Risk Stratification of Non ST Elevation ACS With Computed Tomographic Angiography (REACT)
Summary
The purpose of this project is to examine the effectiveness of computed tomographic angiography (CTA) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS). People who are hospitalized with this situation often require an angiogram to assess the heart and its arteries.
Recent advancements in technology have enabled CTA to clearly define coronary artery anatomy with great accuracy and to guide treatment strategies in select patient populations. We are investigating that CTA may be used, as an alternative to conventional angiograms, for the risk stratification of patients with high risk NSTE-ACS.
Patients eligible for the study will be high risk NSTE-ACS and awaiting an angiogram. Enrolled patients will undergo CTA prior to the angiogram. With each CTA the patient will be injected with a small dose of an X-ray dye and will be asked to lie still on the "scanning bed" for a period of 5-10 minutes.
Study Design
Allocation: Non-Randomized, Control: Uncontrolled, Intervention Model: Single Group Assignment, Masking: Single Blind, Primary Purpose: Diagnostic
Conditions
Acute Coronary Syndrome
Intervention
Computed Tomographic Angiography
Location
University of Ottawa Heart Institute
Ottawa
Ontario
Canada
K1Y 4W7
Status
Recruiting
Source
University of Ottawa Heart Institute
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00449826
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Colonography, Computed Tomographic
A non-invasive imaging method that uses computed tomographic data combined with specialized imaging software to examine the colon.
Four-dimensional Computed Tomography
Three-dimensional computed tomographic imaging with the added dimension of time, to follow motion during imaging.
Pancreatitis
INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
Coronary Angiography
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Coronary Aneurysm
Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.
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