Comparison Study of Operation and PEIT for Small, Solitary Hepatocellular Carcinoma (HCC)

20:09 EST 20th December 2014 | BioPortfolio

Summary

The purpose of this study is to choose the preferred treatment modality for solitary, small hepatocellular carcinoma.

Description

To compare the below things between operation group and percutaneous ethanol injection therapy (PEIT) group:

1. Survival

- 5 year overall survival rate

- Disease free survival rate

2. Recurrence

- Cumulative recurrence rate

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Hepatocellular Carcinoma

Intervention

Operation, Percutaneous ethanol injection therapy

Location

Seoul NUH
Seoul
Chongno-gu
Korea, Republic of
110-744

Status

Recruiting

Source

Seoul National University Hospital

Results (where available)

View Results

Links

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PubMed Articles [17486 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

Percutaneous excision of a herniated or displaced intervertebral disk by posterolateral approach, always remaining outside the spinal canal. Percutaneous nucleotomy was first described by Hijikata in Japan in 1975. In 1985 Onik introduced automated percutaneous nucleotomy which consists in percutaneous aspiration of the nucleus pulposus. It is carried out under local anesthesia, thus reducing the surgical insult and requiring brief hospitalization, often performed on an outpatient basis. It appears to be a well-tolerated alternative to surgical diskectomy and chymopapain nucleolysis.

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An ORTHOHEPADNAVIRUS causing chronic liver disease and hepatocellular carcinoma in woodchucks. It closely resembles the human hepatitis B virus.

The type species of the genus ORTHOHEPADNAVIRUS which causes human HEPATITIS B and is also apparently a causal agent in human HEPATOCELLULAR CARCINOMA. The Dane particle is an intact hepatitis virion, named after its discoverer. Non-infectious spherical and tubular particles are also seen in the serum.

The first alpha-globulins to appear in mammalian sera during development of the embryo and the dominant serum proteins in early embryonic life. They reappear in the adult serum during certain pathologic states, primarily hepatocellular carcinoma. They may also be elevated in the amniotic fluid and maternal serum during pregnancy in ANENCEPHALY.

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