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PubMed Journals Articles About "Qiagen Medical Equipment Deals Alliances Profile Report Updated" RSS

03:36 EDT 23rd September 2017 | BioPortfolio

Qiagen Medical Equipment Deals Alliances Profile Report Updated PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Qiagen Medical Equipment Deals Alliances Profile Report Updated articles that have been published worldwide.

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Showing "Qiagen Medical Equipment Deals Alliances Profile Report Updated" PubMed Articles 1–25 of 25,000+

Divergent Synthesis of Revised Apratoxin E, 30- Epi-apratoxin E and 30S/30R- Oxoapratoxin E.

In this report, originally proposed apratoxin E (30S-7), revised apratoxin E (30R-7), and (30S)/(30R)-oxoapratoxin E (30S)-38/(30R)-38 were efficiently prepared by two synthetic methods. The chiral lactone 10, recycled from the degradation of saponin glycosides, was utilized to prepare the key non-peptide fragment 9. Our alternative convergent assembly strategy was applied to the divergent synthesis of revised apratoxin E and its three analogs. Moreover, ring-closing metathesis (RCM) was first time found to...


Mind the metal: a fragment library-derived zinc impurity binds the E2 ubiquitin-conjugating enzyme Ube2T and induces structural rearrangements.

Efforts to develop inhibitors, activators and effectors of biological reactions using small molecule libraries are often hampered by interference compounds, artifacts and false positives that permeate the pool of initial hits. Here we report the discovery of a promising initial hit compound targeting the Fanconi anemia ubiquitin-conjugating enzyme Ube2T and describe its biophysical and biochemical characterization. Analysis of the co-crystal structure led to the identification of a contaminating zinc ion as...

Entangled Two-Photon Absorption Cross Section on the 808 nm Region for the Common Dyes Zinc Tetraphenylporphyrin and Rhodamine B.

We report the measurement of the entangled two photon absorption (ETPA) cross section, σΕ , at 808 nm on organic chromophores in solution in a low photon flux regime. We performed measurements on Zinc tetraphenylporphyrin (ZnTPP) in Toluene and Rhodamine B (RhB) in Methanol. This is, to the best of our knowledge, the first time that σΕ is measured for RhB. Additionally, we report a study of the dependence of σΕ on the molecular concentration for both molecular systems. In contrast to previous experime...


Energy Gap Law for Exciton Dynamics in Gold Cluster Molecules.

The energy gap law relates the nonradiative decay rate to the energy gap separating the ground and excited states. Here we report that the energy gap law can be applied to exciton dynamics in gold cluster molecules. Size-dependent electrochemical and optical properties were investigated for a series of hexanethiolate-protected gold clusters ranging from Au25 to Au333. Voltammetric studies reveal that the highest occupied molecular orbital-lowest unoccupied molecular orbital (HOMO-LUMO) gaps of these cluster...

Chemical Vapor Deposition of Thin, Conductive and Fouling-Resistant Polymeric Films.

Fouling has been a persistent issue within applications ranging from membrane separation to biomedical implantation. Research to date focuses on fouling resistant coatings, where electrical conductivity is unnecessary. In this study, we report the synthesis of multifunctional thin films with both fouling-resistance and electrical conductivity for their potential applications in electrolysis based self-cleaning of separation membranes and in the field of bioelectronics. This unique combination of properties ...

Electronic Structure and Stability of B12X122- (X=F-At): A Combined Photoelectron Spectroscopic and Theoretical Study.

The stability and electron loss process of numerous Multiply Charged Anions (MCAs) have been traditionally explained in terms of the classical Coulomb interaction between spatially separated charged groups. An understanding of these processes in MCAs with not well-separated excess charges is still lacking. We report the surprising properties and physical behavior of [B12X12]2-, X = F, Cl, Br, I, At, which are MCAs with not well-separated excess charges and cannot be described by the prevailing classical pic...

Environmental Sensitivity in Children: Development of the Highly Sensitive Child Scale and Identification of Sensitivity Groups.

A large number of studies document that children differ in the degree they are shaped by their developmental context with some being more sensitive to environmental influences than others. Multiple theories suggest that Environmental Sensitivity is a common trait predicting the response to negative as well as positive exposures. However, most research to date has relied on more or less proximal markers of Environmental Sensitivity. In this paper we introduce a new questionnaire-the Highly Sensitive Child (H...

Erasing and Blurring Memories: The Differential Impact of Interference on Separate Aspects of Forgetting.

Interference disrupts information processing across many timescales, from immediate perception to memory over short and long durations. The widely held similarity assumption states that as similarity between interfering information and memory contents increases, so too does the degree of impairment. However, information is lost from memory in different ways. For instance, studied content might be erased in an all-or-nothing manner. Alternatively, information may be retained but the precision might be degrad...

Sequential Whole Report Accesses Different States in Visual Working Memory.

Working memory (WM) enables a rapid access to a limited number of items that are no longer physically present. WM studies usually involve the encoding and retention of multiple items, while probing a single item only. Hence, little is known about how well multiple items can be reported from WM. Here we asked participants to successively report each of up to 8 encoded Gabor patches from WM. Recall order was externally cued, and stimulus orientations had to be reproduced on a continuous dimension. Participant...

Pharmacokinetics of a New Amphetamine Extended-Release Oral Suspension in Children with Attention-Deficit/Hyperactivity Disorder.

An extended-release amphetamine (AMP) oral suspension has been developed to facilitate medication ingestion and dose titration. This study sought to determine the pharmacokinetic (PK) profile of this new formulation in children with attention-deficit/hyperactivity disorder (ADHD).

Alan Gregg, the Diary of a Thoughtful Eye-Witness.

After two years of discussions and delays surrounding his eventual departure, Alan Gregg, the 37-year-old associate director of the Rockefeller Foundation's Division of Medical Education (DME), set out from his Paris, France, office in late November 1927, destined for a 17-day trip to Moscow and Leningrad in the Soviet Union. His mission-the first time a Rockefeller officer had ever set foot on Soviet soil(1)-was to gather first-hand knowledge about the state of public health and medical education in Russia...

Nursing and the Public Health Legacies of the Russian Revolution.

The centenary of the October Revolution in 1917 provides a timely opportunity to assess the legacies of that event. I examine the role of the revolution in public health with a focus on nursing, assessing the Imperial Russian health care system, the development of Soviet nursing, and current plans for nursing and public health care in Putin's Russia. Analyzing nursing shows that there was a great deal of continuity in terms of medical personnel and ideas on how public health care service in Russia should op...

Emergency Medical Service Personnel's Risk From Violence While Serving the Community.

To determine the risks of violence-related injury among emergency medical services (EMS) personnel in the United States.

Detecting Spatial Patterns of Disease in Large Collections of Electronic Medical Records Using Neighbor-Based Bootstrapping.

We introduce a method called neighbor-based bootstrapping (NB2) that can be used to quantify the geospatial variation of a variable. We applied this method to an analysis of the incidence rates of disease from electronic medical record data (International Classification of Diseases, Ninth Revision codes) for ∼100 million individuals in the United States over a period of 8 years. We considered the incidence rate of disease in each county and its geospatially contiguous neighbors and rank ordered diseases i...

Differential Programming Needs of College Students Preferring Web-Based Versus In-Person Physical Activity Programs.

College students report several barriers to exercise, highlighting a need for university-based programs that address these challenges. In contrast to in-person interventions, several web-based programs have been developed to enhance program engagement by increasing ease of access and lowering the necessary level of commitment to participate. Unfortunately, web-based programs continue to struggle with engagement and less-than-ideal outcomes. One explanation for this discrepancy is that different intervention...

17β-Estradiol induces proliferation of endometrial NK cells (CD56+) in postmenopausal women.

The aim of this report was to evaluate the impact of hormone replacement therapy (HRT) on lymphocytic infiltration of the endometrium in postmenopausal women.

Tool to assess causality of direct and indirect adverse events associated with therapeutic interventions.

To develop and test a tool to assess causality of direct and indirect adverse events associated with therapeutic interventions. The intervention was one or more drugs and/or natural health products, a device, or practice (professional delivering the intervention).

The importance of calprotectin levels in the obstructive sleep apnea syndrome severity.

Obstructive sleep apnea syndrome (OSAS) is mostly seen in adult populations. It is known that increased levels of several inflammatory mediators play roles in OSAS and related comorbidities. Calprotectin is an inflammatory mediator that increases in some diseases such as Bechet's syndrome, bowel diseases and cardiovascular and cerebrovascular diseases.

Impact of Preexisting Mental Illness on All-Cause and Breast Cancer-Specific Mortality in Elderly Patients With Breast Cancer.

Purpose Limited data are available on the survival of patients with breast cancer with preexisting mental illness, and elderly women are of special interest because they experience the highest incidence of breast cancer. Therefore, we compared all-cause and breast cancer-specific mortality for elderly patients with breast cancer with and without mental illness. Methods A retrospective cohort study was conducted by using SEER-Medicare data, including 19,028 women ≥ 68 years of age who were diagnosed with s...

Decorating and Loading Ghosts with allergens for Allergen Immunotherapy.

More than 25% of the global population suffers from IgE mediated allergic diseases. Allergen immunotherapy (AIT) is the only available form of treatment that alters the underlying mechanism of IgE-mediated allergic diseases. AIT is aimed at desensitizing allergic individuals by repeatedly administering disease-causing allergens over a long period of time. Despite its proven efficacy in numerous clinical trials, the effectiveness of AIT still suffers some drawbacks due to the quality of allergens used and in...

Reconciling conflicting models for global control of cell-cycle transcription.

Models for the control of global cell-cycle transcription have advanced from a CDK-APC/C oscillator, a transcription factor (TF) network, to coupled CDK-APC/C and TF networks. Nonetheless, current models were challenged by a recent study that concluded that the cell-cycle transcriptional program is primarily controlled by a CDK-APC/C oscillator in budding yeast. Here we report an analysis of the transcriptome dynamics in cyclin mutant cells that were not queried in the previous study. We find that B-cyclin ...

Virulence Profile: Mike Kelso.

Medical students' reflections of a post-hospital discharge patient visit.

The Peace and Power Conceptual Model: An Assessment Guide for School Nurses Regarding Commercial Sexual Exploitation of Children.

Human trafficking is a global problem; more than half of all victims are children. In the United States (US), at-risk youth continue to attend school. School nurses are on the frontlines, presenting a window of opportunity to identify and prevent exploitation. Available papers targeting school nurses report that school nurses may lack awareness of commercial sexual exploitation and may have attitudes and misperceptions about behaviors of school children at risk. This is a theoretical paper applying the Peac...

Upper limb hemimelia in a twin pregnancy which was obtained by an ICSI and PGD in a woman with mosaic Turner's syndrome and the prognosis.

Turner's syndrome (TS) is depicted as a total or partial absence of X chromosome, and occurs in approximately 1/2200 of live born females. Generally, mosaic patients are diagnosed following karyotype analysis due to recurrent pregnancy loss, repeated in vitro fertilization (IVF) failure, and a history of malformed babies. The purpose of this case report is to show that even a selection of normal karyotype embryos can result in abnormalities for those with mosaic TS. A 32-year old patient who underwent IVF a...


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