PubMed Journals Articles About "Functional Hybrid Memristor Crossbar Array CMOS System Data" RSS

22:54 EDT 20th April 2015 | BioPortfolio

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Showing "Functional Hybrid Memristor Crossbar Array CMOS System Data" PubMed Articles 1–25 of 48,000+

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Memristor Crossbar-Based Neuromorphic Computing System: A Case Study.

By mimicking the highly parallel biological systems, neuromorphic hardware provides the capability of information processing within a compact and energy-efficient platform. However, traditional Von Neumann architecture and the limited signal connections have severely constrained the scalability and performance of such hardware implementations. Recently, many research efforts have been investigated in utilizing the latest discovered memristors in neuromorphic systems due to the similarity of memristors to bi...

Memristor-Based Multilayer Neural Networks With Online Gradient Descent Training.

Learning in multilayer neural networks (MNNs) relies on continuous updating of large matrices of synaptic weights by local rules. Such locality can be exploited for massive parallelism when implementing MNNs in hardware. However, these update rules require a multiply and accumulate operation for each synaptic weight, which is challenging to implement compactly using CMOS. In this paper, a method for performing these update operations simultaneously (incremental outer products) using memristor-based arrays i...

HOPIS: Hybrid Omnidirectional and Perspective Imaging System for Mobile Robots.

In this paper, we present a framework for the hybrid omnidirectional and perspective robot vision system. Based on the hybrid imaging geometry, a generalized stereo approach is developed via the construction of virtual cameras. It is then used to rectify the hybrid image pair using the perspective projection model. The proposed method not only simplifies the computation of epipolar geometry for the hybrid imaging system, but also facilitates the stereo matching between the heterogeneous image formation. Exp...

A Bio-Hybrid Tactile Sensor Incorporating Living Artificial Skin and an Impedance Sensing Array.

The development of a bio-hybrid tactile sensor array that incorporates a skin analogue comprised of alginate encapsulated fibroblasts is described. The electrical properties are modulated by mechanical stress induced during contact, and changes are detected by a ten-channel dual-electrode impedance sensing array. By continuously monitoring the impedance of the sensor array at a fixed frequency, whilst normal and tangential loads are applied to the skin surface, transient mechanotransduction has been observe...

An Ultra-Low Power CMOS Image Sensor with On-Chip Energy Harvesting and Power Management Capability.

An ultra-low power CMOS image sensor with on-chip energy harvesting and power management capability is introduced in this paper. The photodiode pixel array can not only capture images but also harvest solar energy. As such, the CMOS image sensor chip is able to switch between imaging and harvesting modes towards self-power operation. Moreover, an on-chip maximum power point tracking (MPPT)-based power management system (PMS) is designed for the dual-mode image sensor to further improve the energy efficiency...

Inducing microscopic thermal lesions for the dissection of functional cell networks on a chip.

We present a versatile chip-based method to inflict microscopic lesions on cellular networks or tissue models. Our approach relies on resistive heating of microstructured conductors to impose highly localized thermal stress on specific regions of a cell network. We show that networks can be precisely dissected into individual subnetworks using a microwire crossbar array. To this end, we pattern a network of actively beating cardiomyocyte-like cells into smaller subunits by inflicting thermal damage along se...

Progressive Learning Machine: A New Approach for General Hybrid System Approximation.

As the most important property of neural networks (NNs), the universal approximation capability of NNs is widely used in many applications. However, this property is generally proven for continuous systems. Most industrial systems are hybrid systems (e.g., piecewise continuous), which is a significant limitation for real applications. Recently, many identification methods have been proposed for hybrid system approximation; however, these methods only operate in linear hybrid systems. In this paper, the prog...

Fully Integrated CMOS Microsystem for Electrochemical Measurements on 32 × 32 Working Electrodes at 90 Frames Per Second.

Microelectrode arrays offer the potential to electrochemically monitor concentrations of molecules at high spatial resolution. However, current systems are limited in the number of sensor sites, signal resolution, and throughput. Here, we present a fully integrated complementary metal oxide semiconductor (CMOS) system with an array of 32 × 32 working electrodes to perform electrochemical measurements like amperometry and voltammetry. The array consists of platinum electrodes with a center-to-center distanc...

Experimental Demonstration of a Second-Order Memristor and Its Ability to Biorealistically Implement Synaptic Plasticity.

Memristors have been extensively studied for data storage and low-power computation applications. In this study, we show that memristors offer more than simple resistance change. Specifically, the dynamic evolutions of internal state variables allow an oxide-based memristor to exhibit Ca2+ like dynamics that natively encode timing information and regulate synaptic weights. Such a device can be modeled as a second-order memristor, and allow the implementation of critical synaptic functions realistically usin...

Fourier transform acousto-optic imaging with a custom-designed CMOS smart-pixels array.

We report acousto-optic imaging (AOI) into a scattering medium using a Fourier Transform (FT) analysis to achieve axial resolution. The measurement system was implemented using a CMOS smart-pixels sensor dedicated to the real-time analysis of speckle patterns. This first proof-of-principle of FT-AOI demonstrates some of its potential advantages, with a signal-to-noise ratio comparable to the one obtained without axial resolution, and with an acquisition rate compatible with a use on living biological tissue...

Evaluation of a Hybrid Approach Using UBLAST and BLASTX for Metagenomic Sequences Annotation of Specific Functional Genes.

The fast development of next generation sequencing (NGS) has dramatically increased the application of metagenomics in various aspects. Functional annotation is a major step in the metagenomics studies. Fast annotation of functional genes has been a challenge because of the deluge of NGS data and expanding databases. A hybrid annotation pipeline proposed previously for taxonomic assignments was evaluated in this study for metagenomic sequences annotation of specific functional genes, such as antibiotic resi...

Functional normalization of 450k methylation array data improves replication in large cancer studies.

We propose an extension to quantile normalization that removes unwanted technical variation using control probes. We adapt our algorithm, functional normalization, to the Illumina 450k methylation array and address the open problem of normalizing methylation data with global epigenetic changes, such as human cancers. Using data sets from The Cancer Genome Atlas and a large case-control study, we show that our algorithm outperforms all existing normalization methods with respect to replication of results bet...

Functional normalization of 450k methylation array data improves replication in large cancer studies.

We propose an extension to quantile normalization that removes unwanted technical variation using control probes. We adapt our algorithm, functional normalization, to the Illumina 450k methylation array and address the open problem of normalizing methylation data with global epigenetic changes, such as human cancers. Using data sets from The Cancer Genome Atlas and a large case-control study, we show that our algorithm outperforms all existing normalization methods with respect to replication of results bet...

Projected Hybrid Orbitals: A General QM/MM Method.

A projected hybrid orbital (PHO) method was described to model the covalent boundary in a hybrid quantum mechanical and molecular mechanical (QM/MM) system. The PHO approach can be used in ab initio wave function theory and in density functional theory with any basis set without introducing system-dependent parameters. In this method, a secondary basis set on the boundary atom is introduced to formulate a set of hybrid atomic orbtials. The primary basis set on the boundary atom used for the QM subsystem is ...

An ultrasonic array technique for material characterization of plate samples.

An ultrasonic system with a linear array for characterization of a layered specimen placed in immersion liquid parallel to the aperture of the array is considered. To estimate the longitudinal and transverse wave velocities as well as the thickness and density of the specimen, it is proposed to decompose the spatio-temporal data recorded by the array in a spectrum of plane pulse waves. Based on fitting the developed wave model of the system to the experimental data, it is shown that the relative delays and ...

Finite-time synchronization control of a class of memristor-based recurrent neural networks.

This paper presents a global and local finite-time synchronization control law for memristor neural networks. By utilizing the drive-response concept, differential inclusions theory, and Lyapunov functional method, we establish several sufficient conditions for finite-time synchronization between the master and corresponding slave memristor-based neural network with the designed controller. In comparison with the existing results, the proposed stability conditions are new, and the obtained results extend so...

Degradation of lindane by a novel embedded bio-nano hybrid system in aqueous environment.

The objective of this study was to evaluate the effect of an embedded bio-nano hybrid system using nanoscale zinc oxide (n-ZnO) and lindane-degrading yeast Candida VITJzN04 for lindane degradation. Nano-embedding of the yeast was done with chemically synthesized n-ZnO particles (50 mg/mL) and was visualized by atomic force microscope (AFM) and scanning electron microscope (SEM). Nanoparticles were embedded substantially on the surfaces of the yeast cells and translocated into the cell cytoplasm without cau...

New challenges and new potentials in the management of patients in oncology: PET/MRI clinical applications.

The most recent multimodality technique, the hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) combines two very different technologies, which is a great result of human creativity. The combined PET/MRI has significant potentials in clinical oncology providing new perspectives of functional and anatomical information. PET/MRI offers simultaneous measurements of multifunctional data such as PET mapping by different specific tracers or MRI morphologic, MR molecular (MR spectroscopy, MRS...

Relevant

New synchronization criteria for memristor-based networks: Adaptive control and feedback control schemes.

In this paper, we investigate synchronization for memristor-based neural networks with time-varying delay via an adaptive and feedback controller. Under the framework of Filippov's solution and differential inclusion theory, and by using the adaptive control technique and structuring a novel Lyapunov functional, an adaptive updated law was designed, and two synchronization criteria were derived for memristor-based neural networks with time-varying delay. By removing some of the basic literature assumptions,...

Ultrasensitive immunoassay based on a pseudobienzyme amplifying system of choline oxidase and luminol-reduced Pt@Au hybrid nanoflowers.

A multi-functional luminol-reduced Pt@Au hybrid flower-like nanocomposite (luminol-Pt@AuNF) which not only acts as an efficient signal probe but also constitutes a pseudobienzyme amplifying system with choline oxidase (ChOx) was firstly synthesized and applied to the construction of a solid-state luminol electrochemiluminescence (ECL) immunosensor for cardiac troponin I (cTnI) detection.

An Analog-Digital Hybrid RX Beamformer Chip With Non-Uniform Sampling for Ultrasound Medical Imaging With 2D CMUT Array.

To reduce the memory area, a two-stage RX beamformer (BF) chip with 64 channels is proposed for the ultrasound medical imaging with a 2D CMUT array. The chip retrieved successfully two B-mode phantom images with a steering angle from -45 (°) to +45 (°), the maximum delay range of 8 μs, and the delay resolution of 6.25 ns. An analog-digital hybrid BF (HBF) is chosen for the proposed chip to utilize the easy beamforming operation in the digital domain and also to reduce chip area by minimizing the number o...

A Hybrid EAV-Relational Model for Consistent and Scalable Capture of Clinical Research Data.

Many clinical research databases are built for specific purposes and their design is often guided by the requirements of their particular setting. Not only does this lead to issues of interoperability and reusability between research groups in the wider community but, within the project itself, changes and additions to the system could be implemented using an ad hoc approach, which may make the system difficult to maintain and even more difficult to share. In this paper, we outline a hybrid Entity-Attribute...

A Biological-Realtime Neuromorphic System in 28 nm CMOS Using Low-Leakage Switched Capacitor Circuits.

A switched-capacitor (SC) neuromorphic system for closed-loop neural coupling in 28 nm CMOS is presented, occupying 600 um by 600 um. It offers 128 input channels (i.e., presynaptic terminals), 8192 synapses and 64 output channels (i.e., neurons). Biologically realistic neuron and synapse dynamics are achieved via a faithful translation of the behavioural equations to SC circuits. As leakage currents significantly affect circuit behaviour at this technology node, dedicated compensation techniques are employ...

A Dual-mode Large-arrayed CMOS ISFET Sensor for Accurate and High-throughput pH Sensing in Biomedical Diagnosis.

The existing ISFET based DNA sequencing detects hydrogen ions released during polymerization of DNA strands on microbeads, which are scattered into microwell array above the ISFET sensor with unknown distribution. However, false pH detection happens at empty microwells due to cross-talk from neighbouring microbeads. In this paper, a dual-mode CMOS ISFET sensor is proposed to have accurate pH detection towards DNA sequencing.

Hybrid Algorithms for Multiple Change-Point Detection in Biological Sequences.

Array comparative genomic hybridization (aCGH) is one of the techniques that can be used to detect copy number variations in DNA sequences in high resolution. It has been identified that abrupt changes in the human genome play a vital role in the progression and development of many complex diseases. In this study we propose two distinct hybrid algorithms that combine efficient sequential change-point detection procedures (the Shiryaev-Roberts procedure and the cumulative sum control chart (CUSUM) procedure)...


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