Ocular Comfort and the "Aging" Lens (ERBIUM)
The purpose of this trial is to evaluate the factors affecting comfortable contact lens wear and how those factors affect contact lens replacement frequency.
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment
Habitual contact lens, Lotrafilcon B contact lens
University of Waterloo
Results (where available)
- Source: http://clinicaltrials.gov/show/NCT01198600
- Information obtained from ClinicalTrials.gov on February 14, 2012
Medical and Biotech [MESH] Definitions
Contact Lens Solutions
Sterile solutions used to clean and disinfect contact lenses.
Lens Implantation, Intraocular
Insertion of an artificial lens to replace the natural CRYSTALLINE LENS after CATARACT EXTRACTION or to supplement the natural lens which is left in place.
The clear, watery fluid which fills the anterior and posterior chambers of the eye. It has a refractive index lower than the crystalline lens, which it surrounds, and is involved in the metabolism of the cornea and the crystalline lens. (Cline et al., Dictionary of Visual Science, 4th ed, p319)
A subclass of crystallins that provides the majority of refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Alpha-crystallins also act as molecular chaperones that bind to denatured proteins, keep them in solution and thereby maintain the translucency of the lens. The proteins exist as large oligomers that are formed from ALPHA-CRYSTALLIN A CHAIN and ALPHA-CRYSTALLIN B CHAIN subunits.
Examination of the angle of the anterior chamber of the eye with a specialized optical instrument (gonioscope) or a contact prism lens.
This study seeks to evaluate the clinical and subjective performance of a new daily disposable soft contact lens.
The primary objective of this trial is to compare the performance of lotrafilcon B to habitual HEMA and SiHy spherical contact lenses in a selected segment of the contact lens wearing popu...
The purpose of this study is to compare visual acuity and redness of eyes between a new contact lens and an already marketed contact lens.
This study seeks to evaluate the clinical performance of a recently released contact lens designed to correct astigmatism to an established contact lens that has historically been used in...
Assess the performance of lotrafilcon A contact lenses that may or may not have been modified by means of design changes (within allowable approvals).
PURPOSE: To examine the relative changes in modulus of nine soft contact lens materials when exposed to three lens care solutions. METHOD: Measurements of elastic modulus were made using an Instron 33...
PURPOSE: To understand various soft contact lens materials' ability to adsorb common tear lipids. METHODS: Ten unworn polymers of 9 types were individually soaked in 1.0 mL of 1.75 microg/mL cholester...
Propylene glycol used as an ophthalmic demulcent in certain contact-lens care systems has been included recently among factors responsible for increasing Acanthamoeba keratitis. In this study, we prov...
Tear proteomic studies revealed distinct similarities between contact lens wearers and dry eye patients. AMO Complete® multipurpose contact lens cleaning solutions containing taurine seem to have a b...