PubMed Journals Articles About "Phillips" 
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Showing "Phillips" PubMed Articles 1–25 of 73
Standard reference materials for food analysis.
Throughout the development of breath analysis research, there has been interest in how the concentrations of trace compounds in exhaled breath are related to their concentrations in the ambient inhaled air. In considering this, Phillips introduced the concept of 'alveolar gradient' and judged that the measured exhaled concentrations of volatile organic compounds should be diminished by an amount equal to their concentrations in the inhaled ambient air. The objective of the work described in this paper was t...
Photothermal nanodrugs: potential of TNF-gold nanospheres for cancer theranostics.
Nanotechnology has been extensively explored for drug delivery. Here, we introduce the concept of a nanodrug based on synergy of photothermally-activated physical and biological effects in nanoparticle-drug conjugates. To prove this concept, we utilized tumor necrosis factor-alpha coated gold nanospheres (Au-TNF) heated by laser pulses. To enhance photothermal efficiency in near-infrared window of tissue transparency we explored slightly ellipsoidal nanoparticles, its clustering, and laser-induced nonlinear...
Characterisation of commercial LM-pectin in aqueous solution.
Fourteen commercial LM-pectin samples were investigated in this study. The degree of esterification (DE) varied from 9.6% to 42.0% and the degree of amidation (DA) from 0% to 25%. Chemical and structural characteristics were examined using atomic absorption (AA), dilute solution capillary viscometry, GPC-MALLS and dynamic light scattering. The intrinsic calcium was in the range of 47-1388ppm, the intrinsic viscosity varied from 2.9 to 4.9 (dL/g) and the weight average molecular weight (M(w)) from 113 to 290...
Improved Sugar Beet Pectin-Stabilized Emulsions through Complexation with Sodium Caseinate.
The study investigates the complexes formed between sodium caseinate (SC) and sugar beet pectin (SBP) and to harness them to stabilize SBP emulsions. We find that both hydrophobic and electrostatic interactions are involved in the complexation. In SC/SBP mixed solution, soluble SC/SBP complexes first form on acidification and then aggregate into insoluble complexes, which disassociate into soluble polymers upon further decreasing pH. The critical pH's for the formation of soluble and insoluble complexes and...
The solvent dependent photochemistry of fenofibric acid (FA) was studied by femtosecond transient absorption and nanosecond time-resolved resonance Raman experiments and density functional theory calculations. In acetonitrile-rich solution, a typical nπ* triplet state FA ((3)FA) is formed through a highly efficient intersystem crossing and then the (3)FA species undergoes some reaction with water to generate a ketyl radical intermediate at low water concentrations. In contrast, nπ* (3)FA changes from a re...
Clinical outcome and changes in gait pattern after pilon fractures.
PURPOSE: Axial burst fractures of the distal tibia are challenging to treat and often lead to restricted function of the lower limb. The purpose of this study was to investigate the clinical outcome and changes in gait pattern in such patients. METHODS: Thirty-five patients in a level 1 trauma centre were followed up clinically and by gait analysis. The American Orthopaedic Foot and Ankle Society (AOFAS), visual analogue scale (VAS) foot and ankle scale and Phillips scores were applied. Dynamic pedography (...
To examine the unique and additive associations of family functioning and parenting practices with adolescent disordered eating behaviors (i.e., dieting, unhealthy weight control behaviors, binge eating). Data from EAT (Eating and Activity in Teens) 2010, a population-based study assessing eating and activity among racially/ethnically and socio-economically diverse adolescents (n = 2,793; mean age = 14.4, SD = 2.0; age range = 11-19) was used. Logistic regression models were used to examine associat...
Vasectomy is a commonly practiced form of male contraception with over half a million procedures performed annually. Among urologists who perform the procedure, there is considerable variation in pre-procedure patient counseling, vasectomy technique, and post-procedure practices regarding confirmation of sterility. We report an overview of the vasectomy literature published within the past year with a focus on guidelines that have been recently published by two major organizations, the American Urological A...
Revisiting the conformation of xanthan and the effect of industrially relevant treatments.
The structure and conformation of xanthan in aqueous solution following various processing treatments typically encountered in its application were investigated in this study. Treatments such as heating, autoclaving, high pressure homogenisation and irradiation were subjected to the same sample. Parameters such as weight average molecular weight (M(w)), polydispersity index, root mean square radius of gyration, intrinsic viscosity and Huggins constant were used to monitor the effect of these treatments. Add...
Obstructive sleep apnoea (OSA) is associated with increased cardiovascular disease (CVD) risk. In the general population, CVD events peak at 9:00-10:00 AM, associated with diurnal changes in thrombotic potential. However in OSA, these CVD events occur frequently at night. Measuring thrombotic potential across the sleep-wake cycle may provide insight into the temporal association of OSA with CVD. This study aimed to determine diurnal changes in fibrin generation in OSA and whether treatment of OSA with conti...
DNA and protein adducts in human tissues resulting from exposure to tobacco smoke.
Tobacco smoke contains a variety of genotoxic carcinogens that form adducts with DNA and protein in the tissues of smokers. Not only are these biochemical events relevant to the carcinogenic process, but the detection of adducts provides a means of monitoring exposure to tobacco smoke. Characterisation of smoking-related adducts has shed light on the mechanisms of smoking-related diseases and many different types of smoking-derived DNA and protein adducts have been identified. Such approaches also reveal th...
Genome Sequence of Rickettsia australis, the Agent of Queensland Tick Typhus.
Rickettsia australis strain Phillips(T) was isolated in Queensland, Australia, in 1950. It is the tick-borne agent of Queensland tick typhus, a disease endemic in Australia. The 1.29-Mb genome sequence of this bacterium is highly similar to that of Rickettsia akari but contains two plasmids.
Nutrition and depression in the community-based oldest-old.
The number of older adults continues to increase in all healthcare settings. The majority of older adults are living in the community. Most are dealing with at least one chronic physical illness or mental health concern. Nutritional status and depression, key indicators of overall health, have a complex and interdependent relationship. Clinicians must understand factors that affect nutrition and depression to promote positive health outcomes and enhance the overall quality of life for the oldest-old in the...
Super toner and ink repellent superoleophobic surface.
Offset of imaging material from a fuser surface to paper during fusing is highly undesirable in printing. Here the wetting and repellent characteristics of three imaging materials (a solid wax ink, a waxy polyester toner, and a polyester toner) in their molten states have been studied on three model print surfaces: a transparency (surrogate for paper), a PTFE film, and a model superoleophobic surface, with the aim of assessing their performance in fusing. The superoleophobic surface, with water and hexadeca...
The effects of pH and hydrostatic pressure on the reaction of H463F tryptophan indole-lyase (TIL) have been evaluated. The mutant TIL shows very low activity for elimination of indole but is still competent to form a quinonoid intermediate from l-tryptophan [Phillips, R. S., Johnson, N., and Kamath, A. V. (2002) Biochemistry 41, 4012-4019]. Stopped-flow measurements show that the formation of the quinonoid intermediate at 505 nm is affected by pH, with a bell-shaped dependence for the forward rate constant,...
In vivo photoacoustic (PA) and fluorescence flow cytometry were previously applied separately using pulsed and continuous wave lasers respectively, and positive contrast detection mode only. This paper introduces a real-time integration of both techniques with positive and negative contrast modes using only pulsed lasers. Various applications of this new tool are summarized, including detection of liposomes loaded with Alexa-660 dye, red blood cells labeled with Indocyanine Green, B16F10 melanoma cells co-e...
The complexation between bovine serum albumin (BSA) and sugar beet pectin (SBP) was studied in situ by coupling glucono-δ-lactone (GDL) induced acidification with dynamic light scattering and turbidity measurements. Individual measurements at specific pHs and mixing ratios were also carried out using zeta potentiometry, gel permeation chromatography-multiangle laser light scattering (GPC-MALLS), and isothermal titration calorimetry (ITC). These investigations together enabled the establishment of a phase d...
Playing bad cards properly: challenges to improving cure rates in rhabdomyosarcoma.
Technology to Minimize the Morbidity of Le Fort III Osteotomies.
Opioid conjugate vaccines have shown promise in animal models as a potential treatment for opioid addiction. Individual vaccines are quite specific and each targets only a limited number of structurally similar opioids. Since opioid users can switch or transition between opioids, we studied a bivalent immunization strategy of combining 2 vaccines that could target several of the most commonly abused opioids; heroin, oxycodone and their active metabolites. Morphine (M) and oxycodone (OXY) haptens were conjug...
Only a few Armadillo (ARM) repeat proteins have been characterized in plants where they appear to have diverse functions, including the regulation of defence responses. In this study, the identification, cloning and characterization of a gene, encoding an ARM repeat protein (GhARM), is described. GhARM exists as multiple copies in cotton, with an 1713 bp ORF encoding 570 amino acids. The predicted protein contains three consecutive ARM repeats within an Armadillo-type fold, with no other distinguishing dom...