PubMed Journal Database | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment RSS

07:32 EDT 17th September 2014 | BioPortfolio

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Showing PubMed Articles 1–25 of 180 from Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment


Determination of pyrrolizidine alkaloids in tea, herbal drugs and honey.

Honey was previously considered to be one of the main food sources of human pyrrolizidine alkaloid (PA) exposure in Europe. However, comprehensive analyses of honey and tea sampled in the Berlin retail market revealed unexpected high PA amounts in teas. Our study comprised the analysis of 87 honey as well as 274 tea samples including black, green, rooibos, melissa, peppermint, chamomile, fennel, nettle and mixed herbal tea or fruit tea. Total PA concentrations in tea ranged from

Thursday 11th April 1066

A simple and reliable liquid chromatography-tandem mass spectrometry method for the determination of aflatoxin B1 in feed.

Abstract A chromatographic method is proposed for the analysis of aflatoxin B1 in cereal-based feed, particularly targeted to dairy animals. The method is based on a solid-liquid extraction followed by a Mycosep 226 clean up. Accuracy and precision were established at the LOQ (1 µg kg(-1)) with a spiked sample as well as with two other different naturally contaminated reference materials. The mean overall recovery (n = 18) was 100.8% with a confidence interval of 2.7% and a CV% of 5.5%. The performance...


Determination of chloramphenicol residues in commercial chicken eggs in the Federal Capital Territory, Abuja, Nigeria.

The use of antibiotics in poultry can result in residues in eggs. The joint FAO/WHO committee recommended banning the use of chloramphenicol (CAP) in food animals due to its public health hazards of aplastic anemia, leukemia, allergy, antibacterial-resistance and carcinogenicity. In this paper we determined the prevalence of CAP residues in chicken eggs and assessed the usage and awareness of its ban amongst poultry farmers in the Federal Capital Territory (FCT), Abuja, Nigeria. A cross-sectional survey of ...


Impact of wine manufacturing practice on the occurrence of fining agents with allergenic potential.

Proteinogenic wine fining agents are hidden allergens and could present a risk for consumers with allergies. Therefore the European Parliament adopted Directive 2003/89/EC amending Directive 2000/13/EC to declare ingredients, contaminations and processing aids that are known to trigger allergic reactions. The Amendment Regulation (EU) 1266/2010 excluded the labeling of wines which are processed with hen´s egg and products thereof until June 30th, 2012 to get more scientific findings. After July 1st 2012 wi...


Multi-commutated fluorometric optosensor for the determination of citrinin in rice and red yeast rice supplements.

Citrinin is a toxic secondary metabolite first isolated from Penicillium citrinum, although is also produced by other species of Penicillium and Aspergillus. It has highly toxic, mutagenic, teratogenic and carcinogenic properties and is often found in crops, vegetables and fruit. To our knowledge there is no specific legislation on maximum levels permitted for citrinin, so no official analytical method is currently available for its determination. Our laboratory developed a fluorometric flow-through optosen...


Simultaneous determination of 30 hormones illegally added to anti-ageing functional foods using UPLC-MS/MS coupled with SPE clean-up.

A novel analytical method employing solid-phase extraction (SPE) coupled with ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was developed for the simultaneous determination of 30 hormones in anti-ageing functional foods (capsules, powders and tablets). The analytes were extracted with acetic acid-acetonitrile (1-99 v/v), methanol and acetone, respectively. The extract was purified using a combined column, followed by analyte detection with electrospray ionisation in pos...

Tuesday 9th January 1060

Determination of halosulfuron-methyl residues and dissipation in wheat by QuEChERS and LC-MS/MS.

A sensitive and rapid analytical method based on QuEChERS (quick, easy, cheap, effective, rugged, and safe) sample preparation and LC-MS/MS detection was developed for the analysis of halosulfuron-methyl residues in wheat. The recoveries of halosulfuron-methyl in the wheat plant and in wheat grain ranged from 87-119% and 75-97%, respectively, with relative standard deviations (RSDs) of 3-9%. The limit of quantification (LOQ) was 0.005 mg kg(-1) for wheat plant and 0.001 mg kg(-1) for wheat grain. The half-...


Monitoring of 35 illegally added steroid compounds in foods and dietary supplements.

Abstract The adulteration of foods and dietary supplements with steroids has been well attested and has the potential to be dangerous owing to various possible side effects. Therefore, detecting the presence of steroids in various health food products has become increasingly important. The purpose of this study was to monitor illegally adulterated health food products by applying multiple reaction monitoring (MRM) techniques to tandem liquid chromatography-mass spectrometry (LC-MS/MS). Various food and supp...


Development of a novel controlled-release nanocomposite based on poly(lactic acid) to increase the oxidative stability of soybean oil.

A poly(lactic acid) (PLA)-based nanocomposite active packaging was developed for the controlled release of tert-butylhydroquinone (TBHQ) antioxidant. The PLA-based active films were loaded with only TBHQ (3% wt) or a mixture of modified cellulose nanofibre (MCNF) (8% wt) and TBHQ (3% wt) to obtain active and nanocomposite active films, respectively. Release studies indicated that the release rate of TBHQ in 95% ethanol simulant was significantly decreased by the addition of MCNF. Moreover, the presence of M...


Energy drink consumption and impact on caffeine risk.

The impact of caffeine from energy drinks occurs against a background exposure from naturally occurring caffeine (coffee, tea, cocoa and foods containing these ingredients) and caffeinated beverages (kola type soft drinks). Background caffeine exposure, excluding energy drinks, was assessed for six New Zealand population groups aged 15 years and over (n = 4503) by combining concentration data for 53 caffeine containing foods with consumption information from the 2008/09 New Zealand Adult Nutrition Survey...

Sunday 5th October 1050

Probiotic lactic acid bacteria detoxify N-nitrosodimethylamine.

Humans can be exposed to N-nitroso compounds (NOCs) due to many environmental sources, as well as due to endogenous formation. The main nitrosamine which is found in food products and is also synthesized in vivo by the intestinal microbiota is N-nitrosodimethylamine. It can cause cancer of the stomach, kidney, and colon. The effect of four probiotic Lactobacillus strains on NDMA was studied under different culture conditions (24 h in MRS, 168 h in modified MRS N, and 168 h in phosphate buffer). HPLC and ...

Sunday 10th April 1047

Food contact substances and chemicals of concern: a comparison of inventories.

Food contact materials (FCMs) are intended to be in contact with food during production, handling or storage. They are one possible source of food contamination, because chemicals may migrate from the material into the food. More than 6000 FCM substances appear on regulatory or non-regulatory lists. Some of these substances have been linked to chronic diseases, whilst many others lack (sufficient) toxicological evaluation. The aim of this study was the identification of known FCM substances that are also co...

Wednesday 28th October 1034

Assessment of dietary phytoestrogen intake via plant-derived foods in China.

The potential influence of dietary phytoestrogen exposure on human health during different life phases including early childhood is a matter of scientific debate. In order to improve the risk-benefit assessment of exposure to dietary phytoestrogen, reliable and age-stratified exposure data are desirable. For contributing to the database on phytoestrogen exposure, in the present study plant-derived foods from the Chinese market were analysed by LC-MS/MS for their contents of phytoestrogens, including daidzei...


Estimation of intake of phenol compounds from virgin olive oil of a population from southern Spain.

The objective of the present study was to determine the mean polyphenol composition of different varieties of virgin olive oil habitually consumed in the region of southern Spain and to estimate the dietary exposure to olive oil polyphenols in that population. There were statistically significant differences in total polyphenols among varieties, with the Picual variety containing the largest amount with a mean value of 591.8 mg/kg. The main phenolic compounds found in the virgin olive oils under study were...


Validation of Explorer(®) 2.0 test coupled to e-Reader(®) for screening of antimicrobials in muscle from different animal species.

Explorer(®) 2.0 tube test is a microbial inhibition test for screening of antimicrobial residues in food samples. The new e-Reader(®) device coupled to Explorer(®) 2.0 test operates by incubation at a selected temperature, determination of the end-point of the assay and interpretation to generate results. This system was validated for muscle samples according to the European /657/EC. Sensitivity towards 25 substances from several groups of antimicrobials was investigated in a first step. Detection capabi...


Multi-class pesticide residue determination in dietary supplements from grape seed extracts by ultra-high performance liquid chromatography coupled to triple quadrupole mass spectrometry.

A new method has been developed and validated for the determination of multi-class pesticide residues in nutraceutical products obtained from grape seed extracts. The E extraction procedure was based on QuEChERS (quick, easy, cheap, effective, rugged and safe) methodology using ethyl acetate as solvent and dispersive solid phase extraction (dSPE) clean-up stage with C18 included to minimise matrix effects. Pesticides determination was achieved using ultra-high performance liquid chromatography coupled to tr...


A harmonised approach for identifying core foods for total diet studies.

Total diet studies (TDS) are used to gather information on chemical substances in food, thereby facilitating risk assessments and health monitoring. Candidate foods for inclusion in a TDS should represent a large part of a typical diet to accurately estimate exposure of a population and/or specific population groups. There are currently no harmonised guidelines for the selection of foods in a TDS, and so the aim of this study was to explore the possibility of generating a harmonised approach to be used acro...


Identifying core foods for total diet studies: a comparison of four different approaches.

Total diet studies (TDS) are recognised as a cost-effective approach in estimating dietary exposure to chemicals in food. It has been advised that candidate foods for inclusion in TDS analysis should represent a large part of the typical diet to accurately estimate exposure of a population group. To date, a variety of approaches have been used to determine which foods should be included in a core TDS food list, with no agreed method. Therefore, the aim of this study was to compare four of these approaches b...

Thursday 1st December 1013

Trans fatty acid content in Malaysian supermarket foods: a field to laboratory approach in assessing food risk.

The extent of industrial trans fatty acids (TFA) in the food supply is unknown in Malaysia whilst TFA disclosure on food labels is not mandatory by Malaysian food standards. Supermarket foods such as dairy products, fats and oils, meat products, snack foods, soups and confectionery are commonly cited to be major contributors of TFA in the diet. A consumer survey (n = 622) was used to develop a food listing of these "high risk" foods. TFA content of "high risk" foods were analyzed by gas chromatography. Fo...


Risk Control and Food Safety: Proceedings of the 11th UJNR International Symposium on Toxic Microorganisms, March 4-9, 2012, Tokyo, Japan.


Comparison of four different methods for the determination of sulfites in foods marketed in South Korea.

Sulfites in foods were analysed using four methods: optimised Monier-Williams (official method), modified Rankine, HPLC and ion-exchange chromatography (IEC). The modified Rankine and HPLC methods were performed according to the previously reported methods but with some modifications. The IEC method was carried out through a combination of a modified Rankine apparatus and an anion-exchange column for the first time. In false-positive response tests, false-positive results with acetic acid and propionic acid...


Sesamin and sesamolin as unexpected contaminants in various cold-pressed plant oils: NP-HPLC/FLD/DAD and RP-UPLC-ESI/MS(n) study.

Thirteen cold-pressed oils (Japanese quince seed, black caraway, flaxseed, rapeseed, hemp, peanut, sunflower, pumpkin, hazelnut, poppy, walnut, almond, and sesame oil) manufactured by the same company, in a two-year period (2011-2012) were assessed for lipophilic compounds. The presence of sesamin and sesamolin, two characteristic lignans of sesame oil, were detected in all tested plant oils. Both lignans were identified by NP-HPLC/FLD/DAD and confirmed by a RP-UPLC-ESI/MS(n) method. The lowest amount of se...


Determination of polycyclic aromatic hydrocarbons in Italian milk by HPLC with fluorescence detection.

The presence of polycyclic aromatic hydrocarbons (PAHs) in Italian commercial milk samples is reported. The study was carried out on lactating (cow and goat) and plant (rice, soya, oat) milk. The quantitative determination involved liquid-liquid extraction of PAHs, a pre-concentration and determination by HPLC using a fluorescence detector. The recovery of analytes was in the range of 70-115%. The precision of the method was found to be between 6% and 24%. The detection limit ranged from 0.66 to 33.3 µg/L...


Identification of novel metabolites from Aspergillus flavus by high resolution and multiple stage mass spectrometry.

The filamentous fungus Aspergillus flavus is one of the most important species in the Aspergillus genus and is distributed worldwide as a prevalent aflatoxin-producing food and feed contaminant. A. flavus contains more than 55 gene clusters that are predicted to encode proteins involved in secondary metabolite production. One of these, cluster 27, contains a polyketide synthase (pks27) gene that encodes a protein that is highly homologous to the aflatoxin cluster PKS. Comparative metabolomics, using ultra-h...


Development of an active wheat gluten film with L. curvatus CRL705 bacteriocins and a study of its antimicrobial performance during aging.

Antimicrobial wheat gluten film was obtained at pilot scale by Lactobacillus curvatus CRL705 bacteriocins inclusion in the film forming solution. Bacteriocins minimum inhibitory concentration for the film activation was 2133 AU cm(-3) (lactocin AL705) and 267 AU cm(-3) (lactocin 705). Mechanical and barrier properties as well as film aging kinectics were not significantly affected by bacteriocins addition. The antimicrobial film performance during aging was assessed. Film activity against Listeria innocua 7...

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