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Tranexamic Acid for Preventing Postpartum Hemorrhage After Cesarean Section

2016-10-19 02:38:21 | BioPortfolio

Summary

It is a multicenter randomized, double-blind and placebo-controlled trial. Totally 6500 women to delivery by cesarean section will be recruited in this study. In addition to routinely oxytocin, the women in study group will receive TXA 1 g in 2 minutes after they delivered their babies, and those in control group will receive placebo. The incidence of postpartum hemorrhage, the amount of bleeding, as well as the side effects will be observed.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Conditions

Postpartum Hemorrhage, Cesarean Section

Intervention

Tranexamic Acid, Placebo

Status

Not yet recruiting

Source

Shanghai First Maternity and Infant Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-10-19T02:38:21-0400

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Medical and Biotech [MESH] Definitions

Delivery of an infant through the vagina in a female who has had a prior cesarean section.

Extraction of the fetus by abdominal hysterotomy anytime following a previous cesarean.

Antifibrinolytic hemostatic used in severe hemorrhage.

Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).

Extraction of the FETUS by means of abdominal HYSTEROTOMY.

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