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The research hypothesis for the proposed study asks the question, can Asmanex® demonstrate comparable anti-inflammatory therapeutic efficacy to the combination product, Advair® in control of mild persistent asthma?
The purpose is to demonstrate that the anti-inflammatory protection afforded by monotherapy with an inhaled steroid (Asmanex®) is comparable to combination therapy with Advair® 100/50, when measured by this standard methodology (methacholine bronchoprovocation) in subjects with mild persistent asthma.
Allocation: Randomized, Control: Active Control, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Treatment
Mometasone or Advair
Johns Hopkins Asthma and Allergy Center
Johns Hopkins University
Published on BioPortfolio: 2014-08-27T03:39:03-0400
Collect PK/PD data for this age group to compare ADVAIR DISKUS with ADVAIR HFA
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Drugs that are used to treat asthma.
A beta-adrenergic agonist used in the treatment of asthma and bronchospasms.
An adrenergic beta-agonist used as a bronchodilator agent in asthma therapy.
Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma.
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