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PubMed Journal Database | Nano letters RSS

09:51 EDT 24th August 2016 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 1–25 of 3,000+ from Nano letters

Biomacromolecular stereostructure mediates mode hybridization in chiral plasmonic nanostructures.

The refractive index sensitivity of plasmonic fields has been exploited for over 20 years in analytical technologies. While this sensitivity can be used to achieve attomole detection levels, they are in essence binary measurements which sense the presence / absence of a pre-determined analyte. Using plasmonic fields, not to sense effective refractive indices, but to provide more "granular" information about the structural characteristics of a medium, provides a more information rich output, which affords op...

Role of 4-tert-Butylpyridine as a Hole Transport Layer Morphological Controller in Perovskite Solar Cells.

Hybrid organic-inorganic materials for high efficiency, low cost photovoltaic devices have seen rapid progress since the introduction of lead based perovskites and solid-state hole transport layers. Although majority of the materials used for perovskite solar cells (PSC) are introduced from dye-sensitized solar cells (DSSCs), the presence of a perovskite capping layer as opposed to a single dye molecule (in DSSCs) changes the interactions between the various layers in perovskite solar cells. 4-tert-butylpyr...

A New Approach for High-Voltage Electrical Double-Layer Capacitors Using Vertical Graphene Nanowalls with and without Nitrogen Doping.

Integrating various devices to achieve high-performance energy storage systems to satisfy various demands in modern societies become more and more important. Electrical double-layer capacitors (EDLCs), one kind of the electrochemical capacitors, generally provide the merits of high charge-discharge rates, extremely long cycle life, and high efficiency in electricity capture/storage, leading to a desirable device of electricity management from portable electronics to hybrid vehicles or even smart grid applic...

Large-scale Spinning of Silver Nanofibers as Flexible and Reliable Conductors.

Conducting metal nanowires can be assembled into thin films for flexible electronics and optoelectronics applications including transparent electrodes, nanocircuits, and electronic skin, however, the junction resistances and low aspect ratios still limit its performance. Herein we reports high-quality silver nanofibers (AgNFs) synthesized by a gas-assistant solution spinning method. Compared with traditional Ag nanowires which usually have lengths below 100 µm, AgNFs are infinitely long, and can be easily ...

Magnetic Drug Targeting: Preclinical in Vivo Studies, Mathematical Modeling, and Extrapolation to Humans.

A sound theoretical rationale for the design of a magnetic nanocarrier capable of magnetic capture in vivo after intravenous administration could help elucidate the parameters necessary for in vivo magnetic tumor targeting. In this work, we utilized our long-circulating polymeric magnetic nanocarriers, encapsulating increasing amounts of superparamagnetic iron oxide nanoparticles (SPIONs) in a biocompatible oil carrier, to study the effects of SPION loading and of applied magnetic field strength on magnetic...

Tuning the outward to inward swelling in lithiated silicon nanotubes via surface oxide coating.

Electrochemically-induced mechanical degradation hinders the application of Si anodes in advanced lithium-ion batteries. Hollow structures and surface coatings have been often used to mitigate the degradation of Si-based anodes. However, the structural change and degradation mechanism during lithiation/delithiation of hollow Si structures with coatings remain unclear. Here, we combine in situ TEM experiment and chemomechanical modeling to study the electrochemically-induced swelling of amorphous-Si (a-Si) n...

Cysteine-Cystine Photoregeneration for Oxygenic Photosynthesis of Acetic Acid from CO2 by a Tandem Inorganic-Biological Hybrid System.

Tandem "Z-scheme" approaches to solar-to-chemical production afford the ability to independently develop and optimize reductive photocatalysts for CO2 reduction to multicarbon compounds and oxidative photocatalysts for O2 evolution. To connect the two redox processes, molecular redox shuttles, reminiscent of biological electron transfer, offer an additional level of facile chemical tunability that eliminates the need for solid-state semiconductor junction engineering. In this work, we report a tandem inorga...

Creation of Controllable High-Density Defects in Silver Nanowires for Enhanced Catalytic Property.

Structural defects have been proven to determine many of the materials' properties. Here, we demonstrate a unique approach to the creation of Ag nanowires with high-density defects through controllable nanoparticle coalescence in one-dimensional pores of mesoporous silica. The density of defects can be easily adjusted by tuning the annealing temperature during synthetic process. The high-density defects promote the adsorption and activation of more reactants on the surface of Ag nanowires during catalytic r...

Self-Aligned Multi-Channel Graphene Nanoribbon Transistor Arrays Fabricated at Wafer Scale.

We present a novel method for fabricating large-area field effect transistors (FETs) based on densely packed multi-channel graphene nanoribbon (GNR) arrays using advanced direct self-assembly (DSA) nanolithography. The design of our strategy focused on efficient integration of the FET channel and fab-compatible processes such as thermal annealing and chemical vapor deposition. We achieved linearly stacked DSA nanopattern arrays with sub-10 nm half pitch critical dimension (CD) by controlling the thickness o...

Twisted bilayer graphene: Moiré with a twist.

A multiscale model is developed to predict the equilibrium structure of twisted bilayer graphene (tBLG). Two distinct, modified Moiré structures are observed. The breathing mode, stable at large twist angle, has small amplitude (opposite sign) buckling of the two layers. The bending mode is characterized by large amplitude (same sign) buckling of the layers. The latter gives rise to a distorted Moiré pattern consisting of a twisted dislocation structure. The relaxation of the Moiré structure reduces the ...

Tunneling Electron Induced Light Emission from Single Gold Nanoclusters.

The coupling of tunneling electrons with the tip-nanocluster-substrate junction plasmon was investigated by monitoring light emission in a scanning tunneling microscope (STM). Gold atoms were evaporated onto the ~5 Å thick Al2O3 thin film grown on the NiAl (110) surface where they formed nanoclusters 3 - 7 nm wide. Scanning tunneling spectroscopy (STS) of these nanoclusters revealed quantum-confined electronic states. Spatially resolved photon imaging showed localized emission hot spots. Size dependent stu...

Tracking optical welding through groove modes in plasmonic nano-cavities.

We report the light-induced formation of conductive links across nanometre-wide insulating gaps. These are realised by incorporating spacers of molecules or 2D monolayers inside a gold plasmonic nanoparticle-on-mirror (NPoM) geometry. Laser irradiation of individual NPoMs controllably reshapes and tunes the plasmonic system, in some cases forming conductive bridges between particle and substrate, which shorts the nanometre-wide plasmonic gaps geometrically and electronically. Dark-field spectroscopy monitor...

Ultra-low noise atomic scale structures for quantum circuitry in silicon.

The atomically precise doping of silicon with phosphorus (Si:P) using scanning tunneling microscopy (STM) promises ultimate miniaturization of field effect transistors. The one-dimensional (1D) Si:P nanowires are of particular interest, which retain exceptional conductivity down to the atomic scale, and predicted as interconnects for a scalable silicon-based quantum computer. Here we show that ultra-thin Si:P nanowires form one of the most stable electrical conductors, with the phenomenological Hooge parame...

Ultrathin epitaxial silicon solar cells with inverted nanopyramid arrays for efficient light trapping.

Ultrathin c-Si solar cells have the potential to drastically reduce costs by saving raw material, while maintaining good efficiencies thanks to the excellent quality of monocrystalline silicon. However, efficient light trapping strategies must be implemented to achieve high short-circuit currents. We report on the fabrication of both planar and patterned ultrathin c-Si solar cells on glass using low temperature (T

Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy.

Photodynamic therapy (PDT) has emerged as a promising clinical modality for cancer therapy due to its ability to initiate an antitumor immune response. However, PDT-mediated cancer immunotherapy is severely impaired by tumor cell immunosuppression of host T-cell antitumor activity through the programmed cell death 1 ligand (PD-L1) and programmed cell death receptor 1 (PD-1) (PD-L1/PD-1) immune checkpoint pathway. Here, we demonstrate that PDT-mediated cancer immunotherapy can be augmented by PD-L1 knockdown...

Gigahertz Acoustic Vibrations of Elastically Anisotropic Indium-Tin-Oxide Nanorod Arrays.

Active control of light is important for photonic integrated circuits, optical switches, and telecommunications. Coupling light with acoustic vibrations in nanoscale optical resonators offers optical modulation capabilities with high bandwidth and small footprint. Instead of using noble metals, here we introduce indium-tin-oxide nanorod arrays (ITO-NRAs) as the operating media and demonstrate optical modulation covering the visible spectral range (from 360 to 700 nm) with ∼20 GHz bandwidth through the exc...

Correction to van der Waals Heterostructures with High Accuracy Rotational Alignment.

Microfluidics-produced collagen fibers show extraordinary mechanical properties.

Collagens are widely used as biomaterials in drug-delivery and tissue engineering applications, due to their biodegradability, biocompatibility and hypoallergenicity. Besides gelatin-based materials, collagen microfibers are in the focus of biomedical research. Commonly, man-made fibers are produced by wet-spinning yielding fiber diameters higher than 8 µm. Here, assembly and continuous production of single collagen type I microfibers were established using a microfluidic chip. Microfluidics-produced micro...

Preferential Cancer Cell Self-Recognition and Tumor Self-Targeting by Coating Nanoparticles with Homotypic Cancer Cell Membranes.

The ultimate goal in cancer therapy and diagnosis is to achieve highly specific targeting to cancer cells. Coated with the source cancer cell membrane specifically derived from the homologous tumors, the nanoparticles are identified with the self-recognition internalization by the source cancer cell lines in vitro and the highly tumor-selective targeting "homing" to the homologous tumor in vivo even in the competition of another heterologous tumor. As the result, MNP@DOX@CCCM nanovehicle showed strong poten...

Graphene-based fluorescence-quenching-related Fermi-level elevation and electron-concentration surge.

Intermolecular p-orbital overlaps in unsaturated π-conjugated systems, such as graphene and fluorescent molecules with aromatic structure, serve as the electron-exchanged path. Using Raman-mapping measurements, we observe that the fluorescence intensity of fluorescein isothiocyanate (FITC) is quenched by graphene whereas it persists in graphene-absent substrates (SiO2). After identifying a mechanism related to photon-induced electron transfer (PET) that contributes to this fluorescence quenching phenomenon...

Rapid, In-situ Synthesis of High Capacity Battery Anodes Through High Temperature Radiation-based Thermal Shock.

High capacity battery electrodes require nanosized components to avoid pulverization associated with volume changes during the charge-discharge process. Additionally, these nanosized electrodes need an electronically conductive matrix to facilitate electron transport. Here, for the first time, we report a rapid thermal shock process using high temperature radiative heating to fabricate a conductive reduced graphene oxide (RGO) composite with silicon nanoparticles. Silicon (Si) particles on the order of a fe...

Resolving and Tuning Mechanical Anisotropy in Black Phosphorus via Nanomechanical Multimode Resonance Spectromicroscopy.

Black phosphorus (P) has emerged as a layered semiconductor with unique crystal structure featuring corrugated atomic layers and strong in-plane anisotropy in its physical properties. Here we demonstrate that the crystal orientation and mechanical anisotropy in free-standing black P thin layers can be precisely determined by spatially resolved multimode nanomechanical resonances. This offers a new means for resolving important crystal orientation and anisotropy in black P device platforms in situ, beyond co...

Bio-mimetic ant-nest electrode structures for high sulfur ratio lithium-sulfur batteries.

The lithium-sulfur (Li-S) rechargeable battery has the benefit of high gravimetric energy density and low cost. Significant research currently focuses on increasing the sulfur loading and sulfur/inactive-materials ratio, to improve life and capacity. Inspired by nature's ant-nest structure, this research results in a novel Li-S electrode that is designed to meet both goals. With only three simple manufacturing-friendly steps, which include slurry ball-milling, doctor-blade-based laminate casting, and use of...

Detailed Observation of Multiphoton Emission Enhancement from a Single Colloidal Quantum Dot Using a Silver-Coated AFM Tip.

The enhancement of multiphoton emission from a single colloidal nanocrystal quantum dot (NQD) interacting with a plasmonic nanostructure was investigated using a silver-coated atomic force microscopy tip (AgTip) as the plasmonic nanostructure. Using the AgTip, which exhibited a well-defined localized surface plasmon (LSP) resonance band, we controlled the spectral overlap and the distance between the single NQD and the AgTip. The emission behavior of the single NQD when approaching the AgTip at the nanomete...

Resonantly enhanced second-harmonic generation using III-V semiconductor all-dielectric metasurfaces.

Nonlinear optical phenomena in nanostructured materials have been challenging our perceptions of nonlinear optical processes that have been explored since the invention of lasers. For example, the ability to control optical field confinement, enhancement, and scattering almost independently, allows nonlinear frequency conversion efficiencies to be enhanced by many orders of magnitude compared to bulk materials. Also, the subwavelength length scales render phase matching issues irrelevant. Compared with plas...


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