PubMed Journals Articles About "Photosensitivity Current Biological Overview" RSS

16:22 EDT 30th May 2015 | BioPortfolio

Photosensitivity Current Biological Overview PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Photosensitivity Current Biological Overview articles that have been published worldwide.

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Showing "Photosensitivity current biological overview" PubMed Articles 1–25 of 21,000+


Diabetic pregnancy: an overview of current guidelines and clinical practice.

We review the recent changes in diagnostic criteria of gestational diabetes mellitus (GDM), describe problems with maintaining and monitoring adequate blood glucose, especially in type 1 diabetes, and provide a brief overview of the currently approved glucose-lowering therapies in pregnancy.

An overview of microRNAs.

The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in molecular biology. There are now over 2000 miRNAs that have been discovered in humans and it is believed that they collectively regulate one third of the genes in the genome. miRNAs have been linked to many human diseases and are being pursued as clinical diagnostics and as therapeutic targets. This review presents an overview of the miRNA pathway, including biogenesis routes, biological roles, and clinical approaches.

Overview of Binding Free Energy Calculation Techniques for Elucidation of Biological Processes and for Drug Discovery.

The elucidation of the interactions between a protein and a ligand or proteins is a key issue for understanding of functional processes of various proteins, enzymes and receptors in biological organisms, system biology and drug design. One of the most important matters in these problems is the accurate estimation of binding free energy between a protein and a ligand or proteins. In the present review, we overview various techniques and introduce a new technique for estimation of binding free energy calculat...

Glioma: an overview of current classifications, characteristics, molecular biology and target therapies.

  Glioma is the most common primary brain tumor, accounting for 30% to 40% of all intracranial tumors. About half of all gliomas in adults are glioblastomas. Patients with glioblastoma have a poor prognosis, with a median survival of one year despite aggressive therapy and a five year mortality of over 95%. Although considerable progress has been made in the technical proficiencies of surgical and radiation oncology, the overall impact of these advances on clinical outcomes has been disappointing. Recent e...

Overview of the International Society for Biological and Environmental Repositories (ISBER) Working Groups.

An Improved Method for Completely Uncertain Biological Network Alignment.

With the continuous development of biological experiment technology, more and more data related to uncertain biological networks needs to be analyzed. However, most of current alignment methods are designed for the deterministic biological network. Only a few can solve the probabilistic network alignment problem. However, these approaches only use the part of probabilistic data in the original networks allowing only one of the two networks to be probabilistic. To overcome the weakness of current approaches,...

Current status and future prospects of mass spectrometry imaging of small molecules.

In the field of small-molecule studies, vast efforts have been put forth in order to comprehensively characterize and quantify metabolites formed from complex mechanistic pathways within biochemical and biological organisms. Many technologies and methodologies have been developed to aid understanding of the inherent complexities within biological metabolomes. Specifically, mass spectroscopy imaging (MSI) has emerged as a foundational technique in gaining insight into the molecular entities within cells, tis...

Molecular simulations and visualization: introduction and overview.

Here we provide an introduction and overview of current progress in the field of molecular simulation and visualization, touching on the following topics: (1) virtual and augmented reality for immersive molecular simulations; (2) advanced visualization and visual analytic techniques; (3) new developments in high performance computing; and (4) applications and model building.

Towards understanding of nanoparticle-protein corona.

With the rapid developments of nanotechnology, chances of exposing nanoscale particles to humans (e.g., workers and consumers) also increase correspondingly, which raises serious concerns on their biosafety. Entrance of nanoparticles into diverse biological environment endows them with new and dynamic biological identities as the so-called nanoparticle-protein corona. Therefore, understanding the role of these nanoparticle-protein coronas and resulting biological responses is crucial, as it helps to clarify...

Overview of polycystic kidney disease in children.

Editorial overview: Preventive and therapeutic vaccines (B cell epitope vaccine).

Aromatic abietane diterpenoids: their biological activity and synthesis.

Covering: 1980s-2014In this study, the biological properties of natural abietane-type diterpenoids with an aromatic C ring are reviewed. An overview of the synthetic studies of this group of abietanes, including dehydroabietic acid, callitrisic acid and ferruginol, is presented. The review contains about 160 references.

Disordered eating in obese individuals.

This article provides an overview of current thinking about the association between disordered eating and obesity, emphasizing binge eating, binge eating disorder and food addiction as useful conceptual models.

Editorial overview: Folding and binding: Old concepts, new ideas, novel insights.

Biological Messiness vs. Biological Genius: Mechanistic Aspects and Roles of Protein Promiscuity.

In contrast to the traditional biological paradigms focused on 'specificity,' recent research and theoretical efforts have focused on functional 'promiscuity' exhibited by proteins and enzymes in many biological settings, including enzymatic detoxication, steroid biochemistry, signal transduction and immune responses. In addition, divergent evolutionary processes are apparently facilitated by random mutations that yield promiscuous enzyme intermediates. The intermediates, in turn, provide opportunities for ...

Update on belimumab for the management of systemic lupus erythematosus.

Introduction: Belimumab is a fully humanised mAb against B lymphocyte stimulator (B-LyS). It is the first biological drug to be licensed and approved by the US FDA and the European Medicines Evaluation Agency for use in combination with standard immunosuppressants in autoantibody-positive systemic lupus erythematosus (SLE). The clinical effectiveness and impact of this drug on lupus morbidity and mortality is evaluated in this review. Areas covered: An overview of the efficacy and safety of belimumab based ...

An novel frequent probability pattern mining algorithm based on circuit simulation method in uncertain biological networks.

Motif mining has always been a hot research topic in bioinformatics. Most of current research on biological networks focuses on exact motif mining. However, due to the inevitable experimental error and noisy data, biological network data represented as the probability model could better reflect the authenticity and biological significance, therefore, it is more biological meaningful to discover probability motif in uncertain biological networks. One of the key steps in probability motif mining is frequent p...

Editorial overview: Carbohydrate-protein interactions: The future is taking shape.

ERCC6 dysfunction presenting as progressive neurological decline with brain hypomyelination.

Mutations in ERCC6 are associated with growth failure, intellectual disability, neurological dysfunction and deterioration, premature aging, and photosensitivity. We describe siblings with biallelic ERCC6 mutations (NM_000124.2:c. [543 + 4delA];[2008C > T]) and brain hypomyelination, microcephaly, cognitive decline, and skill regression but without photosensitivity or progeria. DNA repair assays on cultured skin fibroblasts confirmed a defect of transcription-coupled nucleotide excision repair and i...

An overview of biological production of L-theanine.

L-Theanine (γ-glutamylethylamide) is a unique non-protein amino acid that is naturally found in tea plants. It contributes to the umami taste and unique flavor to green tea infusion, and thus its content in tea leaves highly impacts the tea quality and price. In addition to the graceful taste, it has been proved to have many beneficial physiological effects, especially promoting relaxation and improving concentration and learning ability. Based on these promising advantages, L-theanine has been commerciall...

Genetics of vasculitis.

We aim to give an overview of the recent progress in the knowledge of the genetic component of vasculitides.

Metabolomics as a tool in nutritional research.

Metabolomics is emerging as a powerful tool for studying metabolic processes and in recent years, the applications in the area of nutrition have risen rapidly. The present review gives an overview of the current applications in the field of nutrition and identifies areas in need of advancement.

Extending the Clinical Horizons of Mucosal Bacterial Vaccines: Current Evidence and Future Prospects.

Antibiotics remain the mainstay of treatment for infectious diseases, but the growing frequency of antibiotic resistance represents a major concern for healthcare worldwide. The use of antibiotics in recurrent infections raises other issues, such as their limitations for treating diverse microorganisms, deleterious effects on the microbiota of the patient and potential adverse effects. In recent years, progress has been made towards the development of novel polybacterial vaccines administered via the mucosa...

Vitamin D supplementation in the ICU patient.

Recent findings suggest that vitamin D is a marker for outcomes in critical illness. The purpose of this review is to summarize current biological, observational and interventional evidence in the critically ill.

Magnetic and noble metal nanocomposites for separation and optical detection of biological species.

Nanoalloys and nanocomposites are widely studied classes of nanomaterials within the context of biological systems. They are of immense interest because of the possibility of tuning the optical, magnetic, electronic and chemical properties through particle composition and internal architecture. In principle these properties can therefore be optimized for application in biological detections such as of DNA sequences, bacteria, viruses, antibodies, antigens, and cancer cells. This article presents an overview...

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