Labetalol to Prevent Hypertension and Tachycardia During Fiberoptic Bronchoscopy
Summary
Passing a bronchoscope through the airways frequently causes a stress response even though patients are sedated. This stress response is usually an increase in pulse and blood pressure, which may have undesirable effects on the heart and circulation.
We plan to give patients labetalol (a beta blocker which reduces pulse and blood pressure) in addition to normal sedation, to patients undergoing bronchoscopy in our department.
Study Design
Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment
Conditions
Bronchoscopy
Intervention
Labetalol 10mg iv
Location
Rabin Medical Center
Petach Tikva
Israel
49100
Status
Completed
Source
Rabin Medical Center
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00394537
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Bronchoscopy
Endoscopic examination, therapy or surgery of the bronchi.
Labetalol
Blocker of both alpha- and beta-adrenergic receptors that is used as an antihypertensive.
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PubMed Articles
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