Shorter Radiation Schedule for the Treatment of Prostate Cancer
To improve the management of patients with early stage prostate cancer.
To compare the efficacy of a shorter radiation fractionation schedule to the prostate (5250 cGy/20 fractions over 28 days) with a conventional schedule (6600 cGy/33 fractions over 45 days) in men receiving radiotherapy for Stage T1a moderately or poorly differentiated, or T1b, T1c, or T2 prostate cancer. The primary outcome is local control in the prostate and secondary outcomes include toxicity, disease free survival, survival, quality of life and economics.
Allocation: Randomized, Control: Dose Comparison, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
5250 cGy/20 fractions over 28 days, 6600 cGy/33 fractions over 45 days
B.C. Cancer Agency - Fraser Valley Cancer Centre
Active, not recruiting
Ontario Clinical Oncology Group (OCOG)
Results (where available)
- Source: http://clinicaltrials.gov/show/NCT00201916
- Information obtained from ClinicalTrials.gov on July 15, 2010
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Medical and Biotech [MESH] Definitions
Postnatal deaths from BIRTH to 365 days after birth in a given population. Postneonatal mortality represents deaths between 28 days and 365 days after birth (as defined by National Center for Health Statistics). Neonatal mortality represents deaths from birth to 27 days after birth.
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CHILDBIRTH before 37 weeks of PREGNANCY (259 days from the first day of the mother's last menstrual period, or 245 days after FERTILIZATION).
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Techniques to partition various components of the cell into SUBCELLULAR FRACTIONS.