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PRESSUREwire Study

2016-10-18 02:08:21 | BioPortfolio

Summary

The purpose of this study is to understand routine use of FFR and alternate indices in clinical practice. This study will determine the use and clinical outcome of FFR-guided PCI in patients presenting with either stable coronary artery disease, or in patients presenting with Acute Coronary Syndrome (ACS) on culprit and non-culprit lesions as well as during index and secondary procedures.

Description

The purpose of this study is to understand routine use of FFR and alternate indices in clinical practice. This study will determine the use and clinical outcome of FFR-guided PCI in patients presenting with either stable coronary artery disease, or in patients presenting with Acute Coronary Syndrome (ACS) on culprit and non-culprit lesions as well as during index and secondary procedures.

The study will also collect data on the routine use of coronary physiologic measurements such as adenosine-induced hyperemia FFR, FFR by contrast-induced hyperemia,

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Conditions

Coronary Artery Disease

Intervention

Fractional Flow Reserve

Location

Orlando Health
Orlando
Florida
United States
32806

Status

Recruiting

Source

St. Jude Medical

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-10-18T02:08:21-0400

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Regadenoson to Achieve Maximal Hyperemia for Fractional Flow Reserve in the Catheterization Lab

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Validation of Stenosis Assessment by Coronary Artery Computed Tomography Against Invasive Measurements of Fractional Flow Reserve in Patients With Significant Coronary Artery Stenoses

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PubMed Articles [22670 Associated PubMed Articles listed on BioPortfolio]

Fractional flow reserve and pressure-bounded coronary flow reserve to predict outcomes in coronary artery disease.

Fractional flow reserve (FFR) has proven to its prognostic and therapeutic value. However, the additive prognostic value of coronary flow reserve (CFR) remains unclear. This study sought to investigat...

Comparison between fractional flow reserve and visual assessment for moderate coronary artery stenosis.

'Fractional flow reserve (FFR)' is an interventional diagnostic method based on intracoronary pressure measurement used for the assessment of the severity of coronary artery stenoses. Our study aimed ...

TCT-533 Fractional Flow Reserve And Coronary Flow Reserve To Predict Outcomes in Coronary Artery Disease.

Fractional flow reserve: a clinical perspective.

Fractional flow reserve (FFR) is a reference invasive diagnostic test to assess the physiological significance of an epicardial coronary artery stenosis. FFR-guided percutaneous coronary intervention ...

Quantitative myocardial blush grade reserve during pharmacologic hyperaemia: a way to perform a real wireless fractional flow reserve measurement in patients with coronary artery disease and intermediate coronary lesions.

We investigated the relation between myocardial blush grade reserve (MBGreserve) and fractional flow reserve (FFR) measures. FFR is a marker of inducible myocardial ischaemia, which could guide percut...

Medical and Biotech [MESH] Definitions

The ratio of maximum blood flow to the MYOCARDIUM with CORONARY STENOSIS present, to the maximum equivalent blood flow without stenosis. The measurement is commonly used to verify borderline stenosis of CORONARY ARTERIES.

Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.

A complication of INTERNAL MAMMARY-CORONARY ARTERY ANASTOMOSIS whereby an occlusion or stenosis of the proximal SUBCLAVIAN ARTERY causes a reversal of the blood flow away from the CORONARY CIRCULATION, through the grafted INTERNAL MAMMARY ARTERY (internal thoracic artery), and back to the distal subclavian distribution.

Direct myocardial revascularization in which the internal mammary artery is anastomosed to the right coronary artery, circumflex artery, or anterior descending coronary artery. The internal mammary artery is the most frequent choice, especially for a single graft, for coronary artery bypass surgery.

A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

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