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Cognitive Impairment Following Sedation for Colonoscopy With Propofol, Midazolam and Fentanyl Combinations

2014-08-27 03:39:43 | BioPortfolio

Summary

Our hypothesis is that adding midazolam and/or fentanyl to propofol sedation for elective outpatient colonoscopy increases cognitive impairment at hospital discharge without improving intraoperative conditions or reducing intraoperative side-effects.

200 healthy patients aged 18 years or older will be randomised to receive propofol or propofol plus midazolam and/or fentanyl. Cognitive impairment will be tested at hospital discharge using Cogstate computerised testing software.

Study Design

Allocation: Randomized, Control: Active Control, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention

Conditions

Cognitive Impairment

Intervention

Propofol, midazolam, fentanyl

Location

Royal Melbourne Hospital
Parkville
Victoria
Australia
3050

Status

Recruiting

Source

Melbourne Health

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:39:43-0400

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