Study on the Anti-HPA Antibodies Caused Neonatal Alloimmune Thrombocytopenia in Chinese Pregnant Women

2016-10-18 02:08:21 | BioPortfolio


This clinical study aims to investigate the anti-HPA antibodies caused neonatal alloimmune thrombocytopenia in Chinese pregnant women. The survey and data collect will help form an appropriate clinical screening procedure

Study Design

Observational Model: Cohort, Time Perspective: Prospective


Neonatal Alloimmune Thrombocytopenia


Standard clinical treatment, including intravenous immunoglobulin and/or platelet transfusion


Not yet recruiting


Xinqiao Hospital of Chongqing

Results (where available)

View Results


Published on BioPortfolio: 2016-10-18T02:08:21-0400

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Medical and Biotech [MESH] Definitions

Immunoglobulin preparations used in intravenous infusion, containing primarily IMMUNOGLOBULIN G. They are used to treat a variety of diseases associated with decreased or abnormal immunoglobulin levels including pediatric AIDS; primary HYPERGAMMAGLOBULINEMIA; SCID; CYTOMEGALOVIRUS infections in transplant recipients, LYMPHOCYTIC LEUKEMIA, CHRONIC; Kawasaki syndrome, infection in neonates, and IDIOPATHIC THROMBOCYTOPENIC PURPURA.

Human alloantigens expressed only on platelets, specifically on platelet membrane glycoproteins. These platelet-specific antigens are immunogenic and can result in pathological reactions to transfusion therapy.

Antibodies produced by human or animal cells following clinical or experimental exposure to parasitic HELMINTH ANTIGENS. The IMMUNOGLOBULIN E class of immunoglobulins is usually formed and released, but IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; and IMMUNOGLOBULIN A may also occur.

The transfer of blood platelets from a donor to a recipient or reinfusion to the donor.

In utero transfusion of BLOOD into the FETUS for the treatment of FETAL DISEASES, such as fetal erythroblastosis (ERYTHROBLASTOSIS, FETAL).

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