results were obtai...


Evidence of waste electrical and electronic equipment (WEEE) relevant substances in polymeric food-contact articles sold on the European market.

In order to confirm the possibility that recycled fractions from the Waste Electrical and Electronic Equipment (WEEE) stream were illegally entering the European market in black polymeric food-contact articles (FCAs), bromine quantification, brominated flame retardant (BFR) identification combined with WEEE relevant elemental analysis and polymer impurity analysis were performed. From the 10 selected FCAs, seven samples contained a bromine level ranging from 57 till 5975 mg kg(-1) which is lower than expe...

Monday 26th November 1150

Physiological behaviour of gliotoxigenic Aspergillus fumigatus sensu stricto isolated from maize silage under simulated environmental conditions.

Environmental conditions play a key role in fungal development. During the silage production process, humidity, oxygen availability and pH vary among lactic-fermentation phases and among different silage sections. The aim of this work was to study the physiological behaviour of gliotoxicogenic Aspergillus fumigatus strains isolated from maize silage under simulated natural physicochemical conditions - different water activities (aW), temperatures (Tº), pH and oxygen pressure - on the growth parameters (gro...


Mycotoxin production capability of Penicillium roqueforti in strains isolated from mould-ripened traditional Turkish civil cheese.

Mould-ripened civil is a traditional cheese produced mainly in eastern Turkey. The cheese is produced with a mixture of civil and whey curd cheeses (lor). This mixture is pressed into goat skins or plastic bags and is ripened for more than three months. Naturally occurring moulds grow on the surface and inside of the cheese during ripening. In this research, 140 Penicillium roqueforti strains were isolated from 41 samples of mould-ripened civil cheese collected from Erzurum and around towns in eastern Turke...

Tuesday 15th June 1142

Deposition and depletion of maduramicin residues in eggs after oral administration to laying hens determined by liquid chromatography mass spectrometry.

The coccidiostat maduramicin has been approved as a feed additive for chickens and turkeys, although it is prohibited for use in laying hens. In the present study, laying hens were divided into three groups and fed for 14 days with medicated feed containing maduramicin, at three different concentrations: 50, 100 and 500 µg kg(-1). Eggs were collected during treatment and for 26 days after the end of feeding with medicated feed. Maduramicin residues were found exclusively in egg yolk, with the highest conce...

Friday 5th February 1142

Retrospective analysis for the identification of 4-aminocarminic acid photodegradation products in beverages.

This article deals with the identification of the photodegradation products of 4-aminocarminic acid potentially present in commercial beverages. Sixteen beverages of different composition but all containing the E120 dye were previously analysed by ultra-HPLC coupled with quadrupole-time of flight mass spectrometry to identify the common degradation products of the E120 dye. Since it is plausible to find unauthorised 4-aminocarminic acid in beverages which report generic E120 dye on the label, retrospective ...


Pyrazolopyrimidines in 'all-natural' products for erectile dysfunction treatment: the unreliable quality of dietary supplements.

A herbal food supplement advertised as a potency pill was screened for the presence of PDE5 inhibitors. The resulting signals were characterised by UV, LC-MS in ESI-negative mode, and NMR spectroscopy using 1D and 2D experiments. Several substances were identified, bearing the basic chemical structure of sildenafil, but were not supposed to exhibit PDE5 inhibition. These compounds may be process-related impurities or by-products of different reaction steps in the synthesis of PDE5 analogues. As they were fo...


Simultaneous determination of multi-mycotoxins in palm kernel cake (PKC) using liquid chromatography tandem mass spectrometry (LC-MS/MS).

Palm kernel cake (PKC) is a useful source of protein and energy for livestock. Recently PKC has been used as an ingredient in poultry feed. Mycotoxin contamination of PKC due to inappropriate handling during production and storage has increased public concern for economic losses and health risks for poultry and humans. This concern has accentuated the need for the evaluation of mycotoxins in PKC. Furthermore, a method for quantifying mycotoxins in PKC has so far not been established. The aims of this study ...

Sunday 31st December 1121

Magnetic Three-dimensional Graphene Solid-phase Extraction Of Chlorophenols From Honey Samples.

In this work, a novel magnetic three-dimensional graphene nano-composite (3D-G@Fe3O4) with a high surface area was synthesised by a vacuum freeze-dried method. Due to its high surface area, specific three-dimensional nano-porous structure and excellent magnetic properties, it can be used as a magnetic solid-phase extraction adsorbent. Some chlorophenols in honey samples were enriched by this nanocomposite prior to their determination by HPLC with ultraviolet detection. Factors that affect the extraction eff...

Saturday 9th July 1120

Arsenic: bioaccessibility from seaweed and rice, dietary exposure calculations and risk assessment.

Arsenic is a metalloid that occurs in food and the environment in different chemical forms. Inorganic arsenic is classified as a class I carcinogen. The inorganic arsenic intake from food and drinking water varies depending on the geographic arsenic background. Non-dietary exposure to arsenic is likely to be of minor importance for the general population within the European Union. In Europe, arsenic in drinking water is on average low, but food products (e.g. rice and seaweed) are imported from all over the...

Tuesday 4th August 1113

Comparison of plasma and tissue disposition of enrofloxacin in rainbow trout (Oncorhynhus myccis) and common carp (Cyprinus carpio) after single oral administration.

The aim of the study was to investigate the serum and tissue disposition of enrofloxacin and its active metabolite ciprofloxacin in rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus caprio) after single oral administration at a dose of 10 mg/kg. Concentrations of enrofloxacin in the serum of rainbow trout showed high variability with two peaks at the 3(rd) and 24th hour after administration. The highest concentrations were found in the liver. The curves of liver levels showed similar changes to ...

Monday 4th May 1113

Determination of the persistence of dimetridazole, metronidazole and ronidazole residues in black tiger shrimp (Penaeus monodon) tissue and stability during cooking.

The depletion of three banned nitroimidazole drugs (dimetridazole (DMZ), metronidazole (MNZ) and ronidazole (RNZ)) was investigated in black tiger shrimp (Penaeus monodon) following in-water medication. The highest concentrations of residues were measured immediately after the 24 h immersion (day 0). At this time, MNZ and MNZ-OH residues were measured in shrimp tissue samples at concentrations ranging from 361-4189 and 0.28-6.6 μg kg(-1), respectively. DMZ and its metabolites HMMNI ranged in concentration ...

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