PubMed Journals Articles About "Functional Hybrid Memristor Crossbar Array CMOS System Data" RSS

07:48 EST 21st December 2014 | BioPortfolio

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Showing "Functional Hybrid Memristor Crossbar Array CMOS System Data" PubMed Articles 1–25 of 48,000+

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A new bipolar RRAM selector based on anti-parallel connected diodes for crossbar applications.

Crossbar arrays are the most promising application of a resistive random access memory (RRAM) device for achieving high density memory. However, cross-talk interference in the crossbar array limits the increase in the integration density. In this paper, the combination of two anti-parallel connected diodes and a bipolar RRAM cell is proposed to suppress the sneak current in a crossbar array with anti-parallel connected diodes as the selector for the bipolar RRAM. By using the anti-parallel connected diodes ...

Memristor Crossbar-Based Neuromorphic Computing System: A Case Study.

By mimicking the highly parallel biological systems, neuromorphic hardware provides the capability of information processing within a compact and energy-efficient platform. However, traditional Von Neumann architecture and the limited signal connections have severely constrained the scalability and performance of such hardware implementations. Recently, many research efforts have been investigated in utilizing the latest discovered memristors in neuromorphic systems due to the similarity of memristors to bi...

CMOS Imaging of Pin-Printed Xerogel-Based Luminescent Sensor Microarrays.

We present the design and implementation of a luminescence-based miniaturized multisensor system using pin-printed xerogel materials which act as host media for chemical recognition elements. We developed a CMOS imager integrated circuit (IC) to image the luminescence response of the xerogel-based sensor array. The imager IC uses a 26 × 20 (520 elements) array of active pixel sensors and each active pixel includes a high-gain phototransistor to convert the detected optical signals into electrical currents....

Contact CMOS imaging of gaseous oxygen sensor array.

We describe a compact luminescent gaseous oxygen (O2) sensor microsystem based on the direct integration of sensor elements with a polymeric optical filter and placed on a low power complementary metal-oxide semiconductor (CMOS) imager integrated circuit (IC). The sensor operates on the measurement of excited-state emission intensity of O2-sensitive luminophore molecules tris(4,7-diphenyl-1,10-phenanthroline) ruthenium(II) ([Ru(dpp)3](2+)) encapsulated within sol-gel derived xerogel thin films. The polymeri...

HOPIS: Hybrid Omnidirectional and Perspective Imaging System for Mobile Robots.

In this paper, we present a framework for the hybrid omnidirectional and perspective robot vision system. Based on the hybrid imaging geometry, a generalized stereo approach is developed via the construction of virtual cameras. It is then used to rectify the hybrid image pair using the perspective projection model. The proposed method not only simplifies the computation of epipolar geometry for the hybrid imaging system, but also facilitates the stereo matching between the heterogeneous image formation. Exp...

Inducing microscopic thermal lesions for the dissection of functional cell networks on a chip.

We present a versatile chip-based method to inflict microscopic lesions on cellular networks or tissue models. Our approach relies on resistive heating of microstructured conductors to impose highly localized thermal stress on specific regions of a cell network. We show that networks can be precisely dissected into individual subnetworks using a microwire crossbar array. To this end, we pattern a network of actively beating cardiomyocyte-like cells into smaller subunits by inflicting thermal damage along se...

Progressive Learning Machine: A New Approach for General Hybrid System Approximation.

As the most important property of neural networks (NNs), the universal approximation capability of NNs is widely used in many applications. However, this property is generally proven for continuous systems. Most industrial systems are hybrid systems (e.g., piecewise continuous), which is a significant limitation for real applications. Recently, many identification methods have been proposed for hybrid system approximation; however, these methods only operate in linear hybrid systems. In this paper, the prog...

Fully Integrated CMOS Microsystem for Electrochemical Measurements on 32 × 32 Working Electrodes at 90 Frames Per Second.

Microelectrode arrays offer the potential to electrochemically monitor concentrations of molecules at high spatial resolution. However, current systems are limited in the number of sensor sites, signal resolution, and throughput. Here, we present a fully integrated complementary metal oxide semiconductor (CMOS) system with an array of 32 × 32 working electrodes to perform electrochemical measurements like amperometry and voltammetry. The array consists of platinum electrodes with a center-to-center distanc...

Evaluation of a Hybrid Approach Using UBLAST and BLASTX for Metagenomic Sequences Annotation of Specific Functional Genes.

The fast development of next generation sequencing (NGS) has dramatically increased the application of metagenomics in various aspects. Functional annotation is a major step in the metagenomics studies. Fast annotation of functional genes has been a challenge because of the deluge of NGS data and expanding databases. A hybrid annotation pipeline proposed previously for taxonomic assignments was evaluated in this study for metagenomic sequences annotation of specific functional genes, such as antibiotic resi...

Functional normalization of 450k methylation array data improves replication in large cancer studies.

We propose an extension to quantile normalization that removes unwanted technical variation using control probes. We adapt our algorithm, functional normalization, to the Illumina 450k methylation array and address the open problem of normalizing methylation data with global epigenetic changes, such as human cancers. Using data sets from The Cancer Genome Atlas and a large case-control study, we show that our algorithm outperforms all existing normalization methods with respect to replication of results bet...

New synchronization criteria for memristor-based networks: Adaptive control and feedback control schemes.

In this paper, we investigate synchronization for memristor-based neural networks with time-varying delay via an adaptive and feedback controller. Under the framework of Filippov's solution and differential inclusion theory, and by using the adaptive control technique and structuring a novel Lyapunov functional, an adaptive updated law was designed, and two synchronization criteria were derived for memristor-based neural networks with time-varying delay. By removing some of the basic literature assumptions,...

Projected Hybrid Orbitals: A General QM/MM Method.

A projected hybrid orbital (PHO) method was described to model the covalent boundary in a hybrid quantum mechanical and molecular mechanical (QM/MM) system. The PHO approach can be used in ab initio wave function theory and in density functional theory with any basis set without introducing system-dependent parameters. In this method, a secondary basis set on the boundary atom is introduced to formulate a set of hybrid atomic orbtials. The primary basis set on the boundary atom used for the QM subsystem is ...

An ultrasonic array technique for material characterization of plate samples.

An ultrasonic system with a linear array for characterization of a layered specimen placed in immersion liquid parallel to the aperture of the array is considered. To estimate the longitudinal and transverse wave velocities as well as the thickness and density of the specimen, it is proposed to decompose the spatio-temporal data recorded by the array in a spectrum of plane pulse waves. Based on fitting the developed wave model of the system to the experimental data, it is shown that the relative delays and ...

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Degradation of lindane by a novel embedded bio-nano hybrid system in aqueous environment.

The objective of this study was to evaluate the effect of an embedded bio-nano hybrid system using nanoscale zinc oxide (n-ZnO) and lindane-degrading yeast Candida VITJzN04 for lindane degradation. Nano-embedding of the yeast was done with chemically synthesized n-ZnO particles (50 mg/mL) and was visualized by atomic force microscope (AFM) and scanning electron microscope (SEM). Nanoparticles were embedded substantially on the surfaces of the yeast cells and translocated into the cell cytoplasm without cau...

Full Field Digital Mammography (FFDM) versus CMOS Technology, Specimen Radiography System (SRS) and Tomosynthesis (DBT) - Which System Can Optimise Surgical Therapy?

Aim: This prospective clinical study aimed to evaluate whether it would be possible to reduce the rate of re-excisions using CMOS technology, a specimen radiography system (SRS) or digital breast tomosynthesis (DBT) compared to a conventional full field digital mammography (FFDM) system. Material and Method: Between 12/2012 and 2/2013 50 patients were diagnosed with invasive breast cancer (BI-RADS™ 5). After histological verification, all patients underwent breast-conserving therapy with intraoperative i...

An RF Energy Harvester System Using UHF Micropower CMOS Rectifier Based on a Diode Connected CMOS Transistor.

This paper presents a new type diode connected MOS transistor to improve CMOS conventional rectifier's performance in RF energy harvester systems for wireless sensor networks in which the circuits are designed in 0.18  μ m TSMC CMOS technology. The proposed diode connected MOS transistor uses a new bulk connection which leads to reduction in the threshold voltage and leakage current; therefore, it contributes to increment of the rectifier's output voltage, output current, and efficiency when it is well i...

Ultrasensitive immunoassay based on a pseudobienzyme amplifying system of choline oxidase and luminol-reduced Pt@Au hybrid nanoflowers.

A multi-functional luminol-reduced Pt@Au hybrid flower-like nanocomposite (luminol-Pt@AuNF) which not only acts as an efficient signal probe but also constitutes a pseudobienzyme amplifying system with choline oxidase (ChOx) was firstly synthesized and applied to the construction of a solid-state luminol electrochemiluminescence (ECL) immunosensor for cardiac troponin I (cTnI) detection.

A 256 pixel magnetoresistive biosensor microarray in 0.18μm CMOS.

Magnetic nanotechnologies have shown significant potential in several areas of nanomedicine such as imaging, therapeutics, and early disease detection. Giant magnetoresistive spin-valve (GMR SV) sensors coupled with magnetic nanotags (MNTs) possess great promise as ultra-sensitive biosensors for diagnostics. We report an integrated sensor interface for an array of 256 GMR SV biosensors designed in 0.18 μm CMOS. Arranged like an imager, each of the 16 column level readout channels contains an analog front- ...

A Hybrid EAV-Relational Model for Consistent and Scalable Capture of Clinical Research Data.

Many clinical research databases are built for specific purposes and their design is often guided by the requirements of their particular setting. Not only does this lead to issues of interoperability and reusability between research groups in the wider community but, within the project itself, changes and additions to the system could be implemented using an ad hoc approach, which may make the system difficult to maintain and even more difficult to share. In this paper, we outline a hybrid Entity-Attribute...

Hybrid Algorithms for Multiple Change-Point Detection in Biological Sequences.

Array comparative genomic hybridization (aCGH) is one of the techniques that can be used to detect copy number variations in DNA sequences in high resolution. It has been identified that abrupt changes in the human genome play a vital role in the progression and development of many complex diseases. In this study we propose two distinct hybrid algorithms that combine efficient sequential change-point detection procedures (the Shiryaev-Roberts procedure and the cumulative sum control chart (CUSUM) procedure)...

Split-gene system for hybrid wheat seed production.

Hybrid wheat plants are superior in yield and growth characteristics compared with their homozygous parents. The commercial production of wheat hybrids is difficult because of the inbreeding nature of wheat and the lack of a practical fertility control that enforces outcrossing. We describe a hybrid wheat system that relies on the expression of a phytotoxic barnase and provides for male sterility. The barnase coding information is divided and distributed at two loci that are located on allelic positions of ...

New challenges and perspectives in nuclear medicine imaging.

Hybrid positron emission tomography/computer tomography (PET/CT) and single photon emission computer tomography/computer tomography (SPECT/CT) have resulted in significant advances both in medical research and routine clinical use. The most recent multimodality system that combines PET and magnetic resonance imaging (MRI) offers new potentials unthinkable before. The hybrid techniques allow obtaining simultaneous morphologic, functional, and molecular information of a living system. The proper use of multim...

Yeast Two-Hybrid System for Dissecting the Rice MAPK Interactome.

Protein-protein interactions are a preliminary but fundamental key to many biological systems. Identification of proteins that interact with particular bait not only contributes to a deeper understanding of bait protein function but also provides much information for the discovery of larger-scale interaction networks (interactome). Therefore, protein-protein interaction mapping is regarded as a widely accepted standardized functional genomics technique that provides comprehensive functional interpretation o...

A Distributed Amplifier System for Bilayer Lipid Membrane (BLM) Arrays With Noise and Individual Offset Cancellation.

Lipid bilayer membrane (BLM) arrays are required for high throughput analysis, for example drug screening or advanced DNA sequencing. Complex microfluidic devices are being developed but these are restricted in terms of array size and structure or have integrated electronic sensing with limited noise performance. We present a compact and scalable multichannel electrophysiology platform based on a hybrid approach that combines integrated state-of-the-art microelectronics with low-cost disposable fluidics pro...

Innovative design of light collimator based on a freeform microlens array.

In developing a daylighting system, the overall system efficiency is crucial. In the daylighting system, whether the light propagates parallel strongly affects the efficiency. In this paper, we simulate a multicurvature lens to collimate rays propagated from different angles. We describe a method based on a freeform microlens array, which increases transmission efficiency. Results show that with the freeform microlens array collimator, the light propagates provide at least 50.26% parallel and the efficiency...


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