PubMed Journals Articles About "Photosensitivity Current Biological Overview" RSS

08:56 EDT 30th March 2015 | BioPortfolio

Photosensitivity Current Biological Overview PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Photosensitivity Current Biological Overview articles that have been published worldwide.

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Showing "Photosensitivity current biological overview" PubMed Articles 1–25 of 21,000+

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Diabetic pregnancy: an overview of current guidelines and clinical practice.

We review the recent changes in diagnostic criteria of gestational diabetes mellitus (GDM), describe problems with maintaining and monitoring adequate blood glucose, especially in type 1 diabetes, and provide a brief overview of the currently approved glucose-lowering therapies in pregnancy.

Neurobiology: The Eye within the Brain.

All vertebrates except mammals have photoreceptors within their brains; however, the light-sensitive cells have never been unambiguously identified. A new paper provides direct evidence of photosensitivity in cerebrospinal fluid (CSF)-contacting neurons in quail brain that mediate the seasonal reproductive response.

Intrinsic photosensitivity of a deep brain photoreceptor.

In addition to having a photoreceptive retina and pineal organ, non-mammalian vertebrates are known to have photoreceptors in the deeper regions of the brain that mediate seasonal changes in physiology and behavior [1]. Cerebrospinal fluid (CSF)-contacting neurons extend knob-like dendrites into the ventricular cavity, where they form ciliated terminals [2]. The dendritic structures of photoreceptor cells in the developing retina and the pineal organ resemble those of CSF-contacting neurons. Thus, CSF-conta...

Oligopeptides as Biomarkers of Cyanobacterial Subpopulations. Toward an Understanding of Their Biological Role.

Cyanobacterial oligopeptides comprise a wide range of bioactive and/or toxic compounds. While current research is strongly focused on exploring new oligopeptide variants and their bioactive properties, the biological role of these compounds remains elusive. Oligopeptides production abilities show a remarkably patchy distribution among conspecific strains. This observation has prompted alternative approaches to unveil their adaptive value, based on the use of cellular oligopeptide compositions as biomarkers ...

Overview of Binding Free Energy Calculation Techniques for Elucidation of Biological Processes and for Drug Discovery.

The elucidation of the interactions between a protein and a ligand or proteins is a key issue for understanding of functional processes of various proteins, enzymes and receptors in biological organisms, system biology and drug design. One of the most important matters in these problems is the accurate estimation of binding free energy between a protein and a ligand or proteins. In the present review, we overview various techniques and introduce a new technique for estimation of binding free energy calculat...

Editorial overview: Nanobiotechnology.

Overview of the International Society for Biological and Environmental Repositories (ISBER) Working Groups.

Current status and future prospects of mass spectrometry imaging of small molecules.

In the field of small-molecule studies, vast efforts have been put forth in order to comprehensively characterize and quantify metabolites formed from complex mechanistic pathways within biochemical and biological organisms. Many technologies and methodologies have been developed to aid understanding of the inherent complexities within biological metabolomes. Specifically, mass spectroscopy imaging (MSI) has emerged as a foundational technique in gaining insight into the molecular entities within cells, tis...

Human variome project - current overview.

Molecular simulations and visualization: introduction and overview.

Here we provide an introduction and overview of current progress in the field of molecular simulation and visualization, touching on the following topics: (1) virtual and augmented reality for immersive molecular simulations; (2) advanced visualization and visual analytic techniques; (3) new developments in high performance computing; and (4) applications and model building.

Towards understanding of nanoparticle-protein corona.

With the rapid developments of nanotechnology, chances of exposing nanoscale particles to humans (e.g., workers and consumers) also increase correspondingly, which raises serious concerns on their biosafety. Entrance of nanoparticles into diverse biological environment endows them with new and dynamic biological identities as the so-called nanoparticle-protein corona. Therefore, understanding the role of these nanoparticle-protein coronas and resulting biological responses is crucial, as it helps to clarify...

Overview of polycystic kidney disease in children.

Acute Phototoxic Reaction in a Century Cyclist.

: Medications can cause photosensitivity. Several of these medications, specifically the nonsteroidal anti-inflammatory medications (NSAIDs), may be taken by athletes to treat joint and muscle discomfort. Many athletic events occur outdoors, which in turn exposes athletes to sunlight. Athletes taking NSAIDs and performing extensive outdoor activities may be at higher risk for phototoxic drug reactions. Clinicians may wish consider the potential for patient photosensitivity when recommending prescription and...

Genome scale modeling in systems biology: algorithms and resources.

In recent years, in silico studies and trial simulations have complemented experimental procedures. A model is a description of a system, and a system is any collection of interrelated objects; an object, moreover, is some elemental unit upon which observations can be made but whose internal structure either does not exist or is ignored. Therefore, any network analysis approach is critical for successful quantitative modeling of biological systems. This review highlights some of most popular and important m...

Biological findings from the recent NMR-based studies of glycosaminoglycanprotein interactions.

Besides regulating multiple physiological processes like cellular growth, migration and differentiation, glycosaminoglycans (GAGs) are also largely explored in the global market as clinical or nutraceutical agents. Generally, these physiological and biomedical events are ultimately triggered by the quality and nature of molecular interactions between GAGs and functional proteins. Nuclear magnetic resonance (NMR) spectroscopy participates significantly in the investigations of the most carbohydrate-protein i...

Editorial overview: Theory and simulation: Macromolecular machines.

Editorial overview: Immune senescence: Known knowns and unknown unknowns.

Editorial overview: Developmental mechanisms, patterning and evolution.

Aromatic abietane diterpenoids: their biological activity and synthesis.

Covering: 1980s-2014In this study, the biological properties of natural abietane-type diterpenoids with an aromatic C ring are reviewed. An overview of the synthetic studies of this group of abietanes, including dehydroabietic acid, callitrisic acid and ferruginol, is presented. The review contains about 160 references.

Disordered eating in obese individuals.

This article provides an overview of current thinking about the association between disordered eating and obesity, emphasizing binge eating, binge eating disorder and food addiction as useful conceptual models.

Photosensitivity Induced by Mesalazine: Report of a Case.

ERCC6 dysfunction presenting as progressive neurological decline with brain hypomyelination.

Mutations in ERCC6 are associated with growth failure, intellectual disability, neurological dysfunction and deterioration, premature aging, and photosensitivity. We describe siblings with biallelic ERCC6 mutations (NM_000124.2:c. [543 + 4delA];[2008C > T]) and brain hypomyelination, microcephaly, cognitive decline, and skill regression but without photosensitivity or progeria. DNA repair assays on cultured skin fibroblasts confirmed a defect of transcription-coupled nucleotide excision repair and i...

Biological Messiness vs. Biological Genius: Mechanistic Aspects and Roles of Protein Promiscuity.

In contrast to the traditional biological paradigms focused on 'specificity,' recent research and theoretical efforts have focused on functional 'promiscuity' exhibited by proteins and enzymes in many biological settings, including enzymatic detoxication, steroid biochemistry, signal transduction and immune responses. In addition, divergent evolutionary processes are apparently facilitated by random mutations that yield promiscuous enzyme intermediates. The intermediates, in turn, provide opportunities for ...

Photosensitivity in mild traumatic brain injury (mTBI): A retrospective analysis.

Abstract Primary objective: To determine whether photosensitivity (PS) changes over time and, if so, what factors may be related to the change; furthermore, to determine whether tint density changes over time, all in mild traumatic brain injury (mTBI). Design and methods: A retrospective analysis of 62 patient records (aged 18-40 years) with mTBI and PS was conducted. All charts were obtained from the SUNY/College of Optometry clinics from 2004-2011. Results: Fifty per cent demonstrated reduced PS over time...

Update on belimumab for the management of systemic lupus erythematosus.

Introduction: Belimumab is a fully humanised mAb against B lymphocyte stimulator (B-LyS). It is the first biological drug to be licensed and approved by the US FDA and the European Medicines Evaluation Agency for use in combination with standard immunosuppressants in autoantibody-positive systemic lupus erythematosus (SLE). The clinical effectiveness and impact of this drug on lupus morbidity and mortality is evaluated in this review. Areas covered: An overview of the efficacy and safety of belimumab based ...


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