PubMed Journals Articles About "Developmental Biology Brainy Background" RSS

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Showing "Developmental biology brainy background" PubMed Articles 1–25 of 16,000+

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Reviewer acknowledgement 2013.

The editors of BMC Developmental Biology would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).

Modelling from the experimental developmental biologists viewpoint.

In this review we consider Reaction-Diffusion as the archetype of a model in developmental biology. We consider its history in relation to experimental work since it was first proposed in 1952 by Turing and revived in the 1970s by Meinhardt. We then discuss the most recent examples of experiments that address this model, including the challenges that remain in capturing the physico-chemical manifestation of the model mechanism in a real developmental system. Finally we discuss the model's current status and...

Unravelling the developmental regulatory networks in early animals.

Scanning electron microscopy analysis of floral development.

Scanning Electron Microscopy (SEM) allows the morphological characterization of the surface features of floral and inflorescence structures in a manner that retains the topography or three-dimensional appearance of the structure. Even at relatively low magnification levels it is possible to characterize early developmental stages. Using medium to high power magnification at later stages of development, cell surface morphology can be visualized allowing the identification of specific epidermal cell types. Th...

Summarizing craniofacial genetics and developmental biology (SCGDB).

This overview article highlights active areas of research in craniofacial genetics and developmental biology as reflected in presentations given at the 34th annual meeting of the Society of Craniofacial Genetics and Developmental Biology (SCGDB) in Montreal, Quebec on October 11, 2011. This 1-day meeting provided a stimulating occasion that demonstrated the present status of research in craniofacial genetics and developmental biology and where the field is heading. To accompany the abstracts published in th...

The chick embryo as an expanding experimental model for cancer and cardiovascular research.

A long and productive history in biomedical research defines the chick as a model for human biology. Fundamental discoveries, including the description of directional circulation propelled by the heart and the link between oncogenes and the formation of cancer, indicate its utility in cardiac biology and cancer. Despite the more recent arrival of several vertebrate and invertebrate animal models during the last century, the chick embryo remains a commonly used model for vertebrate biology and provides a tra...

In-silico models of stem cell and developmental systems.

Understanding how developmental systems evolve over time is a key question in stem cell and developmental biology research. However, due to hurdles of existing experimental techniques, our understanding of these systems as a whole remains partial and coarse. In recent years, we have been constructing in-silico models that synthesize experimental knowledge using software engineering tools. Our approach integrates known isolated mechanisms with simplified assumptions where the knowledge is limited. This has p...

Retraction: “Joined at the hip? A paleoepidemiological study of developmental dysplasia of the hip and its relation to swaddling practices among indigenous peoples of North America” by Samantha H. Blatt.

Integrating Diverse Datasets Improves Developmental Enhancer Prediction.

Gene-regulatory enhancers have been identified using various approaches, including evolutionary conservation, regulatory protein binding, chromatin modifications, and DNA sequence motifs. To integrate these different approaches, we developed EnhancerFinder, a two-step method for distinguishing developmental enhancers from the genomic background and then predicting their tissue specificity. EnhancerFinder uses a multiple kernel learning approach to integrate DNA sequence motifs, evolutionary patterns, and di...

"Surprised by Joy"*: Four Decades of Contributions to Developmental Physiology.

Presented at the 40th Anniversary Celebration of the Center for Perinatal Biology of Loma Linda University School of Medicine, honoring Dr. Longo for his 40 years of extraordinary leadership and service, February 11, 2013.

Developmental biology: Tethered wings.

Preface.

Multicolor labeling in developmental gene regulatory network analysis.

The sea urchin embryo is an important model system for developmental gene regulatory network (GRN) analysis. This chapter describes the use of multicolor fluorescent in situ hybridization (FISH) as well as a combination of FISH and immunohistochemistry in sea urchin embryonic GRN studies. The methods presented here can be applied to a variety of experimental settings where accurate spatial resolution of multiple gene products is required for constructing a developmental GRN.

Endocytosis and Signaling during Development.

The development of multicellular organisms relies on an intricate choreography of intercellular communication events that pattern the embryo and coordinate the formation of tissues and organs. It is therefore not surprising that developmental biology, especially using genetic model organisms, has contributed significantly to the discovery and functional dissection of the associated signal-transduction cascades. At the same time, biophysical, biochemical, and cell biological approaches have provided us with...

Editorial: LANDMARKS IN DEVELOPMENTAL BIOLOGY AND EVOLUTION.

Corrigendum.

Available for a limited time only: regulating gene expression through mRNA turnover.

Study on Developmental- Behavioural Pediatrics Training Experiences of Pediatricians and Pediatric Trainees Working in Nepal.

Background There are growing concerns about developmental, behavioural, social and emotional wellbeing of children throughout the world. A huge gap exists between the instructions provided on medical disciplines and on areas of Developmental- Behavioural Pediatrics (DBP) during pediatric training in our region. Objective This study aims to evaluate the Developmental -Behavioural pediatrics (DBP) training experiences of pediatricians and pediatric trainees during their post graduate training in pediatrics. M...

Ectodysplasin research-Where to next?

Ectodysplasin (Eda) is the most studied tumor necrosis ligand in the field of developmental biology. In all vertebrates studied so far, inactivating germline mutations in Eda lead to the genetic disease called hypohidrotic ectodermal dysplasia (HED). In humans, HED is a life-threatening condition in particular in infants due to absent or severely reduced sweating leading to hyperthermia. HED is also characterized by sparse hair, and oligo- or anodontia. Research of the Eda pathway has not only increased our...

Reforming the kidney starting from a single-cell suspension.

Background: Chronic kidney disease affects 5-7% of people worldwide. The increasing number of patients and the shortage of transplantable organs create an imperative need to develop new methods for generating kidney tissue. Summary: Recent advances in our understanding of the developmental biology of the kidney, along with the establishment of novel methodologies in the field of regenerative medicine, have created significant potential for kidney regeneration. These advances incorporate both transplantation...

Cancer: A disease of highly efficient and creative genome management?

Retraction notice to "The human placenta is a hematopoietic organ during the embryonic and fetal periods of development" Dev. Biol. 327 (2009) 24–33.

Model species in evo-devo: a philosophical perspective.

A model is a representation of or an analogy for something else; in a biological context, the term often refers to organisms or species that serve as a widely used platform for experimental research. In developmental biology, an extraordinarily detailed understanding of fundamental genes and mechanisms has been built around a few core models including Drosophila, mouse, Caenorhabditis elegans, Arabidopsis, and zebrafish. The use of model species entails a series of epistemological issues and commitments reg...

Promoting replication and repair in the right place at the right time (comment on DOI 10.1002/bies.201300161).

Spore formation in Bacillus subtilis.

Although prokaryotes ordinarily undergo binary fission to produce two identical daughter cells, some are able to undergo alternative developmental pathways that produce daughter cells of distinct cell morphology and fate. One such example is a developmental programme called sporulation in the bacterium Bacillus subtilis, which occurs under conditions of environmental stress. Sporulation has long been used as a model system to help elucidate basic processes of developmental biology including transcription re...


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