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Abilify as an Adjunctive Treatment for Refractory Depression.

2014-07-23 21:47:48 | BioPortfolio

Summary

This is a study of the effectiveness of adding Abilify (aripiprazole), an atypical antipsychotic medication, to ongoing SSRI antidepressant treatment for depressed outpatients who are not responding fully to SSRI treatment alone. It is hypothesized that patients’ functioning will improve after 12 weeks of treatment with Aripiprazole and SSRI medication.

Description

This is a pilot study of the effectiveness of adding Abilify (aripiprazole), an atypical antipsychotic medication, to ongoing SSRI antidepressant treatment for depressed outpatients who are not responding fully to SSRI treatment alone. Fifteen subjects will be given aripiprazole in a flexible dosing schedule and followed for 12 weeks, while continuing their ongoing SSRI medication. Assessments of depressive symptoms, overall functioning, social functioning, and side effects will be completed. It is hypothesized that patients’ functioning will improve after 12 weeks of treatment with Aripiprazole and SSRI medication.

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Depressive Disorder, Major

Intervention

Abilify (aripiprazole)

Location

Mood Disorders Research Program, St. Luke's Roosevelt Hospital
New York
New York
United States
10019

Status

Completed

Source

St. Luke's-Roosevelt Hospital Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:47:48-0400

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Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.

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