Beta Blocker for Chronic Wound Healing

04:19 EDT 1st November 2014 | BioPortfolio

Summary

The purpose of this study is to evaluate the efficacy and safety of treatment of chronic cutaneous ulcers and burn wounds with topical beta adrenergic antagonists (Timoptic®).

Description

The purpose of this study is to learn more about how to heal venous leg ulcers faster and to test the safety of a drug and see what effects it has on a venous leg ulcer.

You will:

- be interviewed and examined

- have a physical exam

- have blood and urine tested

- have photographs taken of the wound

- apply medication to the leg ulcer as directed

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Ulcer

Intervention

Timoptic

Location

VA Medical Center
Mather
California
United States
95655

Status

Recruiting

Source

University of California, Davis

Results (where available)

View Results

Links

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Study of Individualized Wound Prevention Instruction to Prevent Venous Ulcer Development

The purpose of this study is to determine whether individualized wound prevention instructions will lengthen the ulcer-free period in veterans with recently healed venous ulcers.

PubMed Articles [317 Associated PubMed Articles listed on BioPortfolio]

Idiopathic cecal ulcer: report of a case.

The idiopathic cecal ulcer is rare in frequency, there are case reports and small series in the literature but in Peru have not been described yet. They are of unknown etiology and wide differential d...

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Marjolin's ulcer in scarred tissue and non-healing ulcers.

The term "Marjolin's ulcer" describes the formation of a malignant tumour in chronically inflamed skin such as non-healing ulcers or previously traumatized, burned or scarred tissue. Usually the patie...

Ulcer pain in patients with venous leg ulcers related to antibiotic treatment and compression therapy.

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Value of the calcium-regulating system in the development of microcirculatory and hemostatic disorders in recurrent peptic ulcer disease.

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Medical and Biotech [MESH] Definitions

A PEPTIC ULCER located in the DUODENUM.

Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Bleeding from a PEPTIC ULCER that can be located in any segment of the GASTROINTESTINAL TRACT.

Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY.

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.

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