PubMed Journals Articles About "Developmental Biology Brainy Background" RSS

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Showing "Developmental biology brainy background" PubMed Articles 1–25 of 12,000+

The Renaissance of Developmental Biology.

Since its heyday in the 1980s and 90s, the field of developmental biology has gone into decline; in part because it has been eclipsed by the rise of genomics and stem cell biology, and in part because it has seemed less pertinent in an era with so much focus on translational impact. In this essay, I argue that recent progress in genome-wide analyses and stem cell research, coupled with technological advances in imaging and genome editing, have created the conditions for the renaissance of a new wave of deve...

Plant developmental transitions: the role of microRNAs and sugars.

What determines the rate at which a multicellular organism ages is a mystery in biology. In plants the changes in morphological and physiological traits serve as markers for the developmental transitions. Mutant characterizations and genetic analyses in Arabidopsis thaliana delineate an evolutionarily conserved, microRNA156 (miR156)-guided timing mechanism that temporally regulates many aspects of biological processes during development. Recent studies now reveal that sugar metabolites, the products of phot...

The childhood solid tumor network: A new resource for the developmental biology and oncology research Communities.

Significant advances have been made over the past 25 years in our understanding of the most common adult solid tumors such as breast, colon, lung and prostate cancer. Much less is known about childhood solid tumors because they are rare and because they originate in developing organs during fetal development, childhood and adolescence. It can be very difficult to study the cellular origins of pediatric solid tumors in developing organs characterized by rapid proliferative expansion, growth factor signaling,...

Decoding the jargon of bottom-up metabolic systems biology.

Bottom-up metabolic systems biology is of particular relevance to biochemists. The jargon of bottom-up metabolic systems biology however represents a major obstacle that needs to be overcome by a prospective practitioner in this emerging field. Herein, we diminish this early hurdle by providing a lexicon of the most important terms.

Arabidopsis casein kinase 2 α4 subunit regulates various developmental pathways in a functionally overlapping manner.

Casein kinase 2 (CK2) is an essential and well-conserved Ser/Thr kinase that regulates proteins in a posttranslational manner. CK2 has been shown to affect a large number of developmental processes across eukaryotes. It is a tetrameric protein composed of a dimer of alpha (catalytic) and beta (regulatory) subunit each. In our previous study we showed that three of the four CK2 α subunits in Arabidopsis act in a functionally redundant manner to regulate various developmental pathways. In this study we const...

Cell death in development: Signaling pathways and core mechanisms.

Programmed cell death eliminates unneeded and dangerous cells in a timely and effective manner during development. In this review, we examine the role cell death plays during development in worms, flies and mammals. We discuss signaling pathways that regulate developmental cell death, and describe how they communicate with the core cell death pathways. In most organisms the majority of developmental cell death is seen in the nervous system. Therefore we focus on what is known about the regulation of develop...



Developmental biology: Nanotubes in the niche.

Developmental biology: Stem cells for bone growth.

2015 BSDB Spring Meeting Report.

SIRT7 and hepatic lipid metabolism.

Glycoprotein maturation and quality control.

Blood-brain barrier in health and disease.

Characterisation of the Small RNAs in the Biomedically Important Green-Bottle Blowfly Lucilia sericata.

The green bottle fly maggot, Lucilia sericata, is a species with importance in medicine, agriculture and forensics. Improved understanding of this species' biology is of great potential benefit to many research communities. MicroRNAs (miRNA) are a short non-protein coding regulatory RNA, which directly regulate a host of protein coding genes at the translational level. They have been shown to have developmental and tissue specific distributions where they impact directly on gene regulation. In order to impr...

Do I have enough to write a paper? Where should I start and end?

The 2001 uses of GFP: A review of "Illuminating Disease"

When am I dead? Another case for some applied philosophy…., a customizable URL shortener for the NCBI My Bibliography.

Big questions and skepsis: Review of "In Search of Cell History.

New developmental data for Cynomya mortuorum (L., 1761) in Belgium (Diptera: Calliphoridae).

The calliphorid Cynomya mortuorum (L., 1761) is a forensically important species mainly found in the Palearctic region. Knowledge about its biology and ecology is scarce. Thermal constants as well as developmental time were studied at constant and variable regimes of 5 average temperatures: 14, 16, 18, 20 and 22°C, respectively. Total developmental time varied between 15.82±0.40 days at 22°C and 28.67±2.38 days at 14°C, for the constant regime, and between 16.05±0.67 days at 22°C and 32.79±1.77 days...

Peroxisomes: A small step from mitochondria but a giant leap for eukaryotes.

A universal model for the evolution of viviparity? (Comment on DOI 10.1002/bies.201400200).

The many faces of cell adhesion during Drosophila muscle development.

Muscle development involves a series of morphogenetic events including cell fusion, migration and epidermal attachment. At various points in this complex developmental program, regulation of muscle-muscle and muscle-epidermal adhesion is crucial. One of the best-characterised adhesion events is the formation of stable, integrin-based adhesions at the attachment sites formed between the ends of muscles and epidermal cells, but other adhesion mechanisms are involved in earlier stages. Here we review recent wo...

A critique of why looks can be deceptive in judging the health of well-fed corals (related to DOI 10.1002/bies.201400074).


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