IV Cocaine Abuse: A Laboratory Model - 4
The purpose of this study is to evaluate the effects of pergolide on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving in non-opiate dependent cocaine users.
Primary Purpose: Treatment
National Institute on Drug Abuse (NIDA)
Results (where available)
- Source: http://clinicaltrials.gov/show/NCT00000215
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Disorders related or resulting from use of cocaine.
The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intravenously, and orally ingested. Use of crack results in alterations in function of the cardiovascular system, the autonomic nervous system, the central nervous system, and the gastrointestinal system. The slang term "crack" was derived from the crackling sound made upon igniting of this form of cocaine for smoking.
Disorders related to substance abuse, the side effects of a medication, toxin exposure, and ALCOHOL-RELATED DISORDERS.
Disorders related or resulting from abuse or mis-use of opioids.
Disorders related or resulting from use of amphetamines.
The purpose of this study is to evaluate the safety and efficacy of pergolide for cocaine dependence.
The purpose of this study is to evaluate the efficacy and safety of pergolide for treatment of cocaine dependence.
The purpose of this study is to evaluate the effects of buprenorpine on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving in non-opiate d...
To study of classical conditioning mechanisms associated with arousal, craving and cocaine use.
The purpose of this study is to compare the effects of buprenorphine or methadone maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocain...
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