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PubMed Journals Articles About "Late John Mendlein Joins Reinventing Biotech Lineup April" RSS

12:04 EDT 20th April 2014 | BioPortfolio

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Showing "Late John Mendlein Joins Reinventing Biotech Lineup April" PubMed Articles 1–25 of 2,700+


Reinventing adherent cell culture monitoring.

Biotech methods and advances.

Cover illustration: Our latest Biotech Methods & Advances special issue is edited by our Editors-in-Chief Prof. Alois Jungbauer and Prof. Sang Yup Lee. As always, the special issue is a collection of the latest breakthroughs in biotechnology. The cover is a graphical representation of some of the tools in biotechnology research. Image: © Bank-Bank -

Editorial: Latest methods and advances in biotechnology.

The latest "Biotech Methods and Advances" special issue of Biotechnology Journal continues the BTJ tradition of featuring the latest breakthroughs in biotechnology. The special issue is edited by our Editors-in-Chief, Prof. Sang Yup Lee and Prof. Alois Jungbauer and covers a wide array of topics in biotechnology, including the perennial favorite workhorses of the biotech industry, Chinese hamster ovary (CHO) cell and Escherichia coli.

What's fueling the biotech engine-2012 to 2013.

Biotech patents and science policy: the Spanish experience.

Prevalence and risk factors of late presentation for HIV diagnosis and care in a tertiary referral centre in Switzerland.

We sought to identify reasons for late human immunodeficiency virus (HIV) testing or late presentation for care.

Occupations that People with Late Effects of Polio Perceive Difficult to Perform.

The aims of this study were to describe which occupations that people with late effects of polio perceive difficult to perform, which occupational area the occupations were related to and their level of complexity. The aims were also to describe their own perception of the importance, performance and satisfaction with these occupations. Sixty-two participants (mean age 61 years) were assessed with the Canadian Occupational Performance Measure. A total of 431 occupations were reported (43% self-care, 32% p...

Intraperitoneal Tension-free Repair of a Small Midline Ventral Abdominal Wall Hernia: Randomized Study with a Mean Follow-up of 3 Years.

Funding received from Cousin Biotech, Wervicq Sud, France, and CR Bard Inc., Cranston, RI. The aim of this prospective randomized study was to determine the long-term recurrence and complication rates after small abdominal wall hernia repair with two different bilayer prostheses. Hernia repair using prosthetic mesh material has become the preferred method of repair, because the recurrence rates are much lower than with conventional repair techniques. The use of a hernia bilayer patch, composite expanded pol...

Stent-related defects in patients presenting with stent thrombosis: differences at optical coherence tomography between subacute and late/very late thrombosis in the Mechanism Of Stent Thrombosis (MOST) study.

Aims: Subacute, late, and very late stent thrombosis (ST) may occur after stent implantation, but they are characterised by different underlying pathophysiological mechanisms. We sought to appraise differences between subacute and late/very late ST at the thrombus site by optical coherence tomography (OCT). The Mechanism Of Stent Thrombosis (MOST) study was a prospective multicentre non-randomised registry which enrolled six subacute ST and six controls (subacute ST study), and 17 late/very late ST and 17 c...

Reinventing the case study for community health and primary care research.

Five-factor model personality domains in the prediction of Axis II personality disorders: An exploratory study in late adulthood women non-clinical sample.

Relationships between Axis II personality disorders (DSM-IV) and the five-factor model were explored in a non-clinical sample of late adulthood women. The sample consists of 90 women (M = 72.29 years of age, standard deviation = 7.10), who were administered with two measures, the NEO-FFI and the Personality Diagnostic Questionnaire-4+. Some personality disorders scales such as paranoid, schizotypal, borderline and dependent demonstrate a differentiated pattern of five-factor model domain predictor...

Atg5 regulates late endosome and lysosome biogenesis.

Autophagy is an evolutionarily conserved lysosome-based degradation process. Atg5 plays a very important role in autophagosome formation. Here we show that Atg5 is required for biogenesis of late endosomes and lysosomes in an autophagy-independent manner. In Atg5 (-/-) cells, but not in other essential autophagy genes defecting cells, recycling and retrieval of late endosomal components from hybrid organelles are impaired, causing persistent hybrid organelles and defective formation of late endosomes and ly...

Social support in late life mania: GERI-BD.

Using the database of the National Institute of Mental Health-sponsored acute treatment of late life mania study (GERI-BD), we assessed the role of social support in the presentation of late life bipolar mania.

Sir John Warcup Cornforth (1917-2013).

With the death of the remarkable organic chemist Sir John Warcup Cornforth, winner of the 1975 Nobel Prize in Chemistry, an era of biological chemistry has ended. His scientific achievements ranged across quite diverse areas, especially the elucidation of the stereochemistry of cholesterol biosynthesis.

Survivors of Childhood Cancer in South Australia Attending a Late Effects Clinic: A Descriptive Report of Psychological, Cognitive, and Academic Late Effects.

Abstract This study provides a description of psychological late effects among a heterogeneous cohort of pediatric cancer survivors (n = 70) attending the South Australian Late Effects Clinic. Survivors reported more problems on the Strengths and Difficulties Questionnaire and the Child Behavior Checklist compared to normative data but no differences in Sluggish Cognitive Tempo scores. 46% of the sample reported school difficulties and 12% of the sample aged over 15 reported smoking. Late effects clinics sh...

Unconventional Sequence Requirement for Viral Late Gene Core Promoters of Murine Gammaherpesvirus 68.

Infection with the human gammaherpesviruses, Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV), is associated with several cancers. During lytic replication of herpesviruses, viral genes are expressed in an ordered cascade. However, the mechanism by which late gene expression is regulated has not been well characterized in gammaherpesviruses. In this study, we have investigated the cis element that mediates late gene expression during de novo lytic infection of murine gammaherpesvi...

Injuries and Post-Traumatic Stress following Historic Tornados: Alabama, April 2011.

We analyzed tornado-related injuries seen at hospitals and risk factors for tornado injury, and screened for post-traumatic stress following a statewide tornado-emergency in Alabama in April 2011.

Xbox--a source of nickel exposure in children.

Macintosh laptop computers and iPhone5s were recently added to the list of potential nickel sources. The Xbox gaming controller also joins the list.

New FDA Draft Guidance on Immunogenicity.

A "Late Breaking" session was held on May 20 at the 2013 American Association of Pharmaceutical Scientists-National Biotech Conference (AAPS-NBC) to discuss the US Food and Drug Administration's (FDA) 2013 draft guidance on Immunogenicity Assessment for Therapeutic Protein Products. The session was initiated by a presentation from the FDA which highlighted several key aspects of the 2013 draft guidance pertaining to immunogenicity risk, the potential impact on patient safety and product efficacy, and risk m...

The Role of Late I Na in Development of Cardiac Arrhythmias.

Late I Na is an integral part of the sodium current, which persists long after the fast-inactivating component. The magnitude of the late I Na is relatively small in all species and in all types of cardiomyocytes as compared with the amplitude of the fast sodium current, but it contributes significantly to the shape and duration of the action potential. This late component had been shown to increase in several acquired or congenital conditions, including hypoxia, oxidative stress, and heart failure, or due...

Effectiveness of psychopharmacotherapy of late hypochondriac depression.

Hypochondriac depression is typical for elderly people and is difficult to treat. An aim of the study was to estimate the effect of hypochondriac symptoms on the effectiveness of psychopharmacotherapy of late depression. It has been shown that psychopharmacotherapy of late depression with hypochondriac symptoms is significantly less effective than that of depression without such symptoms. Some predictors of psychopharmacotherapy effectiveness were identified. Many prognostically significant factors were con...

Neuroimaging Findings in Late-Onset Schizophrenia and Bipolar Disorder.

In recent years, there has been an increasing interest in late-onset mental disorders. Among them, geriatric schizophrenia and bipolar disorder are significant health care risks and major causes of disability. We discussed whether late-onset schizophrenia (LOS) and late-onset bipolar (LOB) disorder can be a separate entity from early-onset schizophrenia (EOS) and early-onset bipolar (EOB) disorder in a subset of late-life schizophrenia or late-life bipolar disorder through neuroimaging studies. A literature...

Iron deficiency anemia in late-preterm infants.

Iron deficiency anemia is a common problem in newborn infants. The American Academy of Pediatrics recommends iron prophylaxis at 4 months of age for term infants. There is no specific recommendation for iron prophylaxis in late-preterm infants. We aimed to establish the optimum time for iron prophylaxis in late-preterm infants. Thirty-eight late-preterm (Group 1) and 38 term (Group 2) infants born on the same day were enrolled in the study. Hemoglobin, ferritin and reticulocyte values at birth, 2nd month an...

J&J partners with yale to share trial data.

Johnson & Johnson (J&J) joins GlaxoSmithKline, Pfizer, Roche, and other pharmaceutical companies in sharing its clinical trial data with researchers. J&J, however, is the only company to enlist an independent academic partner to review every request for data and decide who gets access.

Late Survival After Aortic Valve Replacement With the Perimount Versus the Mosaic Bioprosthesis.

The objective was to compare late survival after aortic valve replacement (AVR) with a Carpentier-Edwards Perimount (Edwards Lifesciences, Irvine, CA) versus a Mosaic bioprosthesis (Medtronic Inc, Minneapolis, MN). Secondary objectives were to compare early mortality, the rate of reoperation, and the effect of prosthesis-patient mismatch (PPM) on late survival.

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