Beta Blocker for Chronic Wound Healing

20:47 EDT 19th April 2015 | BioPortfolio

Summary

The purpose of this study is to evaluate the efficacy and safety of treatment of chronic cutaneous ulcers and burn wounds with topical beta adrenergic antagonists (Timoptic®).

Description

The purpose of this study is to learn more about how to heal venous leg ulcers faster and to test the safety of a drug and see what effects it has on a venous leg ulcer.

You will:

- be interviewed and examined

- have a physical exam

- have blood and urine tested

- have photographs taken of the wound

- apply medication to the leg ulcer as directed

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Ulcer

Intervention

Timoptic

Location

VA Medical Center
Mather
California
United States
95655

Status

Recruiting

Source

University of California, Davis

Results (where available)

View Results

Links

Clinical Trials [117 Associated Clinical Trials listed on BioPortfolio]

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Surveillance of Bleeding Peptic Ulcer Using Wireless Capsule Endoscopy

To investigate the adjunctive role of “Capsule Endoscope” in continuous endoscopic monitoring and early detection of recurrent ulcer bleeding after endoscopic therapy in patients prese...

Study of Individualized Wound Prevention Instruction to Prevent Venous Ulcer Development

The purpose of this study is to determine whether individualized wound prevention instructions will lengthen the ulcer-free period in veterans with recently healed venous ulcers.

PubMed Articles [298 Associated PubMed Articles listed on BioPortfolio]

Single nucleotide polymorphism markers for low-dose aspirin-associated peptic ulcer and ulcer bleeding.

In our previous study, the SLCO1B1 521TT genotype and the SLCO1B1*1b haplotype were significantly associated with the risk of peptic ulcer in patients taking low-dose aspirin (LDA). The aim of the pre...

Endoscopic management of peptic ulcer bleeding.

Acute upper gastrointestinal bleeding is a common medical emergency around the world and the major cause is peptic ulcer bleeding. Endoscopic treatment is fundamental for the management of peptic ulce...

The Role of Nutrition for Pressure Ulcer Management: National Pressure Ulcer Advisory Panel, European Pressure Ulcer Advisory Panel, and Pan Pacific Pressure Injury Alliance White Paper.

To review the 2014 Pressure Ulcer Prevention and Treatment Clinical Practice Guideline nutrition strategies.

The Role of Nutrition for Pressure Ulcer Management: National Pressure Ulcer Advisory Panel, European Pressure Ulcer Advisory Panel, and Pan Pacific Pressure Injury Alliance White Paper.

Is History of Ulcer an Adverse Factor for Laparoscopic Repair of Peptic Ulcer Perforation?

Medical and Biotech [MESH] Definitions

A PEPTIC ULCER located in the DUODENUM.

Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Bleeding from a PEPTIC ULCER that can be located in any segment of the GASTROINTESTINAL TRACT.

Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY.

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.

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