PubMed Journals Articles About "Developmental Biology Brainy Background" RSS

08:04 EDT 21st August 2017 | BioPortfolio

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Showing "Developmental biology brainy background" PubMed Articles 1–25 of 12,000+

Lessons from Interspecies Mammalian Chimeras.

As chimeras transform from beasts of Greek mythology into tools of contemporary bioscience, secrets of developmental biology and evolutionary divergence are being revealed. Recent advances in stem cell biology and interspecies chimerism have generated new models with extensive basic and translational applications, including generation of transplantable, patient-specific organs. Expected final online publication date for the Annual Review of Cell and Developmental Biology Volume 33 is October 6, 2017. Please...

Illuminating developmental biology through photochemistry.

Developmental biology has been continually shaped by technological advances, evolving from a descriptive science into one immersed in molecular and cellular mechanisms. Most recently, genome sequencing and 'omics' profiling have provided developmental biologists with a wealth of genetic and biochemical information; however, fully translating this knowledge into functional understanding will require new experimental capabilities. Photoactivatable probes have emerged as particularly valuable tools for investi...

Biology of aging: new models, new methods.

The honeybee as a model insect for developmental genetics.

Honeybees are an important component of modern agricultural systems, and a fascinating and scientifically engrossing insect. Honeybees are not commonly used as model systems for understanding development in insects despite their importance in agriculture. Honeybee embryogenesis, while being superficially similar to Drosophila, is molecularly very different, especially in axis formation and sex determination. In later development, much of honeybee biology is modified by caste development, an as yet poorly un...

The evo-devo of plant speciation.

Speciation research bridges the realms of macro- and microevolution. Evolutionary developmental biology (evo-devo) has classically dealt with macroevolutionary questions through a comparative approach to distantly related organisms, but the field later broadened in focus to address recent speciation and microevolution. Here we review available evidence of the power of evo-devo approaches to understand speciation in plants at multiple scales. At a macroevolutionary scale, evidence is accumulating for evoluti...

How Single-Cell Genomics Is Changing Evolutionary and Developmental Biology.

The recent flood of single-cell data not only boosts our knowledge of cells and cell types, but also provides new insight into development and evolution from a cellular perspective. For example, assaying the genomes of multiple cells during development reveals developmental lineage trees-the kinship lineage-whereas cellular transcriptomes inform us about the regulatory state of cells and their gradual restriction in potency-the Waddington lineage. Beyond that, the comparison of single-cell data across speci...

John Saunders' ZPA, Sonic hedgehog and digit identity - how does it really all work?

Among John Saunders' many seminal contributions to developmental biology, his discovery of the limb 'zone of polarizing activity' (ZPA) is arguably one of the most memorable and ground-breaking. This discovery introduced the limb as a premier model for understanding developmental patterning and promoted the concept of patterning by a morphogen gradient. In the 50 years since the discovery of the ZPA, Sonic hedgehog (Shh) has been identified as the ZPA factor and the basic components of the signaling pathway...

An Intervention Supporting the Mental Health of Children with a Refugee Background.

This contribution proposes an intervention methodology that provides improved access to and effectiveness of mental health care facilities in Brussels, Belgium, for children and their families with a refugee and migration background. Migration is a complex process that involves several potential risk factors, and referral to mental health facilities is often ineffective. Consequently, optimal developmental opportunities for refugee children are hampered. The intervention is underpinned by a broad-based cont...

Symmetry breaking in development and stochastic gene expression.

The prevailing emphasis in developmental biology since the expansion of the molecular biology age has been that developmental decisions are instructive. A cell differentiates to become a specific cell type because it receives a signal, whereas its neighbor that does not receive the signal adopts a different fate. This emphasis has been generally accepted, largely because of the success of this view in tractable invertebrate model organisms, and the widespread similarities in molecular regulation to the deve...

A Geometric Model of Stripe Refinement.

Organizing data about patterning and morphogenesis into a coherent framework remains a challenge in developmental biology. Reporting in Science, Corson et al. (2017) apply innovative analysis to an old problem of bristle patterns in Drosophila, reducing the nonlinear interactions among tens of cells to a succinct model with quantitative predictions.


Keynote Symposium.

Plenary Symposia.

Plant Posters.

Regulation of development by SOX proteins.

Plant Symposia and Workshops.

Plant Contributed Papers.

Education Symposia and Workshops.

Education Silent Abstracts.

Developmental biology: Formation of hybrid myocardial zone.

Robo-Enabled Tumor Cell Extrusion.

How aberrant cells are removed from a tissue to prevent tumor formation is a key question in cancer biology. Reporting in this issue of Developmental Cell, Vaughen and Igaki (2016) show that a pathway with an important role in neural guidance also directs extrusion of tumor cells from epithelial tissues.

Poly (ADP-ribose) polymerase in growth, death, multicellularity.

Charting developmental dissolution of pluripotency.

The formation of tissues and organs during metazoan development begs fundamental questions of cellular plasticity: How can the very same genome program diverse cell types? How do cell identity programs unfold during development in space and time? How can defects in these mechanisms cause disease and also provide opportunities for therapeutic intervention? And ultimately, can developmental programs be exploited for bioengineering tissues and organs? Understanding principle designs of cellular identity and de...

Sensory Biology: How Female Treefrogs Pick Mates at a Noisy Party.

A recent study has found that, despite strong acoustic masking from background noise, female treefrogs are able to select among individual males advertising for mates by taking advantage of small, periodic decreases in the overall noise structure.

Cellular aspects of gonadal atrophy in Drosophila P-M hybrid dysgenesis.

Gonadal atrophy is the most typical and dramatic manifestation of intraspecific hybrid dysgenesis syndrome leading to sterility in Drosophila melanogaster dysgenic progeny. The P-M system of hybrid dysgenesis is primarily associated with germ cell degeneration during the early stages of Drosophila embryonic development at elevated temperatures. In the present study, we have defined the phase of germ cell death as beginning at the end of embryogenesis immediately following gonad formation. However, the tempe...

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