Advertisement

Topics

Diagnostics and Therapy of Disease-Related Quality of Life of Patients With Breast Cancer

2014-08-27 03:51:54 | BioPortfolio

Summary

Quality of Life-Diagnostics and -Therapy in Individual Patients with Breast Cancer.

A randomized study including 200 patients, 5 clinics and 43 general practitioners as coordinating doctors for quality of life therapies.

Description

Quality of life (QL) is increasingly being accepted as an important endpoint in clinical studies, however little is known about its diagnostic value in order to optimize the therapy of cancer patients. This project at the Tumorcentre Regensburg aims to integrate QL-diagnostics into the therapy of patients with breast cancer and to evaluate the efficacy of QL-diagnostics in the context of a randomized clinical trial.

The Tumorcentre Regensburg provides the infrastructure of the present project (telemedicine, project groups, quality circle). Breast cancer patients' therapy is based on the recent national breast cancer therapy guideline, including assorted QL-enhancing therapy options, such as pain therapy, physiotherapy and lymphatic drainage, psychotherapy, social counseling and rehabilitation, nutrition and sports.

In the course of an implementation phase, a new method of QL diagnostics has been developed. Five experts with varying professional background use the individual patient's QL profile and clinical and sociodemographic information in order to generate a QL-report including a therapy recommendation.

This is a two-arm randomized clinical trial with one test group (communication of the QL-finding to the coordinating physician) and a control group (no communication). Patients with newly diagnosed breast cancer who are treated in the study region by one of the coordinating doctors will be included in this randomized study. QL-assessments (EORTC QLQ-C30 plus BR23) will be taken at designated points in time over a 12 months time course. Finally, patients will provide an overall evaluation of the course and the effects of the therapy using an open-ended questionnaire.

We expect that patients in the test group will experience a lower number of QL-deficits at the end of the study period (Median 1 +/- 2) than patients of the control group (Median 2 +/- 2). The statistical confirmation of this expected effect requires a total sample size of N = 200 (n=100 vs. n=100, alpha = 5% [two-tailed], beta = 10%).

This is the first study to evaluate a new form of QL-diagnostics in the complexity of a real patient care environment. This study promises to reveal important new insights into advanced patient care and will make the inclusion of the quality of life concept in the current breast cancer treatment guideline more concrete.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Conditions

Breast Neoplasms

Intervention

physio,pain,psychotherapy;social,nutrit.counselling&sports

Location

Tumorzentrum Regensburg
Regensburg
Bavaria
Germany
93053

Status

Completed

Source

Tumorzentrum Regensburg e.V.

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:51:54-0400

Clinical Trials [2990 Associated Clinical Trials listed on BioPortfolio]

Implementation of Quality of Life Diagnostics and Therapy

Implementation and Evaluation of Implementation of Quality of Life Diagnostics and Therapy in Individual Patients with Breast Cancer. A prospective study including 170 patients, 5 clinics ...

Effectiveness of Physiotherapy for Chronic Shoulder Pain

The purpose of this study is to investigate whether a physiotherapy program reduces pain and improves disability and quality-of-life in people with chronic shoulder pain. The main study h...

Psychomotor Therapy as Complimentary Treatment to Patients With Shoulder Pain.

Some patients with shoulder pain have decreased body awareness (BA). To some degree, pain among these patients can be increased due to their lack in BA. Psychomotor therapy is thought to i...

Integrative Ayurveda Healing Relieves Minor Sports Injury Pain

Sports-related soft tissue injuries, such as sprains, strains, and contusions, are a common painful condition. Current treatment includes oral nonsteroidal anti-inflammatory drugs (NSAIDs)...

Physiotherapy for Sciatica; Is Earlier Better?

This study aims to evaluate the whether receiving physiotherapy early after onset of the problem is better than waiting a few weeks to see if it gets better before starting physiotherapy. ...

PubMed Articles [13228 Associated PubMed Articles listed on BioPortfolio]

Concerns about Breast Cancer, Pain, and Fatigue in Non-Metastatic Breast Cancer Patients Undergoing Primary Treatment.

Women diagnosed with breast cancer often endorse psychosocial concerns prior to treatment, which may influence symptom experiences. Among these, low perceived social support relates to elevated fatigu...

To be spurned no more: The affective and behavioral consequences of social and nonsocial rejection.

Social pain is often associated with social rejection and shares neural correlates with the bothersome aspect of physical pain, which may also indicate an overlap in function. Pain has been described ...

Contemporary social media engagement by breast surgeons.

There continues to be a steady rise in the use of social media among healthcare professionals. We present an overview of social media use among breast surgeons within the United Kingdom including demo...

Persistent Breast Pain Among Women With Histories of Breast-conserving Surgery for Breast Cancer Compared With Women Without Histories of Breast Surgery or Cancer.

This study compared persistent breast pain among women who received breast-conserving surgery for breast cancer and women without a history of breast cancer.

Prevalence of Back Pain in Sports: A Systematic Review of the Literature.

Back pain is a frequent health problem in the general population. The epidemiology of back pain in the general population is well researched, but detailed data on the prevalence and risk factors of ba...

Medical and Biotech [MESH] Definitions

Unilateral or bilateral pain of the shoulder. It is often caused by physical activities such as work or sports participation, but may also be pathologic in origin.

A fluid-filled closed cavity or sac that is lined by an EPITHELIUM and found in the BREAST. It may appear as a single large cyst in one breast, multifocal, or bilateral in FIBROCYSTIC BREAST DISEASE.

Illegitimate use of drugs for a desired effect in competitive sports; includes humans and animals.

The use of more than one therapist at one time in individual or group psychotherapy.

Any form of psychotherapy designed to produce therapeutic change within a minimal amount of time, generally not more than 20 sessions.

More From BioPortfolio on "Diagnostics and Therapy of Disease-Related Quality of Life of Patients With Breast Cancer"

Quick Search
Advertisement
 

Relevant Topics

Breast Cancer
Track and monitor developments in breast cancer research and commercial development.  Follow the tabs above to read the latest global news, research, clinical trials on breast cancer and follow companies active in the development of breast cancer tr...

Cancer
  Bladder Cancer Brain Cancer Breast Cancer Cancer Cervical Cancer Colorectal Head & Neck Cancers Hodgkin Lymphoma Leukemia Lung Cancer Melanoma Myeloma Ovarian Cancer Pancreatic Cancer ...


Searches Linking to this Trial