PubMed Journal Database | Journal of the American College of Cardiology

Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention for Non-ST-Segment Elevation Myocardial Infarction: Results of the SELECT-ACS Trial.

The study aimed to evaluate inclacumab for the reduction of myocardial damage during a percutaneous coronary intervention (PCI) in patients with non-ST-segment elevation myocardial infarction.

Targeting p-selectin during coronary interventions: the elusive link between inflammation and platelets to prevent myocardial damage.

Evaluation of Ranolazine in Patients With Type 2 Diabetes Mellitus and Chronic Stable Angina: Results From the TERISA Randomized Clinical Trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina).

This study sought to examine the efficacy of ranolazine versus placebo on weekly angina frequency and sublingual nitroglycerin use in subjects with type 2 diabetes mellitus, coronary artery disease (CAD), and chronic stable angina who remain symptomatic despite treatment with up to 2 antianginal agents.

Diabetes and coronary disease: a need for new therapies for an expanding disease burden.

Patterns of use and comparative effectiveness of bleeding avoidance strategies in men and women following percutaneous coronary interventions: an observational study from the national cardiovascular data registry.

This study sought to compared the use and effectiveness of bleeding avoidance strategies (BAS) by sex.

Predictive value of 6-min walk test distance versus cardiopulmonary exercise testing in systolic heart failure: same value for different approaches?

Reply.

Prognostic interplay of coronary artery calcification and underlying vascular dysfunction in patients with suspected coronary artery disease.

This study sought to evaluate the interrelation of atherosclerotic burden, as assessed by coronary artery calcium (CAC) score and coronary vascular function, as assessed by quantitative estimates of coronary flow reserve (CFR), with respect to prediction of clinical outcomes.

Genomics in cardiovascular disease.

A paradigm shift toward biology occurred in the 1990s and was subsequently catalyzed by the sequencing of the human genome in 2000. The cost of deoxyribonucleic acid (DNA) sequencing has gone from millions to thousands of dollars with sequencing of one's entire genome costing only $1,000. Rapid DNA sequencing is being embraced for single gene disorders, particularly for sporadic cases and those from small families. Transmission of lethal genes such as associated with Huntington's disease can, through in vit...

Renal impairment and ischemic stroke risk assessment in patients with atrial fibrillation: the loire valley atrial fibrillation project.

This study sought to determine the risk of ischemic stroke (IS)/thromboembolism (TE) associated with renal impairment and its incremental predictive value over established risk stratification scores (congestive heart failure, hypertension, age ≥75 years, diabetes, previous stroke [CHADS2] and congestive heart failure, hypertension, age ≥75 years, diabetes, previous stroke, vascular disease, age 65 to 74 years, sex category (female) [CHA2DS2-VASc]) in patients with atrial fibrillation (AF).

Unilateral rib notching in a tetralogy of fallot.

Channeling post-infarction ventricular tachycardia ablation: "electroanatomy" versus electrophysiology.

Doubly obstructive hypertrophic cardiomyopathy.

Triple antithrombotic therapy with prasugrel in the stented patient: concern for more bleeding.

Relationship between voltage map "channels" and the location of critical isthmus sites in patients with post-infarction cardiomyopathy and ventricular tachycardia.

The goal of this study was to determine the relationship of the ventricular tachycardia (VT) isthmus to channels of preserved voltage on an electroanatomic voltage map in postinfarction cardiomyopathy.

Triple therapy with aspirin, prasugrel, and vitamin k antagonists in patients with drug-eluting stent implantation and an indication for oral anticoagulation.

This study sought to evaluate whether prasugrel may serve as an alternative to clopidogrel in patients with triple therapy.

Hypothermia: Is it Good for the Brain and Not for the Arteries?

The incidence and clinical outcome of constrictive physiology after coronary artery bypass graft surgery.

The nanny state and "coercive paternalism".

Endovascular repair of ascending aortic dissection: a novel treatment option for patients judged unfit for direct surgical repair.

This paper sought to report the outcomes of patients who are considered unfit for urgent surgical repair of ascending aortic dissections (AADs) who were treated using a novel endovascular repair strategy.

Statin treatment and diabetes.

Inducible myocardial ischemia and outcomes in patients with coronary artery disease and left ventricular dysfunction.

The study objectives were to test the hypotheses that ischemia during stress testing has prognostic value and identifies those patients with coronary artery disease (CAD) with left ventricular (LV) dysfunction who derive the greatest benefit from coronary artery bypass grafting (CABG) compared with medical therapy.

How to balance cardiometabolic benefits and risks of statins.

Standardized cardiovascular data for clinical research, registries, and patient care: a report from the data standards workgroup of the national cardiovascular research infrastructure project.

Relatively little attention has been focused on standardization of data exchange in clinical research studies and patient care activities. Both are usually managed locally using separate and generally incompatible data systems at individual hospitals or clinics. In the past decade there have been nascent efforts to create data standards for clinical research and patient care data, and to some extent these are helpful in providing a degree of uniformity. Nonetheless, these data standards generally have not b...

Cardiac troponin I levels measured with a high-sensitive assay increase over time and are strong predictors of mortality in an elderly population.

This study sought to assess changes in troponin levels, underlying conditions, and the prognostic implications in elderly subjects from the community.